Introduction Infectious bronchitis (IB) virus, first described in the 1930s (Schalk & Hawn, 1931), continues to be a major cause of disease in chickens of all ages and types in all parts of the world (Anon, 1988, 1991). Good quality vaccines have been available to control IB infections since the 1950s. However, despite their careful use, IB continues to be a major problem. One reason for t...
Dear Sawsan ,
First thank you for your message . It has mentioned on my article, IB 4/91 , QX , Vart 2 , selumaneh , Iranian strains .
All the best
Bakri
Dear Dr, Bakri
Thanks for your efforts. I would like to know about circulating IBV virus in UAE and If there were any proved results about presence of IS/1494/06 in UAE.
Thanks in advance.
M. Houta
Dear Brother Husam,
A very happy new year to you & all staff of MSD. I am agree with your suggestions to overcome the losses of IB Variants in Middle East.
Based on my long experience of working in Middle East and several knowledgeable discussion with you on this issue, I have applied the similar control measures in Karachi area of Pakistan.
For your kind information, many IB Variant unvaccinated commercial layer flocks without any drop in feed, apparently showing field exposure of unidentified IBV (Variant strains), resulted severe drop in egg production with deterioration of egg shell & egg albumen quality. P.M. examination showed lesions of FALSE LAYERS.
Single dose of live vaccine of IB (Ma-5 + 4/91) was given via drinking water route and almost one week post vaccination a remarkable increase in egg production & improvement in egg quality was noticed.
Best regards
Dr. M.Akram
Dr. Mohammad Akram Dear Dr Akram, As you mention, I would like to know that when did you apply ( Ma5+ 4/91)? At DO or when you saw clinical of false layer? Thanks
Dear Dr.Nguyen nhu nguyen,
Vaccine was applied during egg production at different age in different farms, based on the observation of signs & lesions of IB infection as mentioned in my comments. Regards
Nguyen nhu nguyen : To get good protraction against IB infection from variants strains like QX you must give the vaccines at day one Mass+variants to avoid false layer during production. As soon I see this problem this means flock got the infection first 2 weeks
Kamalmousa Ghedan, thank you for your question. As we have several IB variants challenging layer & breeder, using several IB variants strains before production will be great to protect birds and to be primier for killed vaccine and QX vaccine to be one from them will be good. Also, I advice to use the IB killed with different IB variants on it will give good antibodies, as more antibodies mean more protection during production.
Husam Bakri , if we use both IB classical and variant at one day old, we see alot of reaction. Why don't we move keep IB classical at day 1 and move variant to day 7 or 10? I saw alot CRD and another respiratory diseases of we do variant at day 1.
First, thank you for your comments. The standard vaccination day for variants strains 14 days and the class one one day old. Using variants strain day one just when you are fasing IB probable at early age. To get good results from live respiratory vaccine make the interval between them at least 12 days.
Respected Dr Hisham greetings
Deeply sorry for that mistake I mean weak immunity that is to say the mean titre of IB is spare in amount Compare to that of ND
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K.Balasubramanian
17 de enero de 2019
Sir, Good evening, How to identify the field strain and vaccine strain in modern lab.
K.Balasubramanian First, thank you for your question and sorry for the late reply as I was traveling. Usually, we do PCR after we do sequencing here the most important to know is the vaccine strain sequence.
The challenges I am getting, which may be similar to the above complaints, is that immunity is short lived and sometimes not there at all because many attacks have come in after several vaccinations have been done, and to make it worse these bacterial molecules become resistant to antibiotics very fast.
Dr Prafull Zade, vaccine only for healthy birds, no vaccine company recommend for diseases birds. But in practice, we must know how many percent of the flock gets infection and the rest of the farm also. IB live vaccine will help if we do when the morbility still low and we want to protect the rest of farm. And if we do when the morbility too high, the farm will get more inflection. And it depends on what kind of IB vaccine you use, classical will respond immunity faster than variant.
You did all your vaccines correctly. But found a viral disease. There is no known medicament. Reason not known. maybe vaccine did not work. maybe the flock got it before the immunity is established? Any spray will further distress the respiratory system. Any attempt to inject will spread the problem through the needle. The spread is slow and worrying daily with deaths and drop in production. So what is left in doctor's hand. you spread it fast and it will end soon. Better you use an attenuated spread (vaccine) rather than the disease virus spreading slowly in vaccinated birds.
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K.Balasubramanian
8 de septiembre de 2019
Dr. thank you and great work. I want to know how to identify the IB variant strain in PCR. Please inform and give the primer design and cycle conditions.
K.Balasubramanian First, I would like to apologize for the delay in replying. Usually we do general PCR It is positive we do PCR for variants strains which available in the market now. Sorry again for the late reply.
Can hussam bakri help us to identify new strains of IB.
we have issues like sudden production drops suggestive of IB symptomatically inspire of using killed IB , MA5 AND 4/91. what ever samples required can be sent where ever advised.
No mortality. no respiratory symptoms. production drops while reaching peak from 80% to 40%. Fertility also drops. confirmed not A.E. brown layer flocks 26 weeks age.
Husam Bakri (To get good results from live respiratory vaccine make the interval between them at least 12 days.) please do you have mre explanation for that point? Thanks
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