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Afla-V ONE is the world's FIRST lateral flow strip test capable of measuring total aflatoxins in mixed feeds and pet foods using a universal, barcode based calibration. Once calibrated, the Vertu TOUCH reader stores calibration details for future sample analysis, eliminating common bottlenecks such as excessive pipetting, rinsing and waiting!...
I. INTRODUCTION Mycotoxin-contaminated feeds are frequently reported to be more toxic for animals than their purified forms, indicating possible interactions with each other or with the micro-organisms in the animal’s gastrointestinal tract (JECFA, 2002) as bacteria (Galarza-Seeber et al, 2016). The gastrointestinal tract is the largest immune organ, where several immuno-regulatory mechanisms simultaneously defend the body (Belkaid & Hand, 2014). Yet, it is also home...
INTRODUCTION Coffee is one of the most appreciated and consumed beverages in the world (1); however, in its various states, it is susceptible to present a risk of contamination by mycotoxins (2). Mycotoxins are secondary metabolites produced by filamentous fungi that are present in agricultural products due to inadequate food handling and poor storage methods (3,4). Several toxigenic fungi such as Fusarium spp., Aspergillus spp., and Ochratoxigenic species have been found in...
1. Introduction Aflatoxin M1 (AFM1), it is one of five principal metabolites results from the hydroxylation process of Aflatoxin B1 (AFB1). Reaction of enzyme oxidase is associated to cytochrome P 450 of the microsomes within the hepatocytes [1–6]. During this oxidative process, AFB1 is successively transformed into two intermediates, Aflatoxicol (AFL) and Aflatoxicol M1, before turning into AFM1, and in this form it is excreted through milk or eggs [3]. Some...
1. Introduction Aflatoxin M1 (AFM1) is the main metabolite of Aflatoxin B1 (AFB1), which is one of the four most common variants of Aflatoxins (AFs) [1–6]. There is sufficient evidence for the carcinogenicity of AFM1 alone or mixed with AFB1 and Aflatoxin G1 (AFG1) [7], although of lower potency than AFB1 [8,9]. When cattle ingest food or feed contaminated by AFs, it is estimated that up to 6.2 % of the content of AFB1 is transformed into AFM1 and excreted in milk...
INTRODUCTION Impact of the presence of toxigenic fungi in the embryonic egg In practice, 100 % yield can seldom be achieved in egg incubation for “broiler” chicken production (Manders et al., 2021). There are many factors that affect the incubation process and it is essential to know how to do a good analysis of all the available data to know what the problem is and to propose “organic” alternatives that do not modify the percentage yield of...
Johannes Kauffold (University of Leipzig) explained the impact of Zearalenone and DON, during IPVS2022 in Rio de Janeiro, Brazil....
VICAM's Afla-V ONE introduces a NEW approach to aflatoxin detection and management for animal feed and pet food producers worldwide. Obtain fast, actionable results in just minutes, while improving safety and sustainability in the testing and manufacturing environment. Explore the future of aflatoxin detection, today.
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Afla-V ONE is the world's first single-calibration lateral flow strip test method able to detect total aflatoxins in just minutes for complete feeds and pet foods. Designed for use with the Vertu TOUCH lateral flow strip test reader, Afla-V ONE answers a growing need for aflatoxin monitoring in complete feeds, offering on-time data for real-world preventive management. No special training or expertise is required, and Afla-V ONE may be used virtually anywhere....
1 Introduction Fungi have the ability to transform organic materials into a rich and diverse set of useful products and provide distinct opportunities for tackling the urgent challenges before all humans. Fungal biotechnology can advance the transition from our petroleum-based economy into a bio-based circular economy and has the ability to sustainably produce resilient sources of food, feed, chemicals, fuels, textiles, and materials for construction, automotive and...
Introduction Weaning events such as changes in diets, facilities, and littermates are among the factors that cause weaning stress. The weaning stress can lead to inflammatory activation in the intestine and damage of enterocytes [1, 2], reducing the digestibility of nutrients in feeds and nutrient absorption. It has long been demonstrated that pigs weaned at older ages are less susceptible to weaning stress and, thus, have improved feed intake and body weight gain [3–5]....
Introduction Fungal contamination in grains is a serious issue for modern animal production. Mold growth is associated with decreased nutrient content in animal feedstuff (Vieira, 2003). Furthermore, the development of fungi under specific conditions may lead to another major threat: mycotoxin production. In past decades, over one quarter of the world’s food crop production was estimated to be contaminated with mycotoxins (CAST, 2003). Mycotoxins are secondary fungal...
Siska Croubels (Ghent University) speaks on the negative impact of mycotoxins and the different and complementary solutions that are needed to fight it, during IPVS2022 in Rio de Janeiro, Brazil....
Siska Croubels (Ghent University) comments on the main mycotoxins, particularly fumonisins and DON, during IPVS2022 in Rio de Janeiro, Brazil....
Dan Columbus (Prairie Swine Centre and University of Saskatchewan) talked about the effect of mycotoxins, particularly Deoxynivalenol, on short and long term feed intake, during this Swine It interview with host Laura Greiner....
Deoxynivalenol (DON; vomitoxin) is a trichothecene mycotoxin that is produced by Fusarium graminearum (F. graminearum) and is prevalently found in grains such as wheat, corn, barley and their by-products. Food and feed contaminated with DON cause a variety of adverse health effects in humans and farm animals. Poultry are also adversely affected by DON but less susceptible due to differences in DON metabolism. Because of the differences in breeds, types of diet and strains of poultry,...
INTRODUCTION Mycotoxins are secondary metabolic products of fungi with toxigenic effects in other living species. Worldwide, about 88% of animal feed and feedstuffs are contaminated with at least one mycotoxin [1]. Fusarium toxins are the most prevalent, where deoxynivalenol ranks at first with 64% of occurrence, followed by fumonisins and zearalenone [1]. In pigs chronically fed deoxynivalenol contaminated diets, it is observed increased expression of interleukin 8 and...
1. Introduction Aspergillus fumigatus is a saprophytic fungus that can colonize diverse ecological niches facilitated by its great plasticity to adapt to different environments and the wide dispersal of its small, airborne spores called conidia [1,2]. The conidia allow A. fumigatus to reach all chambers of the human respiratory tract, where the fungus is able to cause a wide range of infections depending on the immune status of the patient [3–6]. The biological...
1. Introduction Aspergillus fumigatus is a saprophytic fungus implicated in nitrogen and carbon recycling. Typically of soil decomposers, it is capable of surviving in a wide range of conditions [1]. It has evolved to be a great competitor against other environmental microorganisms because it possesses a controlled nutritional flexibility to scavenge nutrients from the environment efficiently [2]. In addition to these characteristics, its abundant sporulation has gained it a...