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In this video, Dr. Ryan Ordway from Balchem explores how Niashure, a natural, non-medicated nutritional solution is designed to support animals through the critical transition period. ...
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Introduction Animal production faces serious challenges, having to feed a growing population while dealing with increased competition for land, climate change and having to take a more sustainable approach. Sustainable agriculture requires us to meet society’s present needs without compromising the ability for current, or future generations, to meet their needs. The effectiveness by which an animal is capable to transform feed biomass into animal products determines the amount...
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May 7, 2025
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Introduction Trace minerals exist in cells and tissues of the body in a variety of chemical combinations and characteristic concentrations, depending on the trace mineral consumed and the tissue in which the trace mineral is metabolized (McDowell, 1992; Underwood and Suttle, 1999). Concentrations of trace minerals must be maintained within narrow limits in a cell (McDowell, 1989, 1992; Underwood and Suttle, 1999). Trace mineral deficiencies, toxicities, and imbalances require the...
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Introduction The dairy industry continues to provide a nutritious food source to our growing global population. Throughout history this industry has undergone significant evolutions contributing to a “more sustainable” product. But what does sustainability really mean, and in animal agriculture, why do we care? According to the U.S. National Environmental Policy Act (NEPA) of 1969 sustainability is to “create and maintain conditions, under which humans and nature...
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José Manuel Oropeza Meza
MSD - Merck Animal Health
Gerente Nacional Cuentas Clave en MSD Salud Animal
United States
United States
Introduction The global agricultural sector, including associated land-use changes, was responsible for emitting 10.6 gigatons (Gt) of carbon dioxide equivalent (CO 2 e), contributing considerably to the overall 53 Gt CO 2 e of global greenhouse gas (GHG) emissions (FAO, 2023). In the United States, the agriculture sector contributed 0.59 Gt CO 2 e in 2022, representing 9.36% of the nation's GHG emissions. This marked a 7.7% increase from 1990 levels...
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The discovery of choline dates back to 1850s when French pharmacist, Théodore Gobley discovered a group of phospholipids that he named lecithin. Seventy years later, during the discovery of insulin by Frederick Banting, his student Charles Best noticed that depancreatized dogs developed hepatic lipidosis. Subsequently in the early 1930s, Best showed that supplementing lecithin reversed and prevented hepatic lipidosis in dogs and rats. It took another 67 years for dietary choline to be...
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Supplementation with rumen-protected methionine optimized Lys/Met ratio in dairy rations based on alfalfa and corn silage
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It is not surprising to me that the success of dairy production in harsh environmental conditions in Israel. This review indicates that the Israeli cow became the “world champion” in milk production. The production of milk with economic efficiency and a relatively low emission of methane into the environment. It seems to me that not only the genetic factor of Israel cattle breed but other factors e,g, environmental management, nutrition, animal husbandry, physiiological and biochemical...
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Choline supplementation is known to modify hepatic lipid metabolism in the dairy cow, but little is known about its effect on mammary lipid metabolism. The objective of this study was to characterize the effect of increasing doses of abomasally infused choline on milk production and milk lipids using untargeted lipomics. A total of 12 ruminally cannulated Holstein cows were used in a 4 × 4 Latin square design with 7-d experimental and 7-d rest periods. All cows were fed a common TMR...
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In this conversation with Dr. Ryan Ordway from Balchem, we dive into how dairy farmers can manage the transition period without relying on Kextone. The key? Preventing ketosis through proper nutrition and management. ...
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Evonik recently hosted THE SCIENCING EVENT, bringing together more than 100 valued customers and industry experts during the highly anticipated VIV Asia 2025 in Bangkok, Thailand. The event served as a dynamic platform for sharing cutting-edge scientific insights and exploring the latest innovations that are shaping the industry.
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Heat stress (HS) has detrimental effects during all stages of dairy cattle life. Cows that experience HS reduce dry matter intake, milk yield, and its composition. In addition, HS has major effects on a cow's health and fertility and negatively impacts a cow's welfare. The decrease in the efficiency of milk production in such conditions increases the negative contribution of the world dairy sector to the environment and brings large economic losses to dairy farmers and the entire...
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Current approaches to study choline bioavailability do not account for the ruminal or postruminal bacterial degradation of choline to trimethylamine (TMA) and TMA N-oxide (TMAO). To evaluate choline bioavailability, 8 multiparous Holstein cows (184 ± 109 d in milk) were enrolled in a study with a 4 × 4 Latin square design. Treatments were (1) 0 g/d of supplemental choline chloride (CTR), (2) 16.8 g/d of unprotected choline chloride (CC) delivered as a continuous ruminal infusion...
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Supplementation with rumen-protected methionine optimized Lys/Met ratio in dairy rations based on alfalfa and corn silage
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1. Introduction Lactoperoxidase is one of the main protein enzymes in milk, and is found in average concentrations of 30 mg/L, much higher than the biological requirements for an optimal enzymatic reaction [1]. This enzyme belongs to the group of oxidoreductases, and is responsible for the bactericidal and bacteriostatic phase during the first hours after milking [2-4]. Lactoperoxidase enzyme is a milk protein with special biological activities, and particularly those that are...
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Multiple EAA drive milk protein production in dairy cows, including His, Ile, Leu, Lys, Met, and Thr. Therefore, determining bioavailability of rumen-protected AA (RPAA) is essential for optimal EAA supply. We aimed to evaluate bioavailability of lipid-encapsulated prototypes of His, Ile, Lys, Met, and Thr and an isopropyl ester of 2-hydroxy-4- (methylthio) butanoic acid (HMBi). Six Holstein heifers (518 ± 28 kg BW) were allocated in a 6 × 8 Youden square design, with 8 periods...
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Dry period heat stress significantly reduces milk yield in the subsequent lactation in cows. Altered methylation patterns in mammary tissues is associated with the decline in milk yield. We hypothesized that as a methyl donor, choline (RPC) supplementation reverses similar patterns of methylation and thus productivity in heat-stressed dams. Late-gestation Holstein cows (n = 51) housed in freestall barns were enrolled to either heat stress (HT, n = 12), HT with RPC (HTC, n = 11), cooling (CL,...
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The negative effects of heat stress and ways to deal with them are currently among the most important research areas. The reason for this is clear, heat stress has become the greatest cause of economic losses to dairy herds, including in regions with a relatively temperate climate, which have only begun to feel the problem in recent years. Evidence of the importance of the issue can be found in the following figure, taken from a recently published article and reviewing the sharp...
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I decided to write this article following a concrete case, in which I was asked to give an opinion regarding the purchase of fans to cool the cows along the feed line of a certain dairy farm. This manager was 240 meters long and was used to feed (and cool) 320 cows. The dairy owner had two proposals for fans to be installed in the feeding area. The first fan was 50″ in diameter with a 1.5 hp motor and belt drive, with a power consumption of 1.1 kWh. In order to achieve the...
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Amino acids (AA) undergo complex metabolism for protein synthesis or excretion after oxidation. We investigated the fate of metabolizable Lys via continuous abomasal infusion of 15 N-Lys. Four rumen-cannulated Holstein cows (147.0 ± 63.2 d in milk, 49.4 ± 9.5 kg milk yield) received 0.6 g/d of 15 N-Lys into the abomasum for 5 d. Cows were offered a common diet (16.6% crude protein; 89% of metabolizable Lys requirement) once daily for an ad libitum intake....
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Supplementation with rumen-protected methionine optimized Lys/Met ratio in dairy rations based on alfalfa and corn silage
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Choline is a methyl donor, which may influence DNA methylation, gene expression, and cellular processes. Past studies have found an increase in milk yield when periparturient dairy cows were supplemented with dietary rumen-protected choline (RPC); however, the mechanism behind this response is unknown. Therefore, the objective of this study was to assess the effects of dietary RPC supplementation on mammary epigenome-wide DNA methylation. Parous Holstein cows were blocked by calving month...
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Lecture given as part of bpt (German National Veterinarians Association) meeting 2024, held as part Euro Tier exhibition, Hannover, Germany. The principal factors affecting world dairy sectors in summer are climate change (global warming) and the Increase cow’s productivity. The high yielding cow generates more than 2000 W of heat (like 25 persons), which is much above her capability to dissipate, in a typical summer day. The cow in Germany will...
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