Explore all the information onSwine gut health
Pigs are exposed to various challenges such as weaning, environmental stressors, unhealthy diet, diseases and infections during their lifetime which adversely affects the gut microbiome. The inability of the pig microbiome to return to the pre-challenge baseline may lead to dysbiosis resulting in the outbreak of diseases. Therefore, the maintenance of gut microbiome diversity, robustness and stability has been influential for optimum intestinal health after perturbations. Nowadays human and animal researches have focused on more holistic approaches to obtain a robust gut microbiota that provides protection against pathogens and improves the digestive physiology and the immune system.
The swine gut microbiome is a complex and dynamic ecosystem harboring immensely diverse microbiota including bacteria, viruses, archaea, and fungi that ideally reside symbiotically in the gut of host animals. Among the microorganisms, the number of bacteria outnumbers other microorganisms.
The microbiome robustness, the maintenance of diverse and functional microbiota in GIT is crucial for effective swine production. The microbiome robustness depends on the diversity of the microbiome, so it is not enough just to have the presence of a few different beneficial microbes. Accordingly, new strategies are required to manipulate the gut microbiome to prevent or revert unhealthy states caused by perturbations.
1. Introduction Weaning is one of the most challenging phases in a pig's life, often accompanied by reduced growth performance and increased incidences of diarrhea (Leibbrandt et al., 1975; VenteSpreeuwenberg et al., 2003). This phase is frequently characterized by reduced feed intake (Bruininx et al., 2002a; VenteSpreeuwenberg et al., 2003) which, in concert with an immature digestive and immune systems, predisposes the piglet to gastrointestinal disturbances. The major effects...
INTRODUCTION Gut health is a term increasingly used in the medical literature and by the food industry. It covers multiple positive aspects of the gastrointestinal tract (GIT), such as the effective digestion and absorption of food, the absence of gastrointestinal illness, normal and stable intestinal microbiota, effective immune status and a state of wellbeing (Bischoff, 2011). The GIT of a pig is a complex environment. Particularly in newborns and around the time of weaning,...
Introduction During the period of weaning transition, piglets are under a stressful condition that combined with nutritional, environmental, and immunological problems. Though antibiotics can apply to solve the poor situation of post-weaning, the concern about antimicrobial resistance to antibiotics enhances to find suitable alternatives to antibiotics. Probiotics are incorporated at the stage to maintaining intestinal ecosystem, enhancement...
Introduction Both humans and livestock are susceptible to high thermal loads that can cause acute, chronic, and lethal illness due to heat stress-related pathologies. In 2003, approximately 50,000 Europeans died during an intense heat-wave [1,2]. More recently, about 11,000 people succumbed to heat stress in Moscow during an abnormally hot 2010 summer [3]. Besides cooling and rehydration, there are few standard medical procedures to treat heat stroke and mortality for patients...
Implications This review provides relevant information on the utilization of dietary fiber (DF) by pigs and its effects on gut physiological functions, microbiota and health. This review delivers in-depth insight on both negative and positive effects of different fibers inclusion in swine diets. The DF lowers nutrient digestibility in swine. But, the fermentation of DF in the gut affects positively by modulating gut environment and potentially favoring ‘beneficial...
One of the most complex microbial ecosystems, which exists in our world is found within us human and all animals, namely in the gastrointestinal tract (GIT). The important role of gastrointestinal microflora in health and disease of animals and humans is...
Dr. Milena Sevastiyanova, Technical, and Commercial Manager Central Europe at Innovad, explains the results of some trials done in Europe in order to alleviate stress around the weaning, using Lumance®, during IPPE 2018, in Atlanta, USA...
Introduction Salmonella enterica serovar Typhimurium (S. Typhimurium) is a pathogenic Gram-negative bacterium of great clinical significance, responsible for foodborne zoonotic infections. The human disease is characterized by self-limiting gastroenteritis that occasionally can cause fever, systemic infection, and severe inflammation of the intestinal mucosal epithelium (Haagsma et al., 2008; Pires et al., 2011). ...
1. Introduction Morphine and other opioid receptor agonists alter systemic innate and adaptive immune responses and increase host susceptibility to infection [1]. For example, impairments in neutrophil function, macrophage phagocytosis, T lymphocyte cytokine production, and B cell antigen presentation occur after exposure to morphine. In some cases, these effects are mediated through mu-, delta- or kappa-opioid receptors (MOR, DOR, and KOR, respectively), transcripts...
Valeria Artuso, Swine Manager for Phytobiotics, explains some points about an Effective management and feeding strategies to promote gut health or limit intestinal inflammation using SANGROVIT®, during IPPE 2018, in Atlanta, USA...
Introduction Lactobacillus reuteri is a host-specific intestinal symbiont of humans and vertebrate animals (Walter, 2008; Frese et al., 2011). L. reuteri is commercially applied in cereal fermentations (Brandt, 2014) and as probiotic culture (Tuohy et al., 2003). Strain- or lineage specific metabolic traits of L. reuteri mediate host-specific colonization (Frese et al., 2014; Wilson et al., 2014), and contribute to its competitiveness in cereal...
Background Indigestible markers are commonly used in animal nutrition studies to calculate digestibility coefficients, with chromic oxide, titanium dioxide, and acid insoluble ash being the most common in swine research [1]. Physiological aspects associated with gastric emptying or rate of passage are complex and affected by a variety of factors [2, 3]. Rate of passage can be affected by BW [4], feed intake level [5], dietary fiber type and level [6–8], particle size [9],...
Introduction Enterotoxigenic Escherichia coli (ETEC) are a diverse group of pathogens that are characterized by the ability to colonize the small intestine while producing enterotoxins, which induce severe secretory diarrhea [1,2]. ETEC strains are recognized as one of the major causes of dehydrating diarrhea in children in developing countries and as an important causative agent of traveler’s diarrhea [3,4]. ETEC can also cause diarrhea in newborn calves and in...
Introduction Sunflower (Helianthus annuus, Asteraceae) is one of the most widely cultivated oil crops in the world (Flagella et al., 2002). The world-wild production of sunflower seed reached 37.08 million tonnes and subsequently produced 15.22 million tonne of oil (FAO, 2012). Together with soybeans, cottonseeds and canola (rapeseed), sunflower seeds are one of the major oilseeds produced in the world (Salunkhe et al., 1992). Oilseed by-products play an important role in...
Introduction Swine dysentery (SD) typically manifests as a severe mucohemorrhagic colitis arising from infection of the caecum and colon of grower-finisher pigs with the anaerobic intestinal spirochete Brachyspira hyodysenteriae [1]. SD can severely depress feed conversion efficiency, may require considerable antimicrobial use for its control, and represents an animal welfare issue. Strains of B. hyodysenteriae that are resistant to antimicrobial...
The intestinal mucosa possesses an extensive surface area and is exposed to a large and diverse number of microorganisms and potentially antigenic proteins throughout the lifetime of a pig. The mucosal epithelium is capable of assimilating vital nutrients while simultaneously excluding ingested pathogens and other harmful materials. In mature swine, an array of gastrointestinal defense processes act rapidly and collectively to intercept, neutralize or eliminate harmful antigens and microbes...
Dr. Christian Lückstädt, Technical Director for "Feed" business unit at Addcon, speaks about the mode of action of their 3rd generation acidifier based on a combination of Sodium diformate and glycerol monolaurate....
Gastrointestinal disorders remain a challenge to control and can severely affect the health and welfare of different animal species. Yet, plants produce an impressive array of compounds which can potentially be used as natural solutions to improve gut health. Tannins are widely spread in the plant kingdom and they are certainly an element of interest in this sense. Thanks to their antibacterial, antiviral or antispasmodic properties (Lupini et al., 2009), they have been traditionally...
Gut remodeling after weaning Heo et al. (2012) provide an excellent review of the gastrointestinal changes that occur in weaned pigs after weaning. As a brief summary of their review, the gastrointestinal changes at weaning include: Increased stomach gastric pH because of decreased acid secretion capacity and decreased lactic acid production due to lowered lactose intake. These changes may increase susceptibility of piglets to enteric infections at...
The gastrointestinal (GI) tract continues to undergo significant developmental changes in postnatal life. Environmental influences during this critical developmental period, including diet, stress and mucosal injury, have been shown to induce long-term changes in intestinal physiology and disease susceptibility in animal models(1 – 4). Similarly, in human subjects, increasing epidemiological evidence supports the concept that adverse early-life environmental factors, such as stress,...