TRUBOND

Trubond :
It is a unique combination of prebiotic and Probiotics (Symbiotic), Organic acids, vitamins and minerals in which give a synergistic effect to increase and maintain a healthy bacterial gut flora and foundation of the non-specific immune system against pathogen and controlling of mycotoxins either by bio-agglutination (MOS) or biotransformation (live beneficial bacterial and yeast )
Composition:
1) Prebiotic : Mannane oligoisaccaride (yeast cell wall extract)
2) Probiotic: A unique combination of live bacteria and yeast includes:- Saccharomyces Cerevisiae, Enterococcus faecium, Lactobacillus acidophilus, lactobacillus subtilis, Lacobacillus casei, Lactobacillus plantarrum and Lactobacillus brevis.
3) 3. Cocktail of Organic and Inorganic Acids
4) 4. Vitamins & Minerals


How does Trubond work?
o Role of MOS :
1. Bio- agglutination for toxin particles regardless their polarity: MOS provides large areas of adsorption with different pore sizes, which can adsorb different types of mycotoxins.

2. Act as Dummy Sites for Gram negative Pathogenic Bacteria: The bacteria bind to these MOS particles (with their mannose-specific type-1 fimbriae), and pass through the gut, instead of attaching to the host cells.



3. Enhances Humoral and Cellular Immunity Response
o Role of Probiotics: Direct feed microbial
o Improving intestinal microbial balance “
o Prevents harmful bacteria from growing in the gut by (competitive exclusion method).
o Improves the non-specific immune response.
o Restoring the normal bacterial population that was.
o Increases enzymatic activity & absorption in the intestine
o Lactic acid bacteria produce antimicrobials that inhibit intestinal pathogens


Biotransformation of Toxins (less polar toxins):
It is a change in the nature or iso-transformation of a certain substance (Toxin particle) either changes into a less toxic or nontoxic substance (detoxified). Biotransformation neutralizes the toxic effect of mycotoxins
a) T2 toxins: through reduction of the 12, 13 epoxide group by de-epoxidases enzymes activity to yield a carbon – carbon double bond that lead to less toxic molecule.
b) Zearalenone detoxification :
Transformation of the chemical structure of the toxin molecules by the yeast strains (ester hydrolysis) into a similar molecule but non toxic.















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