Avian Influenza H9N2 and biosecurity - Husam Bakri

Why is this h9n2 showing up so often, when farms are getting closed that have outbreaks?
Also in the area that has Large groups of birds like geese. you don't find any dead birds there
Have any farms let this flu run its course? if not, why not as the bird is going to be killed in the end.

Dr. Husam Bakri is very right as we have also experienced all these problems in Pakistan.

We have acted 100% as Dr. Husam Bakri said & save the flock with a comprehensive vaccination program and a very high-level biosecurity whether there is disease or not. Once it enters in your area you have to be prepared to face it anytime, if it is not today, you never know when it will relapse. It is fact, if any viral disease is introduced in your area or region you have to be prepared to face it again anytime, so please do not relax.

The most professional that I have met (Dr. Husam Bakri) :)

Dr.Nimer Natsheh / JOVAC - Jordan:

Birds death at the end due to secondary infection either by bacteria or virus.

Regarding geese, no clinical signs appeared on the bird.

Recently research work that AIV - H9N2 vertically transmission to the geese progeny.

Regards

It's my observation that incident of AIV is low as compared to IBV and bacterial secondary invasion.
The complication occurs when no use of virus identification and isolation is done and on the basis of signs and symptoms, influenza is declared. One should conduct lab tests first, then claim diagnosis.

My fraternal salutations Dr. Husam Bakri
I have two interrogations.

Don't you think that much of the recrudescence of h9n2 will be genetic derivatives have always used a strain h9 / UAE / 99 whereas in countries is a genotype different from h9n2

I also want to try scientifically to understand how an inactive h9N2 vaccine can give us mucous immunity in sufficient trachea.

Thank you.

Great, Dr.
I need to ask you about H9N2 subtypes in our region.

Thanks for your answer but have seen in many countries uses new genotype h9N2 like Korea.
for my second question I want to say how an inactive vaccine that is made to induce IgG production could produce IGA antibodies to the tracheal mucosa that will protect us from H9N2 in the tracheal
thank you

Thank you, Dr. Wael Natsheh.
I want to know how an inactive product tracheal and intestinal iga is what you have a link or a publication that demonstrates this scientifically
if this is the case will have will not need for other diseases to use nebulization example during bronchitis will only use to inactivate it.
Thank you.

Hello Dr.

As you know the breeder DOC imported from Europe, esp France are not carrying any maternal antibodies against AIV; In countries like KSA what may be the initial strategy of immunization of such chicks.?
Further most authors claim that the HA of field and vaccine strain should be homologous to get the protection from the vaccine.Then how could we use a commercial vaccine which may not homologous with field? I need an answer as a technical expert and not as the representation of vaccine manufacturer.

Interesting lecture, but practitioners must take note that expectation for a successful immunization including vaccination against AI go beyond the mere process of the vaccination.
Our published studies with numerous post vaccination outbreak here in the tropics, had concluded that in vaccination for effective immune responses ,anti immuno- competent factors like overcrowding ,stress and mycotoxin must be strictly controlled
I will talk more of the need to manage immunological functions when we vaccinate against critical agents of viral infections like Mareks IBD and of recent against AI by ensuring that we use very broad spectrum toxin binder or in some cases the use of nanotechnology toxin binders that will bind or degrade or metabolise both small and large to toxins that can be found in chicken feed.
The major problem responsible for vaccination failure maybe the effect of large molecule toxins in causing on specific antibody production even when you have done a specific vaccination for ND and the host misbehaving to produce antibodies against infectious Bronchitis (IB).This phenomenon is referred to as a non specific antibody production which can be frequently seen in flocks that feed on DON of Fumonisin contaminated feed
Recent surveys showed that large molecule toxins occuring singularly or in mixed contamination are more prevalent even more that aflatoxin in animal feed,it is my view that each vaccination must be accompanied by feed with tolerable level of the large and small molecules mycotoxin ,while other potentiating factors must be strictly monitored within the period of two weeks of any critical vaccination

I totally agree with you about other diseases and biosecurity Dr. Husam. But I d like to add also the poor ventilation and high level of ammonia that can hurt the trachea and play the same rôle as IB or ND. That can be in part the explanation why the AI occurs strongly in the winter time in houses not equipped with ventilation system as they try to close the houses by fear of getting cold.