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Viral diseases in poultry

If you ask poultry producers what damage viruses can do to their business, they will understandably think mostly about major diseases such as avian influenza, Gumboro disease or respiratory infections such as Infectious Bronchitis virus. However, this is merely the tip of the iceberg. Viral challenges can be the triggers for a whole range of problems which may never even appear as clinical disease but can have an even more devastating effect on overall flock performance, production and profits. They can affect one or more of the birds’ body systems, the most significant of which are the respiratory tract (lungs and air sacs), the skeletal system (bones and joints) or the intestinal tract (affecting gut function). Although other factors such as environment, nutrition and management play an important role in the full expression of diseases affecting these systems, the most significant underlying trigger is usually an infectious agent, and the most potent of these are undoubtedly viruses.
INTRODUCTION The bursa of Fabricius (BF) is a lymphoid organ, of lympho-epithelial structure. It is a site of B lymphocyte repertoire differentiation and maturation, located in the dorsal terminal part of the cloacae of the birds (Toivanen, et al 1987; Alloui & Sellaoui 2012). The BF is the essential (primary) target of Gumboro disease virus (IBDV). This disease manifests as acute and subclinical forms in chicks of age 0-3 weeks with immunosuppression or also in...
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Ayachi Ammar
Ayachi Ammar and 1 more
INTRODUCTION Inclusion body hepatitis (IBH) was first described in 1963 in the USA (Helmboldt and Frazier, 1963). Then after, the disease has been reported in many countries worldwide. It is a sporadic disease condition caused by several serotypes of fowl adenoviruses (Franco et al., 1974; Ferran, 2000; Fitzgerald, 2008; Gomis et al., 2006; Choi et al., 2012; Dar et al., 2012). The...
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Haroldo Toro
Auburn University
Auburn University
The commercial Saccharomyces cerevisiae fermentation product XPC™, often used as feed additive in poultry production, has been associated with enhanced immune functions. We evaluated immune responses and protection after IBV challenge in naïve and infectious bronchitis virus (IBV)- vaccinated specific-pathogen-free white leghorn chickens (groups n=50 each) receiving XPC at feed-additive concentrations of 2 lb/ton or 3 lb/ton. ...
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Holly Sellers
University of Georgia
University of Georgia
Dr. Holly Sellers (University of Georgia) speaks on viral diseases, prevention and control, during the 5th IHSIG Symposium on Poultry Intestinal Health in Bangkok, Thailand....
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HI there, We are facing a complex disease situation in most of the areas of Pakistan, which is of respiratory in nature showing redness of trachea with mucus and fibrinous plugin bifurcation, MG growth over lungs, yellow to white diarrhoea with mortality of 10% to 50% and morbidity starts from fan side of control sheds surprisingly leaving the pad area birds with very light infection, morbidity and mortality. After three days this disease transfers towards pad areas and after another 3 days...
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Dr. Brian Jordan
University of Georgia
University of Georgia
Brian Jordan (University of Georgia) talked about the Ark99 strain and what was found out during the investigation, regarding mutations in the genome, during IPPE 2018 in Atlanta, USA....
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Mohamed.Amine BOUDERBAL
Ceva Animal Health
Introduction: The purpose of this study was to demonstrate the presence of virus disease of infectious Laryngotracheitis (ILT) in Algeria in laying hen farms; through the demonstration of seroconversion signing a recent viral passage and also a comparative study cost / benefit of vaccination against this disease. Up ‘til 2011, no study was conducted to highlight the presence of the...
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Dr Venugopal Nair
Imperial College London
Introduction All known viruses share an absolute requirement for host cell ribosomes and are exquisitely dependent on cellular translation factors to meet their synthetic needs. Faced with this dependency, viruses have evolved strategies to commandeer the host translational apparatus [1, 2]. Studies of viral subversion of host protein synthesis machinery have not only revealed key steps in viral pathogenesis, but also...
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Pedro Villegas
Pedro Villegas and 3 more
University of Georgia
University of Georgia
Infectious bronchitis (IB) is a globally distributed avian disease that represents one of the most persistent sanitary problems to the commercial poultry industry. The intensive production of high-density bird populations promotes IB transmission and, in spite of intensive control programmes, outbreaks are extremely frequent in commercial flocks (USDA, 2014). The aetiological agent of IB is the infectious bronchitis virus (IBV), belonging to the genus Gammacoronavirus within...
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Introduction Avian leucosis virus (ALV) is belonging to the family Retroviridae, subfamily ortho retrovirinae, genus Alpha retrovirus. Exogenous avian leucosis viruses(ALV) are classified into A,B,C,D and J subgroups based on their host range, cross neutralization and viral interference. They can induce different path types of neoplastic diseases in chickens (Fadly and Payne. 2003). Among these subgroups, subgroup J,A...
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Dr Venugopal Nair
Imperial College London
Introduction Cytosines within the genome not only constitute part of the genetic code but are also amenable to chemical modification making them a central conveyer of epigenetic information. Methylation of the fifth position of cytosine (5-methylcytosine, 5mC) is an evolutionarily conserved epigenetic modification [1] which helps to maintain genome stability and acts as a suppressive mark for gene expression [2]. It is...
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Dr Venugopal Nair
Imperial College London
  1. Introduction MicroRNAs (miRNAs) are ~22-nucleotide small RNA molecules that profoundly affect gene expression by directing repressive protein complexes to the untranslated region (UTR) of target messenger RNA (mRNA) transcripts. Since its first discovery in C. elegans [1], identification of miRNAs, some of which are evolutionarily conserved [2–4], has continued at a fast...
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Dr Venugopal Nair
Imperial College London
To date, the vast majority of known virus-encoded microRNAs (miRNAs) are derived from polymerase II transcripts encoded by DNA viruses. A recent demonstration that the bovine leukemia virus, a retrovirus, uses RNA polymerase III to directly transcribe the pre-miRNA hairpins to generate viral miRNAs further supports the common notion that the canonical pathway of miRNA biogenesis does not exist commonly among RNA viruses. Here, we show that an exogenous virus...
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Faizal Abdul-Careem
University of Calgary
University of Calgary
  1. Introduction TLRs and their downstream signaling components are mostly conserved in chickens (Lillehoj and Li, 2004; Lynnet al., 2003; Philbin et al., 2005), except for TLR4 (Keestraand van Putten, 2008). In mammals, TLR4 is expressed in a variety of immune and non-immune cells (Arpaia et al.,2011; Tang et al., 2008). One of the well-characterized ligands that binds with TLR4...
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Martha Pulido-Landínez
Mississippi State University
Mississippi State University
Martha Pulido-Landinez, Professor at Mississippi State University, talked about the appearance of Astrovirus and Reovirus in chickens, their impact on health and factors that can cause Salmonella and Campylobacter, during IPPE 2017 in Atlanta, USA....
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Gary Butcher
University of Florida
University of Florida
WHY VACCINATE? Vaccination is an effective means to prevent and/or reduce the adverse effects of specific diseases in poultry. Poultry refers to birds that people keep for their use, and generally includes chicken, turkey, duck, goose, quail, pheasant, pigeon, guinea fowl, pea fowl, ostrich, emu and rhea. Disease-causing organisms can be classified, smallest to largest, as viruses, mycoplasma, bacteria, fungi, protozoa, and parasites....
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Travis Schaal, GP and Technical Manager at Hy-Line, spoke about avian influenza, his experience during an outbreak and recommendations to prevent this disease. His lecture took place during the Poultry and Egg Summit Latin America VIV 2016 in Buenos Aires, Argentina....
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Gumboro Disease or Infectious Bursal Disease (IBD) is one of the most common diseases of commercial poultry in Asia. In the clinical acute form (vvIBDV), the disease causes significant economic losses due to mortality, reduced performance and immunosupression that lead to increased susceptibility to other diseases. The IBD virus is extremely resistant to environmental conditions and chemicals. Therefore the control of the disease must take into consideration strict biosecurity combined with...
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Guillermo Zavala
University of Georgia
University of Georgia
Infectious laryngotracheitis (ILT) is a highly contagious respiratory disease of chickens and is responsible for significant economic losses in the poultry industry worldwide; it is caused by Gallid herpesvirus-1 (GaHV-1), commonly known as infectious laryngotracheitis virus (ILTV). In the United States the disease is controlled by vaccination with live attenuated vaccines, recombinant viral vector vaccines, or both (7). Experimental evaluation of ILTV...
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