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Introduction: Enteric infections cause economic losses in pig production. Increases in costs are associated with reduced average daily gain (ADG), increased mortality rate and increased in use of antibiotics. Porcine proliferative enteropathies (PPE), swine dysentery (SD), porcine spirochetosis and salmonellosis are enteric diseases caused by L. intracellularis (LI), B. hyodysenteriae (BH), B. pilosicoli (BP) and Salmonella enterica ...
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Introduction: Brachyspira spp. are a group of enteric pathogens prevalent worldwide in most swine rearing geographies. To determine appropriate therapy for Brachyspira disease, minimum inhibitor concentrations (MIC) of antibiotics are a common first step. Narasin is a recently FDA approved ionophore antibiotic to improve growth in swine in the USA. The objective of this study was to determine the MIC of tiamulin and narasin using Brachyspira isolates from clinical...
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APIs and Vitamin MARKET - The weak demand for the APIs
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Introduction: Brachyspira hyodysenteriae is the aetiologic agent of swine dysentery (SD), an infectious disease that affects growing and fattening pigs causing severe bloody diarrhoea and haemorrhagic colitis. Brachyspira pilosicoli causes a non-fatal and non-bloody milder catarrhal colitis named porcine intestinal spirochaetosis (PIS) in young pigs. Our purpose has been to determine the prevalence of these two spirochaetes in Spanish farms with...
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Introduction The use of enzymes in modern non-ruminant production has become universal. This is due to the extensive benefits observed on the productivity of both poultry and swine with its use. Although most feed ingredients used in monogastric nutrition contain adequate nutrients, monogastric animals are not able to efficiently utilize all the nutrients present in these ingredients. This has been attributed to several factors including the presence of antinutritional factors...
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Immunometabolism is the study of immunity and metabolism as an integrated system. The prototypical organ for such study is the gut. Central to the proper and optimum functioning of the gut, thus its immunometabolism, is the microbiota. Often the microbiota is considered only in the context of what functions, molecules and signals it provides to the host. However, the interactions between the host and microbiota must fundamentally be understood as bidirectional communication. In the realm of...
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Background Porcine epidemic diarrhea virus (PEDV) is an enveloped single-stranded positive sense RNA virus belonging to the Order Nidovirales, the family Coronaviridae and the genus Alphacoronavirus (Saif et al. [1]). Following detection in the US swine population during May, 2013, the virus spread rapidly across the country and 6317 cases of Porcine Epidemic Diarrhea (PED) have been confirmed in 29 states as of May 3, 2014 [2,3]. While little information is known regarding the...
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Cordyceps militaris hot water extract inhibits lipopolysaccharide-induced inflammatory response in porcine alveolar macrophages by regulation of mitogen-activated protein kinase signaling pathway
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INTRODUCTION According to new concepts about human health and increase on protein demand there was significant improvement in carcass quality of pigs to supply market which seeks a pork lean meat. Thus, it should be considered some conditions that impose changes in nutritional requirements of pigs, such as genetic potential for meat production, gender and age for maximal performance. Amino acid levels in most of diets are recommended from the data reviewed (National...
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Introduction: There are two registered vaccines available (Clostriporc A, Enteroporc A, IDT Biologika GmbH) to prevent suckling piglet diarrhea caused by Clostridium perfringens type A (CpA). These are based on the α- and β2-toxoids. The goal of this study was to evaluate the development of antibodies against the α- and β2-toxins after recurrent vaccination of gilts with ENTEROPORC A under laboratory conditions. Materials and...
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Lesaffre has completed the acquisition of dsm-firmenich’s yeast extract business
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Let’s talk about Guanidinoacetic acid (GAA), Part II. In this video, Lukas Bauer, Manager Technical Consultancy for GuanAMINO® at Evonik Animal Nutrition, speaks about the importance of Guidenoacetic Acid (GAA) and the sustainability that offers for the animal nutrition industry...
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Introduction: The antibiotic resistance of field strains of Brachyspira hyodysenteriae has increased in the last years in Spain as well as in other countries due to the high use of antibiotics for the control of swine dysentery (SD). For this reason, antimicrobial susceptibility tests are becoming essential for an effective control of this disease. Our objective was to study the antibiotic susceptibility of Spanish field strains of Brachyspira hyodysenteriae in...
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Introduction: Mesocolon edema syndrome is recognized as a common cause of diarrhea in pigs less than 2 weeks of age, and has been associated with neonatal colonization by Clostridium difficile , C. perfringens , or often as a combined infection. In the United States, C. perfringens type A is increasing in prevalence, but C. difficile colonization and subsequent enterotoxemia is still an important cause of the syndrome. In this study, we directly...
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APIs and Vitamin MARKET - The weak demand for the APIs
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Introduction: Infection with C. difficile may have subclinical signs and light manifestations of disease; its transmission is fecal-oral route, considered as the principal way of contamination. As bacterial infections have negative impact, on the roster, this study has relation with the ways of transmission of C. difficile in swine. This study was to evaluate the transmission of C. difficile via aerogen using PCR and histological section of...
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Introduction: Clostridium perfringens type A enteritis is a frequent disease of the newborn piglets with a major economic impact in the Czech Republic and important swine producing countries as well. Different antimicrobials may be used for treatment of piglets affected by clostridial enteritis. There are only a few reports on antimicrobial susceptibility of C. perfringens from pigs. Overall, the most common resistance in C. perfringens is to...
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Introduction: Cystoisospora (syn. Isospora ) suis is a leading cause of diarrheal disease in neonatal piglets and the disease is related to considerable economic losses. The metaphylactic treatment with toltrazuril 3 to 5 days after birth is a common control measure practiced in many countries. Another essential practice is the prevention of neonatal iron deficiency anaemia as piglets are born with small iron reserves (35 to 50 mg) and sow milk contains...
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Introduction: The purpose of this study was to demonstrate the economic benefit and improved yield of groups of gilts vaccinated with SUISENG®, on a farm with a high prevalence of neonatal diarrhoea caused by E.coli/Clostridium . Materials and Methods: 49 clinically healthy, PRRSV-positive and ADV-negative gilts were selected on a farm with 800 sows, and divided into 4 groups, 2 vaccinated (V1 n=13; V2 n=12) and 2 not vaccinated (NV1 n=12;...
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Cordyceps militaris hot water extract inhibits lipopolysaccharide-induced inflammatory response in porcine alveolar macrophages by regulation of mitogen-activated protein kinase signaling pathway
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Introduction: Clostridium perfringens is a gram-positive bacteria that can cause diarrhea and is commonly transferred from the sow to the piglet. The objective of this study was to evaluate dietary addition of a Saccharomyces cerevisiae fermentation product during late gestation through a 21 d lactation on sow and litter performance, milk components, and fecal Clostridium perfringens. Materials and Methods: On d 93 of...
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INTRODUCTION Phosphorus is an essential mineral for the formation and maintenance of bone structure, playing additionally a number of functions in the body. According to UNDERWOOD & SUTTLE (1999), phosphorus is found in a high concentration in bone tissue where together with calcium they form hydroxyapatite, which is the major constituent of the skeleton. Phosphorus portion not related to the structural function in the body is contained in high-value organic molecules,...
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Lesaffre has completed the acquisition of dsm-firmenich’s yeast extract business
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Introduction Porcine Epidemic Diarrhea Virus (PEDV) is an enveloped single-stranded positive-sense RNA virus that was first identified in the United States in May 2013. Epidemiological and controlled experiments have shown that complete feed or feed components can be one of many possible vectors of transmission of PEDV. 1 Previous research has shown that a 2% and 1% mixture of caproic, caprylic, and capric acids can reduce the risk of PEDV in a complete swine diet....
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