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Impact of Deoxynivalenol in the large intestine of pre-pubertal gilts

The Effect of 42-Day Exposure to a Low Deoxynivalenol Dose on the Immunohistochemical Expression of Intestinal ERs and the Activation of CYP1A1 and GSTP1 Genes in the Large Intestine of Pre-pubertal Gilts

Published: March 20, 2024
Summary
INTRODUCTION Mycotoxins are substances that occur naturally in the environment (1, 2). In addition to mycoestrogens such as zearalenone (3, 4), selected trichothecenes, including DON and/or its metabolites (but in vitro), can affect steroidogenesis (2) and changes in gene expression, which suggests that these compounds could disrupt hormonal homeostasis (1). Deoxynivalenol (DON), a polar orga...
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Authors:
Lukasz Zielonka
University of Warmia and Mazury in Olsztyn (UWM)
University of Warmia and Mazury in Olsztyn (UWM)
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Jonathan Tarus
16 de diciembre de 2024
Wonderful job done on this challenge. More should be done on other spp- to make the farm save from this 'silent terrorist'. Bravo.
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