Fowl Cholera in poultry

I am interested to know the vaccination schedule for the control of FC .we are using killed bacterin at age of 12wks followed by boosted after 12 wks. no satisfactory results.

Probiotics are beneficial bacteria or yeast that are healthy to the intestine of the animal
Probiotics mimic gram negative flagellated bacteria such as E Coli pasteurekka and other harmful bacteria by competing to attach to their receptive sites
So when probiotics are fed to monogastrics, for example, they get attached to the lumen epithelium receptive sites, that are attachments sites for gram negative bacteria as mentioned above
When these predilection sites for pathogenic bacteria are occupied by these probiotics, they make these flagellated bacteria unable to get themselves attached to where their sites, where they cause erosion of the intestinal lining leading to hemorrhages
The result if this process is that these pathogenic bacteria are found floating in the gut lumen until they are pushed out with the fasces thus preventing the animal from been susceptible to this infection
From the above mechanism, it is obvious that the use if probiotics will enhance the proliferation of gram positive bacteria that is beneficial to the animal immune system
Since probiotics and neutraceuticals are natural products they act as non-antibiotic growth promoters because they improved the villi morphology and improve gut health and absorption efficiency.

Although farmers are using probiotics both in feed as well in water but results are up to the desirables levels.

Probiotics are beneficial bacteria or yeasts that improve gut health, digestibility and immune system, especially in monogastrics. Probiotics are very competitive to the survival of the gram negative bacteria in the gut ,because they compete with these harmful bacteria receptive sites
You should take note that the pathogenic gram negative bacteria are mostly flagellated like the and they are all harmful to the host
In the pathogenesis of gram negative flagellated bacteria, they start their damage in the lumen of the host gut by getting attached to specific receptive sites on the epithelium of the gut, and proceed in their pathology by eroding the surfaces of the sites, thus causing inflammation and poor digestibility and absorption. When Probiotics are fed to animals, they compete to attach to these sites.

Dr. Charles Ibe, thanks a lot.

How to use probiotics in poultry?

In layers vaccination is important. Use of Acidifiers have better results to control FC.

I rear layer birds and lately I observed my bird will go to the corner of the pen and fold up, wisin for breath and few hours after they will die. There is no sign of mucus on their nostril and they can hardly walk, please help what to used to help my birds
. E.Wills

Despite all positive control mechanisms, ceftriaxone is the most crucial drug to control heavy mortality within a short period. I have been using it since 2017 in Bangladesh.

Aoa everyone Has someone knowledge of Insect farming for poultry feed protein requirements and its brooding rearing and harvesting. How can we produce this cheaper source of protein for poultry feed?

Folarin Fale
Hello and thank you for your question. These two diseases, Fowl Cholera and Fowl Typhoid, are very different and are caused by Pasteurella multocida or Salmonella Gallinarum, respectively.
For antibiotic treatment you should always try to, first, isolate the bacteria and ask for your lab to perform antibiotic sensitivity tests before applying any treatment.
Results may change in different countries / regions, and are highly influenced by the antibiotics that were used before and due to great differences between bacteria.
This was you can use the right antibiotic and as well, reduce the chance to create a multi resistant bacteria.

Good discussion but FC also mutated at different farms, culture required most of drugs like chlorom cause hepatomegaly and most of the country are banned so we needs to culture will give us good response and economic loss as well.

multi strain killed vaccines is the answer for prevention. We have coryza+ F.C, which is protecting well. The spread is slow in cages with nipple drinkers compared to water channels and open drinkers on deep litter.
For treatment, injection of long acting tetracycline followed by ulphamethoxol+trimethoprim for week gave me good results.
The article is total information on the disease. The posting is appreciated.

Dr.Talapaneni.Kotaiah thank you for your comments. These two diseases are commonly associated, and a good bacterin, preferably with local strains, will work well.