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Swine gut health

Pigs are exposed to various challenges such as weaning, environmental stressors, unhealthy diet, diseases and infections during their lifetime which adversely affects the gut microbiome. The inability of the pig microbiome to return to the pre-challenge baseline may lead to dysbiosis resulting in the outbreak of diseases. Therefore, the maintenance of gut microbiome diversity, robustness and stability has been influential for optimum intestinal health after perturbations. Nowadays human and animal researches have focused on more holistic approaches to obtain a robust gut microbiota that provides protection against pathogens and improves the digestive physiology and the immune system. The swine gut microbiome is a complex and dynamic ecosystem harboring immensely diverse microbiota including bacteria, viruses, archaea, and fungi that ideally reside symbiotically in the gut of host animals. Among the microorganisms, the number of bacteria outnumbers other microorganisms. The microbiome robustness, the maintenance of diverse and functional microbiota in GIT is crucial for effective swine production. The microbiome robustness depends on the diversity of the microbiome, so it is not enough just to have the presence of a few different beneficial microbes. Accordingly, new strategies are required to manipulate the gut microbiome to prevent or revert unhealthy states caused by perturbations.
Phileo’s first global virtual event giving easy access to top talks on microbiota Marquette, France (May 23, 2022) – It’s with great pleasure that we announce the upcoming Phileo Microbiota Days June, 14–15, 2022. This virtual...
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Non-starch polysaccharides are polymeric carbohydrates that are different from starch. NSP cannot be digested by the animals because they are cross-linked (a cross-link is a bond that links one polymer chain to another)....
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Prof. Jürgen Zentek
Institut für Tierernährung und Stoffwechselphysiologie
How important is the pig’s microbiome? The intestinal  microbiota  plays a major role in the development of the immune system, the stability of the digestive process and intestinal health. All of these are prerequisites for the overall performance and animal health. The microbiome should therefore be nurtured.  The  microbiome is a highly dynamic process and changes drastically in its composition from the day the piglet is born. Right...
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Pedro Urriola
Pedro Urriola and 3 more
University of Minnesota
University of Minnesota
INTRODUCTION One of the greatest challenges in optimizing growth performance and health of newly weaned pigs is to overcome low and variable feed consumption which adversely affects gastrointestinal health during this critical transition period on commercial swine farms (Pluske et al., 1997; Langendijk et al. 2007; Dong and Pluske, 2007). Therefore, dietary interventions that encourage faster adaptation and greater feed consumption, while also improving energy and...
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Todd Callaway
Todd Callaway and 3 more
University of Georgia
University of Georgia
INTRODUCTION Antibiotics have given significant contributions to the human food production chain during their almost 80 years of use. Such contributions include a reduced incidence of bacterial disease, improved animal health status, and an overall enhancement in production efficiency (1, 2). However, due to concerns of antimicrobial resistance and its consequences to human health, the entire food-producing industry is under pressure to remove antibiotics from animal production...
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Ryan Arsenault
University of Delaware
University of Delaware
Immunometabolism is the study of immunity and metabolism as an integrated system. The prototypical organ for such study is the gut. Central to the proper and optimum functioning of the gut, thus its immunometabolism, is the microbiota. Often the microbiota is considered only in the context of what functions, molecules and signals it provides to the host. However, the interactions between the host and microbiota must fundamentally be understood as bidirectional communication. In the realm of...
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Introduction: Enteric infections cause economic losses in pig production. Increases in costs are associated with reduced average daily gain (ADG), increased mortality rate and increased in use of antibiotics. Porcine proliferative enteropathies (PPE), swine dysentery (SD), porcine spirochetosis and salmonellosis are enteric diseases caused by L. intracellularis (LI), B. hyodysenteriae (BH), B. pilosicoli (BP) and Salmonella enterica ...
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Pedro Rubio Nistal
Universidad de Leon - España
Universidad de Leon - España
Introduction: Brachyspira hyodysenteriae is the aetiologic agent of swine dysentery (SD), an infectious disease that affects growing and fattening pigs causing severe bloody diarrhoea and haemorrhagic colitis. Brachyspira pilosicoli causes a non-fatal and non-bloody milder catarrhal colitis named porcine intestinal spirochaetosis (PIS) in young pigs. Our purpose has been to determine the prevalence of these two spirochaetes in Spanish farms with...
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INTRODUCTION According to new concepts about human health and increase on protein demand there was significant improvement in carcass quality of pigs to supply market which seeks a pork lean meat. Thus, it should be considered some conditions that impose changes in nutritional requirements of pigs, such as genetic potential for meat production, gender and age for maximal performance. Amino acid levels in most of diets are recommended from the data reviewed (National...
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Ermin Magtagnob
ADM Animal Nutrition
Digestive capability of young animals is different when compared to adult growing pigs and chickens. In this TechTalk, Ermin Magtagnob, Novus Technical Services Manager from Southeast Asia and Pacific, discusses how protease enzymes can assist in managing gut health problems associated with undigested proteins....
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Copper is very useful for young animals’ gut health, particularly for the integrity of the small intestine. In this final Young Animal TechTalk, Matthew Bekker, Technical Services Manager for Novus Southeast Asia and Pacific, shares how copper in chelated form is highly valuable to chick’s and piglet’s epithelial cells and villous structure....
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Early nutrition and feeding play a very important role to modulate the immature immune system of chicks and piglets. In this TechTalk, Teera Tiyasatkulkovit, Technical Services Manager for Novus Southeast Asia and Pacific, talks about how essential oils can complement the animal’s innate immune system and enhance their adaptive immune system to protect young animals and support their growth....
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David Knudsen
South Dakota State University
South Dakota State University
Introduction: Mesocolon edema syndrome is recognized as a common cause of diarrhea in pigs less than 2 weeks of age, and has been associated with neonatal colonization by Clostridium difficile , C. perfringens , or often as a combined infection. In the United States, C. perfringens type A is increasing in prevalence, but C. difficile colonization and subsequent enterotoxemia is still an important cause of the syndrome. In this study, we directly...
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Introduction Prevention of disease transmission and enhancement of growth and feed efficiency are critical factors in modern pig production. For more than 50 years enteric disease suppression and growth promotion have been effectively achieved by the inclusion of various antibiotics or chemotherapeutics at subtherapeutic doses into diets. The estimated economic benefits in terms of improved growth rates ranged from 3.3 to 8.8% and feed efficiency from 2.5 to 7.0% (Viaene...
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Bruno Maria Goddeeris
Katholieke Universiteit Leuven
Katholieke Universiteit Leuven
Introduction For economic reasons, the pig industry is marked today by a phenotypic inbreeding for production parameters that might result in a genotypic linkage with an altered (compromised) immune responsiveness. A well-developed immune system and optimal immune responsiveness remain important for the welfare and productivity. Indeed these qualities can only be obtained if the health status of the animal scores high. Therefore a lot of energy and money is invested in...
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Introduction Colibacillosis is generally defined the infection with Escherichia coli characterized by many clinical forms. E. coli is a gram negative peritrichously flagellated bacteria belonging to the family Enterobatteriaceae and is the causative agent of a wide range of diseases in pigs, including neonatal diarrhoea, post-weaning diarrhoea (PWD), oedema disease (ED), septicaemia, polyserositis, coliform mastitis (CM) and urinary tract infection (UTI) (Fairbrother and Gyles,...
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John O Doherty
John O Doherty and 2 more
Improving feed efficiency (FE) reduces the environmental impact and increases the profitability of pig production. Despite the improvements in pig FE achieved in recent years 1,2 , it still takes~3.5 kg of feed to produce 1 kg of saleable pig meat 2–4 . Nutritional strategies can be implemented to improve FE; however, the impact of these strategies on the microbial composition of the gastrointestinal tract (GIT) is seldom explored. This is surprising given...
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Peter Ramaekers
Trouw Nutrition
ABSTRACT The objective of this study is to investigate the effect of a maternal antibiotic administration during the last week of gestation on the early life intestinal development in neonatal piglets. Colonization of the gut with bacteria starts during birth and plays a major role in the intestinal and immunological development of the intestine. We demonstrate that maternal interventions induced changes in the sows (n = 6 to 8 per treatment) fecal microbiota diversity...
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