Field Efficacy of an Attenuated Infectious Bronchitis Variant 2 Virus Vaccine in Commercial Broiler Chickens
Published:July 2, 2020
Summary
1. Introduction Infectious bronchitis virus (IBV) is a single-stranded enveloped RNA virus that belongs to the genus Gammacoronavirus , family Coronaviridae [1]. The virus causes a clinical disease characterized by coughing, sneezing, tracheal rales, and watery eyes. In layer and breeder chickens, the disease is associated with both quantity and quality deterioration of egg production. Lesion...
A very sensitive and makes a diferent about how we should get our vaccines and tge tyoe according to climate and conditions over this ..plus had seen the boosting of tge vaccines but there are also some areas that drs are not taking on a conscience on this by doing as mentioned and have a detemined vaccines for the area.
Challenge are being seen and heads on to attain the resolution by taking time and make sure they come up with the correct vaccine. Thank so much had learnt and i suggest if all dr under vets should address this each and every region so that the selking of and ibv ot hypravia clone or NCD vaccines should be the right ones and proper administered to birds.
daniel severino Thanks for your nice comments. For sure, each region should evaluate the proper prime-boost vaccine strategy and choice the proper vaccines type for IBV according to the epidemiology of the region to obtain the proper protection.
Thank you for this self-explanatory work. In our breeder farm, we observed that Infectious bronchitis is endemic. At some point, we stock commercial broiler in some of our pen houses and sprayed them with IB4/91 at first week. We started experiencing facial swelling, sinusitis with respiratory distress and of course mild mortalities for like 2 batches. We removed the IB4/91 from the vaccination program for the 3rd batch and there was no sign of IB diseases on the farm.
Does it mean that IB4/91 vaccination done for the commercial broiler stocked for the first 2 batches failed or the birds had already been exposed to the field strain before the vaccination?
Akintunde Akintoye, greetings. Maybe the flocks sprayed with IB-4/91 had a bacterial infection and this vaccine its residual pathogenicity higher Classic IB vaccines, so it was a postvaccinal reaction complicated with bacteria. It's not preferable to use 4/91 in the first few days of life; if you are using prime-boost strategy; use it as a second dose; if it required in your area and match circulating virus, if not remove it from the vaccination program. Regards, Wael.
Wael Elfeil, greetings. thank you very much for your contribution. Just like you said, the vaccine strain isn't meant for priming. We have completely removed the vaccine from the vaccination program.
Akintunde Akintoye Dear sir first thank you for your message. Usually using 4/91 at first week when u have early IB challenge otherwise 2nd weeks is the recommended time. When u get post vaccination after using it, u need to be sure that you give it as coarse spray. Can you please let me know when you give it and what is the method?
Husam Bakri the vaccination was done first day of life using fine spray method. but after the post vaccination reaction , we removed the vaccine from the vaccination program totally.
Vaccine 4/91, was not originally developed for neonatal chickens, the reason is post-vaccination reactions. Confirmation of this, Early Issue Guidelines and MSD Recommendations for 4/91 Coarse Droplets 250-300 microns.
Well, but is it possible mutation in present situation though by applying vaccine starin H 120 strain its available in market but bacterial growth is controlled still mortality moves up waiting yr honourable opinion.
Fazal Malik Malik mutation risks in IB is high whatever the vaccines used
It can occur in nature with wild virus or even between wild virus and any vaccine seed
IB , belong to corona family, one of its main characteristic features is mutation and recombination
1. It is not possible To completely exclude the 793B group of vaccines from the priming of broilers for a day. You need to use for example (at 1day) Ibird793b+Mass. In the future (11-14 days) if you want to strengthen (increase strategy) 4/91+Mas(Ma 5). 2. H120-unfortunately loses its relevance. The reason is the deterioration of epizootics according to IBV
artsiom sereda
Based on Epidemiology of IB in your area
If you Have IB GI-13 , you can use 793b in the vaccination program
if your area dominate with GI-19, better to use QX
if your area dominate with GI-23, better to use Var2
Wael Elfeil
Thanks for useful discussion
I totally agree with you about when we use homologous vaccine against field strain ,they will induce good protection such as if we have Middle East strain we can use Var -2 vaccine but if we we have many serotype in field situation such as var-2 and QX I advice use protecotype theory to induce cross protection against other serotype
Kindly if you have technical study about efficacy of Var-2 vaccine against other heterologus IB strain of combined with classic or alone
Wonderful to learn about poultry vaccination. Does anyone of you have a vaccination schedule for kuroiler? Or any kind of commercial layers? Deogratius Nsanzugwanko
Deogratius Nsanzugwanko
the Broiler Vaccination program tailored based on the epidemiological situation and expected age of birds
please mention your epidemiological situation and condition of rearing and tailoring vaccination program , will be easier
Karnataka Veterinary, Animal and Fisheries Sciences University
21 de diciembre de 2020
I appreciate the scientists involved in this research. according to the local strains prevalent in the area and making vaccine is always useful and they work better in control of IB, it is our experience.
If we perform carcass surgery on chickens aged 6-7 weeks then we find fluid in the undeveloped oviduct on the right side, whether this is one of the signs of pathological symptoms due to after viral bronchitis infection or just normal conditions. Please enlighten me
Hi
Thanks for sharing information !
In the Middle East countries, usually poultry owners generally do no pay attention to biosecurity rules and do not follow them practically, therefore whatever vaccination program suggested and applied do not succeed! The field virus very rapidly multiplies and infect chicks before sufficient immunity developed against the disease which the vaccine were given (let say infectious bronchitis)!
Thanks
Oumed
@oumed gerjis Thanks Dear for valuable guidance. I have observed that poultry Farmers instead of working on bio security & other health management in long lived birds like commercial layer birds, give Live IB vaccines of both classic & variant types with the interval of 30 to 50 days. Only one type of vaccine is used at one time & is usually Massachusetts type but variant (usually 4/91 mostly is given as variant) after long intervals in comparison to Massachusetts.In my opinion it is more damaging due to nature of virus (Corona type) as it generates new variants or recombination of viruses for IB. Please guide about the interval for IB live vaccine repeat gap. Request is for all participants please
