Chris Morrow, Thank you so much for the explanation of the eye drop vaccination for mycoplasma and I appreciate it and will mandate it as a way of improving my layer's quality and health.
Regards,
Daniel.
Muhammad Kashif The live vaccines colonise the birds for life - you only need one vaccination. You should also vaccinate for MG and MS. MS can mimic anything MG can do.
ts-11 and MSH can be used from 3 weeks of age. Immunity may take 5 weeks to develop and you need to not use antibiotics after vaccination.
What is your opinion about F strain vaccination in layers?
it is an excellent vaccine for protection against MG with a good titer.
Chris Morrow due to commercial reasons if all the commercial layer farmers in an area can't adopt the M.g control strategy with M.g vaccine. A few farmers using M.g vaccine should adopt live M.g vaccine or killed M.g vaccine is the safest solution then?
Thanks for all the responses, on my farm I experienced some infections a year ago. I depleted made did a though clean up disinfected and then took a 3 month without stocking.
After that i stocked and my birds were doing very well. In the sixth week, I did vaccination using a live Mycoplasma MS. I did a repeat at 9th week.
A week ago I got an attack of the infection at age of 14 weeks. I have been treating and they have cleared. I first used Tiamulin for 3 days there was no effect at all the infection was just progressing. I have now controlled it . my problem why did I get this attack even after vaccinating .
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What should be the Multi-age commercial layer (M.g) control strategy?
1) you should control MG and MS with the same strategy. (freedom, vaccination, or antibiotics)
2) you should source replacement that is mycoplasma free
3) if your farm is multiage then you should rear stock remotely (2 km away from other poultry) and vaccinate them for the challenges they will get when they are moved to the multiage site.
4) Use live MG and MS vaccine - one dose. Don't use killed vaccines - don't worry about serology after vaccination and don't give the birds antibiotics unless they have clinical signs and if they do have clinical signs, get a diagnosis - DIVA PCR
Mycoplasma has been a problem to layer's farmers. How can eradicate it or prevent (consider to options). Preventing and controlling. How can we help to our best acknowledgment using our professional distinct.
Hello Dr. Chris
Is Ms live vaccinated flock getting PCR positive during rearing and production? If yes, that would be problematic in my country as we do not have laboratory equipped with sequencer to differentiate vaccinated from vaccinated infected flocks !!
Also it is so difficult to not to use antibiotics in Ms vaccinated flocks due to post vaccination reaction to other respiratory vaccines!
Your comments are highly appreciated!
Oumed
oumed gerjis MSH vaccinated flocks become MS PCR positive and stay that way for the life of the flock and this maintains immunity (also this is why you should not use routine/prophylactic antibiotics on flocks- the immunity will be impaired). If your lab can do PCR it can also differentiate MS field strains from MSH by PCR MAMAs (gel electrophoresis) that have been published (Kresinger et al).
The reluctance to stop antibiotics in MSH and MG ts-11 flocks shows a failure to understand what is the genesis of post vaccinal reactions. Viruses do not respond to antibiotic treatment. Post vaccinal reactions are worse and need treatment in Mycoplasma field strain (or F strain) infected flocks. If this infection is from vertical transmission you need to address it. Nearly everywhere in the world now you can get MG and MS free replacement stock. You can keep them free with Mycoplasma vaccination as long as you stop antibiotics.
Dear Dr Morrow,
Thanks
Do you think Using live Ms vaccine fails in areas where biosecurity is poorly practiced, impossibility to finding Ms and Mg free day old chick layers, over vaccination for Newcastle disease that leads to severe vaccination reaction followed by using antibiotics, multiple rearing of layer Pullets and producing layers in the same area?
Best regards
Oumed
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