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Swine gut health
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Nick Gallina (Purdue University) Background: Intestinal barrier dysfunction, inflammation, and elevated expression of heat shock protein 60 (Hsp60) are features of the dysbiotic gut. Probiotics can alleviate inflammation but are ineffective due to poor adhesion and adaptation to the inflamed bowel. We hypothesize that enhancing probiotic adhesion to intestinal cells may augment the immunomodulatory response, mucosal healing, and tight...
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Nick Gallina (Purdue University) Background: Enterotoxigenic Escherichia coli (ETEC) strains are the primary perpetrators of colibacillosis in piglets, resulting in mortality and agribusiness economic woes. ETEC expressing fimbrial antigens, F4 and F18, are the predominant contributors to colibacillosis. F4 is most prevalent in neonatal diarrhea. F18 is more common in post-weaning colibacillosis. Intestinal epithelial interaction and...
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Brian Aldridge (University of Illinois) Biological health is a complex topic of discussion and is often misunderstood as existing as a binary state in terms of the presence or absence of disease. In many ways, it is useful to explain health at a population or system level as the existence of individuals in 1 of 3 states: those in a healthy condition, those with a prediseased status, and those in a diseased state. At a systems level, it is useful to...
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Diana Ayala (Purina Animal Nutrition) Post-weaning diarrhea (PWD) is a serious health and welfare problem for the global swine industry. PWD is a multifactorial condition occurring the first 10–14 d after weaning; it is generally associated with the proliferation of pathogenic Escherichia coli groups, specifically enterotoxigenic E. coli (ETEC); however, PWD is also associated with several viral infections. Antibiotics are commonly used as a control...
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Yihang Li (University of Delaware) gives a presentation on the gastrointestinal tract and the impact of early life development on later life diseases in pigs, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
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Young Dal Jang (University of Wisconsin–River Falls) speaks on the microbiome of pigs and dietary iron levels, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
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Andrea Bonetti (University of Bologna) gives a presentation on botanicals and their impact on inflammation and oxidation, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
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Brian Aldridge (University of Illinois) shares insights on homeostasis and focusing on the host rather than the disease, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
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Nick Gallina (Purdue University) speaks on serotypes of E. coli in pigs, and presents studies aimed at developing more effective mitigation measures using cell models, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
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Caroline González-Vega (Cargill) presents research on the effects of a medium-chain fatty acid blend and a phytogenic feed additive on growth performance and gut health of Escherichia coli-challenged pigs, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
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Nick Gallina (Purdue University) presents research on probiotic adhesion to intestinal cells that may augment immunomodulatory response, mucosal healing, and tight junction restoration, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
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Diana Ayala (Purina Animal Nutrition) presents research to determine the underlying bacterial cause of PWD and a potential vertical transmission from sows to pre-weaned piglets, as well as to determine whether a customized direct-fed microbial (DFM)-based product could reduce the pathogens isolated from affected pigs, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
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Introduction: Plasma of porcine origin often contains PEDV RNA which raises some concerns about biosecurity and transmission of viruses within pig populations. In contrast, it is well recognized that the addition of plasma to pig feed enhances immune reactions and also has some intrinsic inhibition on virus survival. The objective of this study was to determine if there is any benefit to the diet containing spray-dried plasma (SDP) of bovine origin during acute PEDV...
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Introduction Zearalenone (ZEA) is a worldwide distributed mycotoxin as indicated by the International Agency for Research on Cancer (IARC). 1–3 Its toxicity and incidence was confirmed by recent reports. 4,5 This resorcylic lactone is produced mainly by Fusarium graminearum and is one of the most important toxins causing serious reproductive failures in pig production, due to its ability to couple 17--estradiol receptors. This interference with cytosolic...
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Wes Schweer (Cargill) talks about their impact on gut health, during this Swine It interview with host Laura Greiner....
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Dan Colombus (University of Saskatchewan) comments on increasing dietary fiber and its effect on gut health, during this Swine It interview with host Laura Greiner....
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Kathryn Price (Cargill) comments on gut health and dosing in swine nutrition, during this Swine It roundtable with Ken Mooney (Cargill) and host Laura Greiner....
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Phileo by Lesaffre has shown that feeding yeast (1.3)(1.6) beta-glucan Safglucan can help pigs cope better with the negative effect of enteric disorders caused by Lawsonia intracellularis. This is a new (patent pending) application for Safglucan to help the pork industry achieve profitable production while also reducing antimicrobial usage. Enteric disorders caused by L. intracellularis are often the source of reduced and heterogeneous weight gain, decreased feed...
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Potassium diformate is a strong acidifier that is released slowly in the digestive tract with high buffering properties, which prevents excessive fluctuations in the acidity of the gastrointestinal tract of animals. Studies have shown that 85% of potassium diformate passes through the pig’s stomach and enters the duodenum in its intact form. The...
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Introduction Maintenance of general health and prevention of infectious diseases are critically dependent on intestinal homeostasis and proper immune competence. In this regard, early colonization of the gut by microbiota as well as the concomitant development of the intestinal immune system has been proven to be important [1,2,3]. Immediately after birth, the intestine is colonized by bacteria derived from maternal and environmental sources [4,5]. During the early-life period, the...
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