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Antimicrobials in poultry

Antimicrobial agents are essential tools for treating and controlling bacterial infections in poultry production. Veterinarians have a huge responsibility when using antimicrobials in poultry producing meat and eggs for human consumption. The term ‘judicious use’ of antimicrobials implies the optimal selection of drug, dose and duration of antimicrobial treatment, along with a reduction in inappropriate and excessive use as a means of slowing the emergence of antimicrobial resistance. The proper use of antimicrobials depends on the knowledge of interrelationships between bacteria, antimicrobial, host and consumer. The antimicrobial groups most commonly used in poultry are the betalactams, polypeptides, aminoglycosides and aminocyclitols, macrolides and lincosamides, florfenicol, tetracyclines, sulphonamides, quinolones and fluoroquinolones and ionophores.
Hyun Lillehoj
Hyun Lillehoj and 2 more
USDA - United States Department of Agriculture
USDA - United States Department of Agriculture
INTRODUCTION The intestinal microbiome shapes the gut immune system. In rodents, for example, intestinal colonization by Bifidobacterium infantis or Faecalibacterium prausnitzii stimulates the development of Foxp3 + T regulatory cells (Tregs) and interleukin-10 (IL-10) production, while segmented filamentous bacteria induce proinflammatory T helper 17 (Th17) cell development (Lee and Mazmanian, 2010). In chickens, Yin et al. (2010) reported that an evolving gut...
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Dianna Bourassa
Auburn University
Auburn University
Dianna Bourassa (Auburn University) explained the results obtained in this research using three different levels of peroxyacetic acid to minimize carcass contamination, during IPPE 2019 in Atlanta, USA....
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Dr. Sara J. Steinlage (Elanco) discussed the impact of these measures on poultry health and welfare, during the 2018 NIAA Antibiotic Symposium....
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David Wicker Ph. D.
Fieldale Farms
Fieldale Farms
David Wicker (Fieldale Farms) discussed vaccination, selected breeder flocks, nutrition, supervision and other aspects of antibiotic-free production, during the Multi-State Poultry Feeding and Nutrition Conference in Indianapolis, USA....
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Danny Hooge
Danny Hooge and 4 more
Abstract An experimental direct-fed microbial (DFM) was evaluated in a dose- response trial to determine broiler live performance to 42 d with Coccivac® B at placement (d 0), used litter on d 4, and toxin-producing Clostridium perfringens (Cp) challenges on d 17-18 (by oral gavage and via water trough daily). There were 8 dietary treatment groups with 10 replicate pens of 30 chicks each per treatment (2,400 Cobb 500 straight- run chicks total)....
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Glenn Zhang
Oklahoma State University
Oklahoma State University
1. Introduction In-feed supplementation of antibiotics was firstly reported to promote growth in chickens (Moore et al., 1946) and subsequently in pigs (Jukes et al., 1950; Luecke et al., 1950). Since then, antibiotics have been routinely used in livestock production at subtherapeutic levels for disease prevention and growth promotion and are more commonly known as antibiotic growth promoters (Dibner and Richards, 2005). Unfortunately, continuous long-term exposure of gut...
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Kristina Feye
University of Arkansas (USA)
University of Arkansas (USA)
Kristina Feye (University of Arkansas) discussed the variety of options available to producers to control pathogens, during IPPE 2019 in Atlanta, USA....
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Introduction During broiler carcass processing, evisceration, carcass wash, prechilling and cooling steps can favor the dissemination of microorganisms and carcass contamination (USDA, 2002). One infected broiler arriving at the processing plant may be the source of contamination of many other carcasses (Lillard, 1989; Rasschaert et al., 2008). Some microorganisms present in the broiler intestine, such as Salmonella spp., Campylobacter spp., and thermotolerant coliforms,...
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Leandro Redondo
INTA Argentina
INTA Argentina
INTRODUCTION Antimicrobial agents have been used extensively for prevention and treatment of infectious diseases in food animals (Dibner and Richards, 2005; Niewold, 2007). The concomitant risk of spreading antibiotic resistance to human population through the food supply chain and the environment is important since many classes of these antimicrobial agents are also used in human medicine. Therefore, increased global concern regarding development of antimicrobial...
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Dr. Guillermo Tellez-Isaias
University of Arkansas (USA)
University of Arkansas (USA)
Introduction A common human propensity is to regard all microorganisms as “harmful”, in particular, equating bacteria to pathogenic germs. Nothing could be further from the truth. The number of beneficial bacterial species far exceeds the number of pathogenic species and many of the known bacteria are in fact useful or even indispensable for the continued existence of life on Earth. Prokaryotic microorganisms are...
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Dr. Guillermo Tellez-Isaias
University of Arkansas (USA)
University of Arkansas (USA)
1. Introducción Chitin (C8H13O5N)n) is a long-chain polymer of a N-acetylglucosamine ( Figure 1(a) ), a derivative of glucose, and is found in many places globally. It is the main component of the cell walls of fungi, the exoskeletons of arthropods such as crustaceans (e.g., crabs, lobsters and shrimps) and insects, the radula of mollusks, and the beaks of cephalopods, including squid and octopi [1]. In terms of structure, chitin may be compared to the...
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During the past 50 years, the livestock and poultry industries have developed in several areas including nutrition, genetics, engineering, management, and communications to maximizing the efficiency of growth performance and meat yield. Now these industries must focus more attention on how animal agriculture affects the environment and food safety. As in many other industries, the global paradigm is shifting from an emphasis on productive efficiency to one of public security. Nothing...
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Glenn Zhang
Glenn Zhang and 1 more
Oklahoma State University
Oklahoma State University
Introduction Widespread use of antibiotics as growth promoters in animal feed is suspected to be a major driving force for the development of antibiotic-resistant pathogens, which have become a critical public health concern worldwide. Enhancing host immunity and disease resistance by specifically boosting the synthesis of endogenous host defense peptides (HDPs) may represent a promising antibiotic alternativ-strategy. HDPs have been found in nearly all forms of life and play an...
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Hyun Lillehoj
Hyun Lillehoj and 4 more
USDA - United States Department of Agriculture
USDA - United States Department of Agriculture
Introduction Host defense peptides (HDPs), also known as antimicrobial peptides, are present in virtually all species of life and constitute a critical component of the innate immunity [1,2,3,4,5]. Defensins and cathelicidins represent two major families of HDPs in vertebrates [6,7,8,9,10,11]. While defensins are categorized by the presence of six conserved cysteine residues in the C-terminal mature sequence [6,7,8,11], all cathelicidins consist of a conserved cathelin domain in...
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Nadeem Rashid
Nadeem Rashid and 1 more
INTRODUCTION Feed additives are substances that have the potential to enhance production performance without significantly altering the composition of feed. Broiler chicken requires high dietary energy and protein with balanced amino acid profile in the compound feed (Boling and Firman, 1998). Feed costs approximately about 70% of total production expenditure and nutrient lost in the feces either undigested or unabsorbed due to intestinal microbial population by parasitic action...
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Margie Lee
Margie Lee and 2 more
Virginia Tech
Virginia Tech
Introduction Salmonella remains the leading cause of outbreak-associated gastroenteritis in the United States, and consumption of poultry products has been implicated in several of these outbreaks (1, 2). Since implementation of the HACCP program, improvement has been made in the level of Salmonella contamination of processed chicken carcasses (3). However, a survey of retail meat from the Washington, DC, USA area revealed a surprising level of contamination of beef, pork, and...
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Dr. Badrul Hassan, DVM and PhD student at Uppsala University, Sweden, presents his poster about antibiotic resistance in avian pathogenic Escherichia coli from large and small scale poultry farms in Bangadlesh, at the XVII WVPA Congress in Cancún, Mexico. ...
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Introduction Despite impressive advances in the control of infectious diseases, some bacterial pathogens have acquired antibiotic resistance and are emerging in human populations. Many of these infections are zoonotic and are transmitted from healthy carrier animals to humans through contaminated food (Wegener et al., 2003). For example, Salmonella bacteria, especially the serovars Typhimurium and Enteritidis, are common contaminants of poultry and eggs, causing food-borne...
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