This member will give a presentation on December 16, 2019
At the following event:
3rd International Symposium on Alternatives to Antibiotics
Article published the September 18, 2019
INTRODUCTION Avian coccidiosis is major parasitic disease of high economic concern in the poultry industry worldwide and is caused by at least seven distinct species of Eimeria apicomplexan protozoa that infect the various areas of intestinal mucosa. The economic loss for avian coccidiosis is estimated to be more than $3 billion worldwide (Williams, 1999) and this cost includes in-feed medication ...
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Article published the September 3, 2019
INTRODUCTION Coccidiosis is a ubiquitous intestinal protozoan infection of poultry seriously impairing the growth and feed utilization of infected animals (Lillehoj et al., 2007; Lillehoj and Lillehoj, 2000). Conventional disease control strategies relied heavily on chemoprophylaxis costing the industry tremendously. Existing vaccines comprise live virulent or attenuated Eimeria strains with limi ...
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Article published the August 26, 2019
INTRODUCTION The intestinal microbiome shapes the gut immune system. In rodents, for example, intestinal colonization by Bifidobacterium infantis or Faecalibacterium prausnitzii stimulates the development of Foxp3+ T regulatory cells (Tregs) and interleukin-10 (IL-10) production, while segmented filamentous bacteria induce proinflammatory T helper 17 (Th17) cell development (Lee and Mazmanian, 20 ...
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Article published the August 5, 2019
Background The apicomplexan E.acervulina specifically infects the duodenum resulting in diarrhea, poor feed conversion, and reduced body weight gain, thereby incurring large economic losses to the poultry industry [1]. Traditional disease control methods have relied on chemoprophylaxis with anti-coccidia drugs or immunization with live/attenuated parasite vaccines [2]. However, novel strategies a ...
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Article published the July 26, 2019
INTRODUCTION In the modern intensive production environment, multiple broiler flocks are commonly raised on a single batch of litter where day-old chickens are placed directly on used litter (Volkova et al., 2009). Litter is mainly composed of the bedding materials, feather, manure, the spilled feed and microbiota. Bolan et al. (2010) stated that microbial populations in poultry litter can exceed ...
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Article published the July 22, 2019
Coccidiosis of chickens, one of the most costly diseases affecting the poultry industry worldwide, is caused by infection with one or more of 7 species of the intracellular protozoan parasite Eimeria [1,2]. Eimeria infections occur when susceptible chickens ingest viable sporulated oocysts from contaminated litter. The ingested oocysts invade the intestinal epithelium in a region-specific manner, ...
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Participation in Forum on June 25, 2019
I believe that not all strains of Bacillus will dampen heightened host immune response so we need to screen different Bacillus isolates using in vitro assays and follow with in vivo chicken trials to measure local cytokine gene expression in the gut using PCR or antigen-capture assay.
Participation in Forum on June 25, 2019
There will be an International Symposium on Antibiotic Alternatives in Bangkok in December 16-18, 2019 and many different antibiotic alternatives including Bacillus DFM will be discussed. Check
Participation in Forum on June 25, 2019
I think DFM can play an important role as dietary alternatives to antibiotics and our work also supports this finding that certain strains of bacillus modulate host inflammatory responses and intestinal barrier gene expression of commercial broilers subjected to LPS challenge. Intestinal transcriptomic analysis indicated that B. subtilis-based probiotics differentially regulate intestinal immune a ...
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Location:Beltsville, Maryland, United States
Profile: Professional
Professional Title: Biologist
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