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A natural alternative to poultry growth promoters

PUBLICATION DATE:  24/12/2008
RATING
COMPANY:  PHODE S.A.
AUTHOR:  Virginie NOIROT - Courtesy of Phodé SA (Albi, France)

Following the ban on antibiotic growth promoters (AGPs) in Europe, various solutions have come on to the market, with more or less documentation. The objective of such solutions must be to ensure a level of efficacy at least equivalent to that obtained with the products they are designed to replace, while preserving the animals physiology in an environmentally-friendly manner. One of these solutions, based on plant extracts, essential oils and spices, has been developed for poultry production. Its objectives are to optimise feed intake and the digestive process as a whole to maximise feed utilisation, as well as to control pathogen development in the digestive tract. Today, this natural solution has proven its value and numerous trials on broiler chickens and turkeys validate this innovative concept. These trials, conducted either in research stations or on commercial farms, demonstrate that this plant-based complex (Oleobiotec®) helps to attain zootechnical performance similar to that obtained with antibiotic growth promoters, with a positive impact on poultry survival.


The complementary activities of essential oils and spices 

In all animal production, performance and health are closely linked to nutrition, but also to the efficacy of the digestive process, responsible for the conversion of raw materials by the animal. If we are able to optimise this process, we can contribute to optimising farm performance. Based on this idea, we have developed a specific blend of essential oils and spices aimed at enhancing and securing poultry digestive functions. Thanks to their complementary activities, these essential oils (oregano, thyme, cinnamon) and spices (ginger, turmeric, pepper...) are able to act at various levels of the digestive process (Figure 1).

Figure 1: The different levels of action of the Oleobiotec complex in poultry digestion.


Why use essential oils?

Today, the bactericidal activity of certain essential oils is well known and many scientific publications have investigated their modes of action. One of the principal modes of action of essential oils with bactericidal properties is directed against microbial membranes and cell walls. This specificity confers upon them a large spectrum of activity, targeting gram+ and gram- bacteria, yeast or fungus, unlike most of the traditional antibiotics. When added continuously to the feed, the essential oils contained in Oleobiotec can help secure the digestive process and control the potential pathogenic microflora present in the digestive tract.

In vitro studies have shown that the activity of Oleobiotec against the main pathogens affecting poultry, coliforms, Campylobacter, S. thyphimurium, C. perfringens, was comparable to the efficacy of commonly used antibiotics. (Figure 2).

Figure 2: In vitro bactericidal activity of Oleobiotec vs. antibiotics against some common chicken pathogens  (Laboratoire d'Hygiène Départemental du Tarn - France, 1999-2001)

 


Spices optimise the digestive process

In addition to their gustative qualities, spices are known for their effects on health and digestion. They are present in the traditional pharmacopoeia of many civilisations: chinese or ayurvedic medicine for instance. They were even used in Ancient Egypt for their medicinal properties. Today, many active compounds have been isolated from spices and characterised, such as piperine form peppercorn, 6-7-dihydrocapsaicin from pepper....Their modes of action are  increasingly known. The blend of spices present in Oleobiotec has been specifically formulated for its activity at different levels of the digestive process, from feed intake to nutrients absorption in the gut: 

  • 1) At the level of the taste buds: activation of the heat receptors, which in turn stimulate:

          - the salivation (increased synthesis of amylases)
          - the secretion of digestive juices in the stomach
          - the secretion of gastric juices and mucus by the stomach epithelium
          - the secretion of bile and increase in the level of biliary acids in the gastric juices  

  • 2) At the stomach level: increased gastric motility
  • 3) At the gut level: increased permeability of the gut mucosa to improve nutrient absorption. 

By optimising the digestive process, the blend of spices contained in Oleobiotec helps improve feed valorisation. 


Aromatic compounds to optimise ingestion

In order to optimise feed intake, some aromatic compounds were selected that have a positive impact on poultry.


Improved zootechnical performance in broiler chicken 

Various trials were conducted in broiler chickens, both in a research station and on production sites in different European countries.  Two meta-analysis were conducted: 

  • 1) In the first meta-analysis, the results of five trials with Oleobiotec were measured against the performance obtained with a growth promoter (avilamycine, 10 ppm ) -Table 1-.


Table 1: Details of the five trials used in the first meta-analysis

  • 2) The second meta-analysis compares the results of four trials with Oleobiotec against a negative control (table 2)



Table 2: Details of the four trials used in the second meta-analysis

 

Statistical analysis was performed using the linear mixed model on the Oleobiotec-control variations (program SPSS, version 13.0, 2004). The observed data was weighted according to the inverse of the variance of the difference. The fixed effect component is the constant and the random effect component is the experiment. The information criterion is the restricted maximum likelihood.

Results of the two meta-analysis are summarised in Tables 3 & 4 below.


Table 3: Conclusions of the first meta-analysis: zootechnical performance with Oleobiotec vs. a growth promoter.




The zootechnical performances obtained with natural solution Oleobiotec are similar to those attained with an antibiotic growth promoter.


Table 4: Conclusion of the second meta-analysis: zootechnical performance with Oleobiotec vs. negative control

 

The addition of Oleobiotec to the feed of broiler chicken significantly improves growth rate and slaughter weight when compared to control feed. 

 

Improved performance in turkeys

The results obtained in turkeys are similar to that of broiler chickens. Table 5 summarises the trial conditions and results for two experiments conducted in turkeys.

Figure 3 shows that Oleobiotec significantly increases turkeys live weight at twelve and twenty weeks, as compared to negative control or another feed additive based on essential oils.

When comparing Oleobiotec to negative control, some improvements were measured concerning the turkeys gastro-intestinal physiology: 

  • - a significant decrease of jejunal pH
  • - a numerical decrease of ileac digestas viscosity
  • - a significant increase of alpha-glucosidase enzymatic activity in the ilium (table 6). 

As observed with broiler chicken, Oleobiotec efficiency in improving performance and survival in turkeys is similar to that of antibiotic growth promoters.


Table 5 : Summary of two trials with Oleobiotec in turkey. (Phodé, 2005-2006)



Figure 3: Effects of various feed additives on turkeys' growth performance (Poultry Department of University of Warmia and Mazury in Olsztyn, Pologne).


Table 6: Effetcs of Oleobiotec on turkey's gastro-intestinal physiology (Poultry Department of University of Warmia and Mazury, Olsztyn, Poland)

 

 
Conclusion

It can be concluded from the results of these various trials that natural feed additive Oleobiotec, which combines the anti-bacterial properties of essential oils with that of the spices digestive qualities, enables  the enhancement of  growth performance in  turkeys and broiler chickens (ADWG and live weight at slaughter). It also improves feed efficiency, resulting in optimal feed valorisation. Various trials have permitted us to measure these effects against those of antibiotic growth promoters. Over the past few years, the European poultry production market has evolved, driven by various constraints, both economical and regulatory (AGPs withdrawal, Salmonella regulations...), whilst also having to meet consumer expectations. In such a context, Oleobiotec appears to be a profitable and sustainable alternative that naturally optimises poultry performance.

 

PUBLICATION DATE:  24/12/2008
RATING
COMPANY:  PHODE S.A.
AUTHOR:  Virginie NOIROT - Courtesy of Phodé SA (Albi, France)
 
AUTHOR DETAILS (Hide...)
Virginie Noirot
Animal Nutritionist
France - Midi-Pyrenees

RANK
 
17
PHODE S.A.
PHODE S.A.
Phone:00 33 563 77 80 60
- Midi-Pyrenees
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Professor
Egypt - Al Jizah
Rank
 
4
  12/29/2008
I think this concept of the use of spices extracts and essential oils will continue for some time and I think this will be the concept of tomorrow. We were reviewing many scientific papers specially from collegues from India, China and Egypt in the past 15 years and I think this is the time to harvest the outcome of these papers and apply it in the industry. Good Luck.

Dr. Fathy F. Mohamed.
Professor of Nutrition and Clinical Nutrition
Cairo University, Giza, Egypt.

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Ph.D in Poultry Production (Ostrich Farming)
Egypt - Ash Sharqiyah
Phone: 0020101278452
Rank
 
35
  ContactContact
This member offers his professional services Click here
  12/29/2008
Dear Sir,
Thank you so much for your article, it is a good effort from you.
I would like to inform you that herein Egypt, various studies were conducted on the effect of using the different materials (oregano, thyme, cinnamon) and spices (ginger, turmeric, pepper...) in the compound you mentioned to, and the researchers obtained a good results in this topic.
Thank you again.
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Technical Marketing Manager
Nigeria - ogun
Rank
 
26
Nigeria - Ogun
Phone: -
  ContactContact
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  12/30/2008
Honestly this is wonderful reseach, and I wish to congratulate you for the job well-done. However kindly ensure the availability of this product to farmers. We are using this media to tell you of our readiness to market this product in Nigeria.
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ibrahim ahmed
Doctor of Veterinary Medicine
Egypt - Al Jizah
Phone: 0101061232
Rank
 
35
  ContactContact
This member offers his professional services Click here
  01/27/2009
Dear sir,

Using of spices extracts and essential oils will be the concept of tomorrow.
We allready apply it in different fields (ducks- turkey- broilers), it gives more profit.

Thanks & best regards.
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Animal Nutritionist
India - Jammu and Kashmir
Rank
 
9
  02/02/2009
Dear sir,
I would like to hear about the availability of the product in India, and what are the natural sources of these essential oils which could have significant effect on the performance of broilers.
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Animal Nutritionist
Pakistan -
Rank
 
22
  04/01/2009
Scientific data based papers are always appreciated, therefore work done with future planning will be highly admirable.
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Dr. Justin Tan Yu-Wen
Doctor of Veterinary Medicine
Staff: Meriden Animal Health Limited
Malaysia - Selangor
Rank
 
43
United Kingdom - Bedfordshire
Phone: 44 - 1234 436130
  ContactContact
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  06/04/2009
Do essential oils really have an effect on optimising feed intake, especially at the level of the taste buds, since we know that chickens have very few taste buds?

Is there a significant increase in feed intake compared to a control group?
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Technical Manager
Staff: Phode
France -
Rank
 
17
- Midi-Pyrenees
Phone: 00 33 563 77 80 60
  ContactContact
ShowcaseShowcase   ContactContact
  07/29/2009
Thanks for your comments.
To answer some question : yes we have results and stimaulation of feed intake in broilers and other species.

In India and in Nigeria, we have not actually Distributors !
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amir attar
Animal Nutritionist
Iran - Tehran
Phone: +989155151135
Rank
 
52
  ContactContact
This member offers his professional services Click here
  08/20/2009
i think we wood better to use spices extracts and essential oils more. because thats better for people health.
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