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Swine enteric diseases

Enteric diseases, including ileitis, salmonellosis and porcine epidemic diarrhea (PED), are common gastrointestinal disorders that, if left untreated, can result in undernourished, dehydrated pigs and possible death. Pigs of all ages are susceptible to intestinal diseases, and diarrhea is the clinical sign common to nearly all such disorders. Infectious agents that cause enteropathies are typically transmitted via the fecal-oral route. More than 20 etiologic agents, including bacteria, viruses, and parasites, can cause primary intestinal disease in pigs. Some other viruses, including sapovirus, adenocirus, and enterovirus, also have been isolated from the intestines of pigs but are not associated with economically consequential disease. Pig diarrhoea is one of the most frequent health problem in modern production, which can be associated with high mortality, decreased growth rates and an increase in treatment costs. The solution for an enteric disease requires a diagnosis which is based on diagnostic criteria, that must be respected to be reliable. The veterinary practitioner has the responsibility of making a final diagnosis, and based on this to make decisions concerning the management of swine health problems. The veterinary diagnostic laboratory can be an important support providing technical assistance in performing laboratory testing and consultancy activity.
Marina Kamoei
MSD - Merck Animal Health
Marina Kamoei (Merck Animal Health) discussed ileitis and the impact of intestinal diseases on production, during IPVS2022 in Rio de Janeiro, Brazil....
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Frédéric Vangroenweghe (Elanco Animal Health) demonstrated the efficacy of an oral live non-pathogenic E. coli F4/F18 vaccine (Coliprotec®) for active immunization of piglets against post-weaning diarrhea, during IPVS2022 in Rio de Janeiro, Brazil....
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Dr. Laura Greiner
Iowa State University
Iowa State University
Wes Schweer (Zinpro) talked about different treatment and management situations when this occurs, in this Swine It interview with host Laura Greiner....
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Charlotte Lauridsen
Aarhus University, Denmark
Aarhus University, Denmark
Introduction Post-weaning diarrhoea ( PWD ) is a significant enteric disease causing considerable economic losses for the pig industry. Among several etiological risk factors, enterotoxigenic Escherichia coli ( ETEC ) is considered to be a major cause, i.e. colibacillosis. The use of antibiotics at subtherapeutic concentrations was routinely used as growth promoters for several decades, but has since 1 January 2006 been banned in the European Union due to the...
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Introduction: Brachyspira pilosicoli is the etiologic agent of porcine colonic spirochetosis, a diarrheal disease in growing pigs. Colitis associated with Brachyspira pilosicoli is less severe than swine dysentery caused by Brachyspira hyodysenteriae , however, antimicrobial therapy is needed on some farms to treat diarrhea in weaners and in young finishing pigs. According to principles of prudent use of antimicrobials, only effective drugs should be...
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Roberto Maurício Carvalho Guedes
Universidade Federal de Minas Gerais - UFMG
Universidade Federal de Minas Gerais - UFMG
Introduction: Brachyspira hyodysenteriae is the primary etiologic agent of Swine Dysentery. The disease causes severe mucohaemorrhagic diarrhoea, and thereby severe economic losses to swine production. This study aimed to evaluate the genetic diversity, epidemiology and phylogeny among Brazilian isolates of B. hyodysenteriae obtained from outbreaks in 1990s and from 2011 to 2015. Materials and Methods: Forty-eight Brazilian isolates of...
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Introduction: Outbreaks of bloody diarrhea in swine herds in the late 2000s signaled the re-emergence of swine dysentery in the U.S. Diagnostic investigations confirmed the emergence of a novel pathogen “ Brachyspira hampsonii ” with two distinct genetic groups circulating in U.S. swine. It has since been detected in swine and migratory birds in North America and Europe. Objective: The aim of this study was to develop and implement a...
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Introduction: Enteric infections cause economic losses in pig production. Increases in costs are associated with reduced average daily gain (ADG), increased mortality rate and increased in use of antibiotics. Porcine proliferative enteropathies (PPE), swine dysentery (SD), porcine spirochetosis and salmonellosis are enteric diseases caused by L. intracellularis (LI), B. hyodysenteriae (BH), B. pilosicoli (BP) and Salmonella enterica ...
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Introduction: Brachyspira spp. are a group of enteric pathogens prevalent worldwide in most swine rearing geographies. To determine appropriate therapy for Brachyspira disease, minimum inhibitor concentrations (MIC) of antibiotics are a common first step. Narasin is a recently FDA approved ionophore antibiotic to improve growth in swine in the USA. The objective of this study was to determine the MIC of tiamulin and narasin using Brachyspira isolates from clinical...
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Pedro Rubio Nistal
Universidad de Leon - España
Universidad de Leon - España
Introduction: Brachyspira hyodysenteriae is the aetiologic agent of swine dysentery (SD), an infectious disease that affects growing and fattening pigs causing severe bloody diarrhoea and haemorrhagic colitis. Brachyspira pilosicoli causes a non-fatal and non-bloody milder catarrhal colitis named porcine intestinal spirochaetosis (PIS) in young pigs. Our purpose has been to determine the prevalence of these two spirochaetes in Spanish farms with...
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Joel Nerem
Joel Nerem and 2 more
Pipestone
Pipestone
Background Porcine epidemic diarrhea virus (PEDV) is an enveloped single-stranded positive sense RNA virus belonging to the Order Nidovirales, the family Coronaviridae and the genus Alphacoronavirus (Saif et al. [1]). Following detection in the US swine population during May, 2013, the virus spread rapidly across the country and 6317 cases of Porcine Epidemic Diarrhea (PED) have been confirmed in 29 states as of May 3, 2014 [2,3]. While little information is known regarding the...
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Ana Carvajal
Ana Carvajal and 1 more
Universidad de Leon - España
Universidad de Leon - España
Introduction: The antibiotic resistance of field strains of Brachyspira hyodysenteriae has increased in the last years in Spain as well as in other countries due to the high use of antibiotics for the control of swine dysentery (SD). For this reason, antimicrobial susceptibility tests are becoming essential for an effective control of this disease. Our objective was to study the antibiotic susceptibility of Spanish field strains of Brachyspira hyodysenteriae in...
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Introduction: Cystoisospora (syn. Isospora ) suis is a leading cause of diarrheal disease in neonatal piglets and the disease is related to considerable economic losses. The metaphylactic treatment with toltrazuril 3 to 5 days after birth is a common control measure practiced in many countries. Another essential practice is the prevention of neonatal iron deficiency anaemia as piglets are born with small iron reserves (35 to 50 mg) and sow milk contains...
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Bob Goodband
Bob Goodband and 7 more
Kansas State University
Kansas State University
Introduction Porcine Epidemic Diarrhea Virus (PEDV) is an enveloped single-stranded positive-sense RNA virus that was first identified in the United States in May 2013. Epidemiological and controlled experiments have shown that complete feed or feed components can be one of many possible vectors of transmission of PEDV. 1 Previous research has shown that a 2% and 1% mixture of caproic, caprylic, and capric acids can reduce the risk of PEDV in a complete swine diet....
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Olena Ayshpur
Institute of Veterinary Medicine
Introduction Ileitis (proliferative enteropathy of pigs), caused by the obligate intracellular parasite, the bacterium Lawsonia intracellularis, is the most common intestinal infection worldwide, affecting piglets in the rearing and fattening pigs. Arnold et al. (2018) detected a whole group of pathological changes in the small intestine. The disease occurs in four different forms, namely: regional ileitis, intestinal adenomatosis, hemorrhagic enteropathy, necrotic enteritis. It...
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Swine dysentery (SD) caused by Brachyspira hyodysenteriae is a highly contagious disease of grower and finisher pigs. SD causes severe mucohemorrhagic diarrhea, resulting in decreased feed efficiency and increased morbidity. Necrotic enteritis (NE) caused by Clostridium perfringens is characterized by high mortality in poultry with bloody diarrhea, and sudden death. B. subtilis and B. licheniformis have been identified from the gastrointestinal tract of...
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Cordyceps militaris is a rare and exotic Chinese medicinal mushroom. Cordyceps militaris is widely used as a tonic for vitality and longevity for thousands of years by the Chinese. Cordyceps militaris has been used for a long time as a nutraceutical food in Korea and Japan. Easy-immune contains cordycepin and polysaccharides from Cordyceps as natural immunity booster. The medical potential of the metabolites of Cordyceps militaris has been widely...
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Bob Goodband
Bob Goodband and 9 more
Kansas State University
Kansas State University
Introduction Porcine Epidemic Diarrhea Virus (PEDV) is an enveloped single-stranded positive-sense RNA virus that was first identified in the United States in May 2013. Epidemiological and controlled experiments have shown that complete feed or feed components can be one of many possible vectors of transmission of PEDV. Because of the potential viral spread by feed and ingredients, reduction techniques such as chemical treatments have been used to combat the virus. Many chemical...
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Cordyceps militaris is a rare and exotic Chinese medicinal mushroom. Its chemical composition and pharmacological effects are similar to C ordyceps sinensis . Cordyceps sinensis is widely used as a tonic for vitality and longevity for thousands of years by the Chinese. Cordyceps militaris has also been used in Chinese medicine for thousands of years. Easy-immune contains cordycepin and polysaccharides from Cordyceps as a natural immunity...
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