Explore all the information onSwine gut health
Pigs are exposed to various challenges such as weaning, environmental stressors, unhealthy diet, diseases and infections during their lifetime which adversely affects the gut microbiome. The inability of the pig microbiome to return to the pre-challenge baseline may lead to dysbiosis resulting in the outbreak of diseases. Therefore, the maintenance of gut microbiome diversity, robustness and stability has been influential for optimum intestinal health after perturbations. Nowadays human and animal researches have focused on more holistic approaches to obtain a robust gut microbiota that provides protection against pathogens and improves the digestive physiology and the immune system.
The swine gut microbiome is a complex and dynamic ecosystem harboring immensely diverse microbiota including bacteria, viruses, archaea, and fungi that ideally reside symbiotically in the gut of host animals. Among the microorganisms, the number of bacteria outnumbers other microorganisms.
The microbiome robustness, the maintenance of diverse and functional microbiota in GIT is crucial for effective swine production. The microbiome robustness depends on the diversity of the microbiome, so it is not enough just to have the presence of a few different beneficial microbes. Accordingly, new strategies are required to manipulate the gut microbiome to prevent or revert unhealthy states caused by perturbations.
Mike Kogut, Chair of the Organizing Committee, talks about the meeting's most interesting discussions and announces the dates for the next edition....
INTRODUCTION Livestock monogastric species, including swine and poultry, are the main sources of meat; therefore, they are, at the same time, the main livestock species reared under intensive conditions (Eurostat, 2022). The pressure to increasingly optimize breeding resulted in antimicrobials often being used for both prophylactic and metaphylactic purposes to counteract the diseases of these animals or as growth promoters. It is currently commonly recognized that the misuse of...
Andrea Bonetti (University of Bologna) At weaning, pigs develop significant stress with long-lasting effects on their performance and health. Botanicals include a wide variety of bioactive molecules able to control inflammation and oxidation. The aim of the study was to investigate the ability of a microencapsulated thymol-based blend of botanicals (BOT) to support piglets’ performance and health during an LPS inflammatory challenge. To examine...
Yihang Li (University of Delaware) Developmental plasticity during the prenatal and early postnatal periods allows animals to adapt quickly to their environment and efficiently construct organ systems crucial for survival. These adaptations, which may be irreversible later in life, can lead animals to develop beneficial survival strategies or predispose them to chronic diseases. The gastrointestinal (GI) tract is a highly adaptive organ, contending...
Safglucan® – Mitigating the negative impact of Lawsonia intracellularis on pig performance and intestinal wellbeing. Phileo by Lesaffre has shown that feeding its yeast (1.3)(1.6) beta-glucan, Safglucan®, can help pigs cope better with the negative effect of enteric disorders caused by Lawsonia intracellularis. This is a new (patent pending) application for Safglucan® to help the pork industry achieve profitable production while also reducing antimicrobial...
Theresia Lavergne (Natural Biologics) comments on her research on the antiviral properties of medium-chain monoglycerides in pigs with PRRS challenge, as well as future tests on poultry viruses, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Brian Aldridge (University of Illinois) shares insights on the environmental, nutritional, and maternal factors that affect the microbiome of different animals, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Caroline González-Vega (Cargill) This study was conducted to investigate the effects of medium-chain fatty acid blend (MCFA) and a phytogenic feed additive (Fresta® Protect, Delacon, Austria) on growth performance and gut health of Escherichia coli (ETEC)-challenged pigs. A total of 200 weaned pigs with initial body weight of 5.52 ± 0.17 kg were allotted to 40 pens (5 pigs/pen) blocked by BW and randomly assigned to 5 treatments: (1)...
Nick Gallina (Purdue University) Background: Intestinal barrier dysfunction, inflammation, and elevated expression of heat shock protein 60 (Hsp60) are features of the dysbiotic gut. Probiotics can alleviate inflammation but are ineffective due to poor adhesion and adaptation to the inflamed bowel. We hypothesize that enhancing probiotic adhesion to intestinal cells may augment the immunomodulatory response, mucosal healing, and tight...
Nick Gallina (Purdue University) Background: Enterotoxigenic Escherichia coli (ETEC) strains are the primary perpetrators of colibacillosis in piglets, resulting in mortality and agribusiness economic woes. ETEC expressing fimbrial antigens, F4 and F18, are the predominant contributors to colibacillosis. F4 is most prevalent in neonatal diarrhea. F18 is more common in post-weaning colibacillosis. Intestinal epithelial interaction and...
Brian Aldridge (University of Illinois) Biological health is a complex topic of discussion and is often misunderstood as existing as a binary state in terms of the presence or absence of disease. In many ways, it is useful to explain health at a population or system level as the existence of individuals in 1 of 3 states: those in a healthy condition, those with a prediseased status, and those in a diseased state. At a systems level, it is useful to...
Diana Ayala (Purina Animal Nutrition) Post-weaning diarrhea (PWD) is a serious health and welfare problem for the global swine industry. PWD is a multifactorial condition occurring the first 10–14 d after weaning; it is generally associated with the proliferation of pathogenic Escherichia coli groups, specifically enterotoxigenic E. coli (ETEC); however, PWD is also associated with several viral infections. Antibiotics are commonly used as a control...
Yihang Li (University of Delaware) gives a presentation on the gastrointestinal tract and the impact of early life development on later life diseases in pigs, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Young Dal Jang (University of Wisconsin–River Falls) speaks on the microbiome of pigs and dietary iron levels, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Andrea Bonetti (University of Bologna) gives a presentation on botanicals and their impact on inflammation and oxidation, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Brian Aldridge (University of Illinois) shares insights on homeostasis and focusing on the host rather than the disease, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Nick Gallina (Purdue University) speaks on serotypes of E. coli in pigs, and presents studies aimed at developing more effective mitigation measures using cell models, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Caroline González-Vega (Cargill) presents research on the effects of a medium-chain fatty acid blend and a phytogenic feed additive on growth performance and gut health of Escherichia coli-challenged pigs, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Nick Gallina (Purdue University) presents research on probiotic adhesion to intestinal cells that may augment immunomodulatory response, mucosal healing, and tight junction restoration, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....
Diana Ayala (Purina Animal Nutrition) presents research to determine the underlying bacterial cause of PWD and a potential vertical transmission from sows to pre-weaned piglets, as well as to determine whether a customized direct-fed microbial (DFM)-based product could reduce the pathogens isolated from affected pigs, during the 11th Symposium on Gut Health in Production of Food Animals in St. Louis, USA....