QX infection in adult breeder layer
I would be grateful if somebody tell me if it is possible to vaccinate by 4/91 two weeks after Ma5 to control QX variant in adult breeder .
Using I.B. multi strain vaccine (killed) seem to be a better option.
I.B variants are mutating fast and may be spreading through live vaccines?
Which killed vaccine can be used? Is it tried through a trial?
what is the route of vaccination for ib vaccination in production?
drinking water or spraying?
Respected Sirs
Thank you so much for that valuable comments .Definitely we did as you mentioned during rearing period. In spite of that, QX hit the flock during laying. Is it possible to repeat Ma 5 and 4/91 after two weeks or what to do? That is my inquiry.
Thanks and regards.
Dr. Salah Ali
Beta-Glucan Effects on Vaccine Responses and Innate Immunity in Layers
Salah Mohammed The best protection from IB variant strain is usually a homologous live vaccine. Today, we have the advantage of understanding what variant or variants are circulating on the farm. so if you have QX field strain use the QX vaccine and do it more than once. try to vaccinate with as less IB strains as possible as too many vaccines will interfere with each other. In high challenge area, use live vaccine 2-3 times during the pullets stage and make the last live vaccination before point of lay. wait until AFTER peak and start vaccinating every 6-8 months. Best application- Spray or ED.
Udi Ashash. Yes I totally agree with you, just one comment as the early infection from QX will cause false lay it is very useful to be used at early age. In the middle east area, we are advising to be used at early age Like day one QX, 14 days mass. Strain.
Salah Mohammed,
1-Honestly with QX problem is not how many dose you use more than to use it in right time, which is at early age. For sure it is good if you use other variate strain in your vaccine program.
The most important is to have 2 weeks interval with other rep. vaccines to avoid interference issue, do not mix the vaccines with other vaccines without hard approval that they are working together, same when they are alone. The main problem is when mixing by ourselves the ND, IB and IB variant together (not by producers) in this case definitely we are losing benefits of these vaccines. I know some will say we have used it and everything is ok, what I can say is that is lucky, but as soon there is high challenge you can see the real problem.
2- To get good protection during lay killed vaccine with more IB strains help a lot by increasing the antibodies against, as you know as much we have high antibodies as much you get protraction. We have great experience with IB3+ND+Eds vaccine from Vaxxinova to get high IB titres during production. Also we are advising after peak to use IB+ND live to get good local immunity during production.
LIPTOSA
Hi to all:
To control of QX Bronchitis pathogenesis in breeder to prevent left oviduct cyst, need to note the following factors.
1- Good cleaning and disinfection of poultry house before chick arrival.
2- to buy day old chicks by good maternal immunity against QX strain.
3- Good vaccination program including protectotype strategy.
As all know QX strain pathogenesis occur in first weeks of life (2-3) when the oviduct tissue yet not changes complete from embryonic phase to lifetime .hence when there is a history of disease in before flocks the vaccination program can starts by vaccination against 793B variant (4/91- ibird - IB88) by spry method . followed by Maschu- H120 tow week later.
some expert recommend to use both vaccine(Ma5+4/91) in day old by spry method. It stimulates upper respiratory and systemic immunity.
If before start of production multi strain killed vaccine be used it acts as a booster and better immunity for breeder in lifetime and good maternal immunity for progeny.
Vaccination by any kind of vaccine after about 3 weeks of age has not any protection against QX strain that induces left oviduct cyst but acts to prevent respiratory disease and reducing egg production and egg quality in production period.
Zahed Abbasi,
Extremely correct. First, hygiene, then vaccinations for the protection of health and quality production.
Frankly, Biosecurity and Good SOP in breeder farm (disinfecting, cleaning, day to day monitoring) are the crucial action against IBV field strains, otherwise a punch of vaccine will never confer protection, here we are know needing new strategy to characterize and identify the genotype of field challenge immediately, then use the closet vaccine strain, the advance in metagenomic analysis might be helpful in nearest days, using multiple vaccine strain is the only method followed by technical in the field, whereas using the classical H120 and H48 or even 52 Luhmann might mitigate losses for any field challenge emerged since its the master seed.
I think before giving the IB VAC we should at least study the area disease history: frequent variants will lead to immunocompromised birds. Be careful I think, two variants is more than enough, focusing on SOP of the farm, ventilation system, finally using the mass strain periodically from different companies in layer and breeder.
Hangzhou DE Mark Industrial Co Ltd
