Dr. Tanja Opriessnig

Introduction:Parvoviruses have been circulating in the global pig population for some time. So far, six porcine parvoviruses have been described in pigs including the classical PPV1 commonly associated with reproductive failure in breeding herds and newly recognized PPV2, PPV3, PPV4, PPV5 and PPV6. An association of porcine circovirus type 2 (PCV2) and PPV1 (also known as the classical PPV) or the ...

Introduction: Influenza A virus (IAV) is economically important in pig production and has broad public health implications. Because of public health concerns, some geographic areas have IAV monitoring in swine initiated. In Europe, active IAV surveillance includes demonstration IAV RNA in nasal swabs or oral fluids and/or demonstration of antibodies in serum (SER) samples; however, collecting appr ...

Introduction:Plasma of porcine origin often contains PEDV RNA which raises some concerns about biosecurity and transmission of viruses within pig populations. In contrast, it is well recognized that the addition of plasma to pig feed enhances immune reactions and also has some intrinsic inhibition on virus survival. The objective of this study was to determine if there is any benefit to the diet c ...

Introduction:PCV2a is the longest known PCV2 genotype and the current commercial vaccines contain PCV2a. In recent years PCV2b has been the main strain identified in field cases in the US. Since 2012, PCV2d has been associated with apparent PCV2 vaccine failures in the US. In a large study investigating PCV2 sequences from 2012-2013 in the US, 37% of all 143 sequences investigated were classified ...

 Big liver and spleen disease or hepatitis splenomegaly syndrome (HSS) is clinically characterized by increased mortality and decreased egg production in both broiler breeder hens and egg-type chickens, usually ranging from 30 to 72 wk of age. On gross examination, blood-tinged fluid can frequently be observed in the coelomic cavity, and liver and spleen are typically both enlarged (19).  ...

Opriessnig T, Xiao C-T, Gerber PF, Zhang J, Halbur PG (2014) Porcine Epidemic Diarrhea Virus RNA Present in Commercial Spray-Dried Porcine Plasma Is Not Infectious to Naïve Pigs. PLoS ONE 9(8): e104766. doi:10.1371/journal.pone.0104766Received: June 16, 2014; Accepted: July 15, 2014; Published: August 12, 2014Tanja Opriessnig, Priscilla F. Gerber (The Roslin Institute ...

The pathogenesis of porcine circovirus type 2 (PCV2) infections in pigs is still not completely understood. PCV2 has a tropism for lymphoid tissues where it is associated with depletion of follicles and histiocytic infiltration thereby accumulating in large numbers mainly in the cytoplasm of macrophages (1).PCV2 belongs to the Circoviridae family and is one of the smallest known single-stranded DN ...