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Swine gut health

Pigs are exposed to various challenges such as weaning, environmental stressors, unhealthy diet, diseases and infections during their lifetime which adversely affects the gut microbiome. The inability of the pig microbiome to return to the pre-challenge baseline may lead to dysbiosis resulting in the outbreak of diseases. Therefore, the maintenance of gut microbiome diversity, robustness and stability has been influential for optimum intestinal health after perturbations. Nowadays human and animal researches have focused on more holistic approaches to obtain a robust gut microbiota that provides protection against pathogens and improves the digestive physiology and the immune system. The swine gut microbiome is a complex and dynamic ecosystem harboring immensely diverse microbiota including bacteria, viruses, archaea, and fungi that ideally reside symbiotically in the gut of host animals. Among the microorganisms, the number of bacteria outnumbers other microorganisms. The microbiome robustness, the maintenance of diverse and functional microbiota in GIT is crucial for effective swine production. The microbiome robustness depends on the diversity of the microbiome, so it is not enough just to have the presence of a few different beneficial microbes. Accordingly, new strategies are required to manipulate the gut microbiome to prevent or revert unhealthy states caused by perturbations.
In the quest for more productive animals, additives such as liquorice and peppermint are emerging as powerful tools in animal nutrition. These herbal ingredients offer a range of benefits, from improving digestion to supporting respiratory function, making them ideal supplements for optimising animal performance. By harnessing their unique...
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Surfactin is a powerful biosurfactant with significant potential in the livestock industry. It is renowned for its strong antimicrobial and anti-inflammatory properties, making it essential for enhancing animal gut health. By improving feed efficiency and boosting disease resistance, Surfactin plays a critical role...
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Darin Madson
Darin Madson and 1 more
Iowa State University
Iowa State University
Introduction: This study examined the effects of feeding Bacillus subtilis C-3102 (Calsporin® Calpis Co. Ltd., Japan) at the target inclusion rates of 0 CFU/g, 500 000 CFU/g and 1 000 000 CFU/g on intestinal health in weaned pigs after challenge with Porcine Epidemic Diarrhea virus (PEDv). Materials and Methods: A two by three factorial design composed of three diets containing 0 CFU/g or 500 000 CFU/g or 1 000 000 CFU/g of Calsporin® and PEDv...
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Ioannis Mavromichalis, a Ph.D. consultant in the animal nutrition industry, mentioned in Feed Strategy, "In my experience, feed prices always fluctuate. When they rise, the most effective way to maintain profitability is by enhancing the feed conversion ratio, or FCR." The Feed Conversion Ratio (FCR) is crucial in livestock farming as it significantly affects the cost per kilogram of meat. Feed costs can account for 40% to 70% of total production expenses, varying by country and type...
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Gerd Schatzmayr
DSM-Firmenich
Introduction: Antibiotics such as tetracyclines have been extensively used in swine production in the last decades. As a consequence, levels of antibiotic resistant bacteria in livestock have increased, which is discussed as major risk for public health. Thus, alternatives to antibiotics are urgently needed to reduce the amounts of antibiotics used in food producing animals. Natural feed additives, such as acids, phytogenics or pre/probiotics, are known to have a positive...
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Anna Rzasa
Wroclaw University of Environmental and Life Sciences - Polonia
Wroclaw University of Environmental and Life Sciences - Polonia
Introduction: They are several benefits of using IgY as a feed additive. Egg yolk or yolk plasma as a feed additive may improve the production results by two ways: 1) stimulation of growth rate through metabolism improvement and/or increasing feed intake; 2) stabilization and enhancing the gastrointestinal tract immune protection. The aim of the study was to compare two ways of IgY administration in the peri-weaning period (1 week before and 2 weeks after weaning) and to...
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Jens Peter Nielsen
University of Copenhagen ( DenmarK )
Introduction: Antimicrobial resistance testing of enterotoxic Escherichia coli (ETEC) is used as a diagnostic decision tool for selecting classes of antibiotics for treatment in pigs. Resistance testing is often done on isolates from faecal samples collected from diseased case pigs with the advantage of high certainty of analysing E. coli stains that has caused disease in the individual pig. The objective of this current study was to investigate pen-level...
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Introduction: After the first signals from the US about devastating PEDv infections in 2013, Europe was extremely motivated to prevent this virus crossing the Atlantic. A baseline study in the Netherlands, conducted in the second half of 2014, showed the naïve status of the Dutch pig industry for PEDv. In November 2014, after the first case of PED was confirmed by GD Animal Health, a PED taskforce, in which the government and all involved organizations in the Dutch pig...
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Ludovic Lahaye
JEFO Nutrition Inc.
Additives are part of the strategies for adding value to food, and their interest, in the current context of raw material prices, is even more evident. Nevertheless, there is a tendency to simplify their action to stick to the primary logic of their nature and easily generate an economic advantage. In doing so, we are likely to limit ourselves by failing to fully consider the scope of their work. In the case of the increasingly popular proteases, this involves a "simple" recovery of the...
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Eric Chevaux
Eric Chevaux and 2 more
Lallemand
Introduction: Saccharomyces cerevisiae boulardii is a probiotic yeast with an established history of use for the prevention and/or treatment of diarrhoea and chronic inflammatory disease in human medicine. More recently, S. boulardii has also been used in the pig industry to increase performance and reduce pathogen burden during vulnerable early life stages such as post-farrowing and weaning. Recent advances in DNA sequencing technology are now able to understand the host...
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Tobias Steiner
Tobias Steiner and 2 more
Agromed Austria GmbH
Introduction: Appropriate nutrient digestibility is a key to animal health and growth performance, particularly in post-weaning pigs. Compounds with anti-inflammatory or anti-oxidative properties have potential to support gut integrity and growth performance when included in diets for pigs. Isoquinoline alkaloids (IQ) derived from the Papaveraceae plant Macleaya cordata exert anti-inflammatory effects, whereas naringin (NRG), a bitter-tasting flavanone glycoside from...
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Josef Kamphues
University of Veterinary Medicine Hannover, Germany
University of Veterinary Medicine Hannover, Germany
Introduction: It is well known that stomach barrier (acidity) acts against diverse pathogenic agents. This function is particularly influenced by particle size distribution in the diet. Diarrhoea causing E. coli is an agent of relevance in today’s pig production that can lead to weight gains up to high losses. An experimental study was conducted to evaluate the ability of a specific pathogenic E. coli to survive stomach passage, in vivo and in vitro...
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Introduction: The effects of the oral supplementation of probiotics on the performance (weight gain and feed intake) and intestinal histo-morphology of the duodenal, jejunal, and ileal mucosa (villus height, width, and perimeter and crypt depth) of two different genetic lines (purebred Large White or crossbred Large White x Landrace) of suckling piglets. Materials and Methods: The suckling piglets were evaluated between 2 and 19 days of age. In total, 276...
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Introduction: Weaning process causes a significant biological stress to piglets which lead to a detrimental effect on feed intake, growth rate, intestinal morphology and immune system. A mixture of quaternary benzophenanthridine alkaloids and protopine alkaloids (QBA+PA) possess antimicrobial and anti-inflammatory effects. They also are known to improve endogenous digestive enzyme secretion, activate of the immune system and improve protein retention of farm...
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Jonathan Broomhead
Perstorp Feed & Food
Butyric acid is a short-chain fatty acid (SCFA) that is produced naturally by fermentation of fiber in the lower gastrointestinal tract (GI). Butyric acid has known benefits such as providing energy to colonocytes, intestinal barrier function, apoptosis regulation, control cytokine production, mucus synthesis, and intestinal cell proliferation, differentiation and maturation. Exogenous supplementation of butyric acid was initially developed by making a salt derivative, with either sodium or...
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Danyel Bueno Dalto
Agriculture and Agri-Food Canada
Agriculture and Agri-Food Canada
Despite environmental and public health (bacterial resistance) issues, supranutritional levels of zinc oxide (ZnO) are still commonly used to prevent diarrhea in post-weaning piglets. In Canada, these levels represent more than eight-fold the CFIA proposed maximum levels at 300 mg/kg. The limited knowledge of their consequences for the metabolism of trace minerals has hampered the replacement of this strategy without compromising piglet health. Our laboratory has performed a series of...
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Mycotoxins are secondary metabolites produced by fungi, the most abundant of which belong to the genera Aspergillus, Penicillium, and Fusarium . The conditions required for fungal development and the production of mycotoxins vary strongly with the substrate on which the fungal species develop.Because mycotoxins are mainly present in food and feed, the gut is the first target for mycotoxin toxicity, but it is also the site of the absorption of mycotoxins that leads to...
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Anita Menconi
Evonik Animal Nutrition
Evonik Animal Nutrition
The Specialty Nutrition portfolio for monogastrics overseen by Dr. Anita Menconi, Regional Business Director of Specialty Nutrition, Americas at Evonik, comprises advanced nutritional solutions tailored specifically for monogastric animals. ...
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John Patience
Iowa State University
Iowa State University
Basic Role of Feed Formulation Feed formulation is a process by which our knowledge of the nutrition of the animal can be translated into feeding programs which achieve our production objectives. These objectives typically include optimizing growth performance and producing a final carcass that can be converted into safe, healthy and appealing consumer meat products. This must be done in a profitable manner that concurrently contributes to environmental sustainability and animal...
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Young Dal Jang
University of Wisconsin River Falls
Young Dal Jang (University of Wisconsin–River Falls)       This study was conducted to demonstrate the effects of second iron injection before weaning and iron levels in nursery diets on growth performance, hematological parameters, and fecal microbiome of pigs. A total of 70 newborn pigs from 7 sows were allotted to 4 treatments within litter, housed in farrowing crate without creep feed, and received the first dose (200 mg iron) at 2 to 3 d of age....
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