IBV Variants in the Middle East

Published on: 09/05/2016
Author/s : Dr. Husam Bakri. / Technical and Pharmacovigilance, Manager, MSD Middle East - Dubai.

Introduction Infectious bronchitis (IB) virus, first described in the 1930s (Schalk & Hawn, 1931), continues to be a major cause of disease in chickens of all ages and types in all parts of the world (Anon, 1988, 1991). Good quality vaccines have been available to control IB infections since the 1950s. However, despite their careful use, IB continues to be a major problem. One reason for this...

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sawsan dabool sawsan dabool
Investigation and development
April 2, 2017
Hello

I want to know which IBV strains can we find in Syria, Iraq , Saudi Arabia, Jordan


thanks a lot
Reply
Husam Bakri Husam Bakri
Veterinary Doctor
April 2, 2017
Dear Sawsan ,
First thank you for your message . It has mentioned on my article, IB 4/91 , QX , Vart 2 , selumaneh , Iranian strains .

All the best

Bakri
Reply
sawsan dabool sawsan dabool
Investigation and development
April 3, 2017
thank you Dr Bakri
Reply
Mohamed Hassan Mohamed Hassan
Student
December 30, 2018
Dear Dr, Bakri

Thanks for your efforts. I would like to know about circulating IBV virus in UAE and If there were any proved results about presence of IS/1494/06 in UAE.

Thanks in advance.

M. Houta
Reply
Husam Bakri Husam Bakri
Veterinary Doctor
January 2, 2019

Dear Mohamed,
First, I would like to wish you a happy new year. On study showed that IS strain is present in our area in general also UAE.

Reply
Dr. Mohammad Akram Dr. Mohammad Akram
Consultant Microbiologist
January 3, 2019
Dear Brother Husam,
A very happy new year to you & all staff of MSD. I am agree with your suggestions to overcome the losses of IB Variants in Middle East.
Based on my long experience of working in Middle East and several knowledgeable discussion with you on this issue, I have applied the similar control measures in Karachi area of Pakistan.
For your kind information, many IB Variant unvaccinated commercial layer flocks without any drop in feed, apparently showing field exposure of unidentified IBV (Variant strains), resulted severe drop in egg production with deterioration of egg shell & egg albumen quality. P.M. examination showed lesions of FALSE LAYERS.
Single dose of live vaccine of IB (Ma-5 + 4/91) was given via drinking water route and almost one week post vaccination a remarkable increase in egg production & improvement in egg quality was noticed.
Best regards
Dr. M.Akram
Reply
Nguyen nhu nguyen Nguyen nhu nguyen
Doctor of Veterinary Medicine
January 5, 2019

Dr. Mohammad Akram
Dear Dr Akram,
As you mention, I would like to know that when did you apply ( Ma5+ 4/91)? At DO or when you saw clinical of false layer? Thanks

Reply
Dr. Mohammad Akram Dr. Mohammad Akram
Consultant Microbiologist
January 5, 2019
Dear Dr.Nguyen nhu nguyen,
Vaccine was applied during egg production at different age in different farms, based on the observation of signs & lesions of IB infection as mentioned in my comments. Regards
Reply
Husam Bakri Husam Bakri
Veterinary Doctor
January 5, 2019
Nguyen nhu nguyen : To get good protraction against IB infection from variants strains like QX you must give the vaccines at day one Mass+variants to avoid false layer during production. As soon I see this problem this means flock got the infection first 2 weeks
Reply
Nguyen nhu nguyen Nguyen nhu nguyen
Doctor of Veterinary Medicine
January 8, 2019
Husam Bakri thank you for your information
Reply
Kamalmousa Ghedan Kamalmousa Ghedan
Animal Health Technologist
January 14, 2019

dear dr. Husam
Greetings, 
Thank you
What's your opinion about QX vaccination?
Best regards

Reply
Husam Bakri Husam Bakri
Veterinary Doctor
January 16, 2019

Kamalmousa Ghedan, thank you for your question. As we have several IB variants challenging layer & breeder, using several IB variants strains before production will be great to protect birds and to be primier for killed vaccine and QX vaccine to be one from them will be good. Also, I advice to use the IB killed with different IB variants on it will give good antibodies, as more antibodies mean more protection during production.

Reply
January 29, 2019
Husam Bakri , if we use both IB classical and variant at one day old, we see alot of reaction. Why don't we move keep IB classical at day 1 and move variant to day 7 or 10? I saw alot CRD and another respiratory diseases of we do variant at day 1.
Reply
Husam Bakri Husam Bakri
Veterinary Doctor
January 29, 2019

Thanh,

First, thank you for your comments. The standard vaccination day for variants strains 14 days and the class one one day old. Using variants strain day one just when you are fasing IB probable at early age. To get good results from live respiratory vaccine make the interval between them at least 12 days.

Reply
January 16, 2019

Dr. What is the broiler breeder vaccine age of this vaccine?

Reply
Salah Mohammed Salah Mohammed
Biologist
January 16, 2019

Dear Dr. Husam, how could you explain the week immunity of IB whenever I used the combination of live Ma5 and clone 30 vaccine in my parent breeder?

Reply
Husam Bakri Husam Bakri
Veterinary Doctor
January 17, 2019

Dear salah ,
Thank you for your question. Can you please explain more what do you mean the week immunity?

Reply
Salah Mohammed Salah Mohammed
Biologist
January 17, 2019
Respected Dr Hisham greetings
Deeply sorry for that mistake I mean weak immunity that is to say the mean titre of IB is spare in amount Compare to that of ND
Reply
January 17, 2019
Sir, Good evening, How to identify the field strain and vaccine strain in modern lab.
Reply
Husam Bakri Husam Bakri
Veterinary Doctor
January 21, 2019

K.Balasubramanian First, thank you for your question and sorry for the late reply as I was traveling. Usually, we do PCR after we do sequencing here the most important to know is the vaccine strain sequence.

Reply
Dr Kibiike David Dr Kibiike David
Bachlor. Veterinary Medicine
January 18, 2019

The challenges I am getting, which may be similar to the above complaints, is that immunity is short lived and sometimes not there at all because many attacks have come in after several vaccinations have been done, and to make it worse these bacterial molecules become resistant to antibiotics very fast.

Reply
Dr Prafull Zade Dr Prafull Zade
MVSC VET PHARMACOLOGY
January 29, 2019

Can we give live vaccine in the IB outbreak in layers? And suppose which vaccine is suitable

Reply
January 29, 2019

Dr Prafull Zade, vaccine only for healthy birds, no vaccine company recommend for diseases birds. But in practice, we must know how many percent of the flock gets infection and the rest of the farm also. IB live vaccine will help if we do when the morbility still low and we want to protect the rest of farm. And if we do when the morbility too high, the farm will get more inflection. And it depends on what kind of IB vaccine you use, classical will respond immunity faster than variant.

Reply
Dr Prafull Zade Dr Prafull Zade
MVSC VET PHARMACOLOGY
January 29, 2019

Thanks Dr. for good suggestion.

Reply
February 23, 2019
Thanks Dr. Please is it advisable to mix IB and ND vaccines to administer to birds simultaneously?
Reply
February 23, 2019

You did all your vaccines correctly.
But found a viral disease.
There is no known medicament. Reason not known. maybe vaccine did not work. maybe the flock got it before the immunity is established?
Any spray will further distress the respiratory system. Any attempt to inject will spread the problem through the needle. The spread is slow and worrying daily with deaths and drop in production.
So what is left in doctor's hand. you spread it fast and it will end soon. Better you use an attenuated spread (vaccine) rather than the disease virus spreading slowly in vaccinated birds.

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