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Swine gut health

Pigs are exposed to various challenges such as weaning, environmental stressors, unhealthy diet, diseases and infections during their lifetime which adversely affects the gut microbiome. The inability of the pig microbiome to return to the pre-challenge baseline may lead to dysbiosis resulting in the outbreak of diseases. Therefore, the maintenance of gut microbiome diversity, robustness and stability has been influential for optimum intestinal health after perturbations. Nowadays human and animal researches have focused on more holistic approaches to obtain a robust gut microbiota that provides protection against pathogens and improves the digestive physiology and the immune system. The swine gut microbiome is a complex and dynamic ecosystem harboring immensely diverse microbiota including bacteria, viruses, archaea, and fungi that ideally reside symbiotically in the gut of host animals. Among the microorganisms, the number of bacteria outnumbers other microorganisms. The microbiome robustness, the maintenance of diverse and functional microbiota in GIT is crucial for effective swine production. The microbiome robustness depends on the diversity of the microbiome, so it is not enough just to have the presence of a few different beneficial microbes. Accordingly, new strategies are required to manipulate the gut microbiome to prevent or revert unhealthy states caused by perturbations.
David Val-Laillet
Institut National de la Recherche Agronomique (INRA)
Institut National de la Recherche Agronomique (INRA)
Introduction Numerous reviews have been written to describe the specificities and advantages of the pig model in studies focusing on behavior, nutrition and neuroscience (Kornum and Knudsen, 2011, Roura et al., 2016, Val-Laillet, 2019). Besides the fact that the pig is an animal species of obvious interest in agriculture and human food production, it also has incomparable advantages when it comes to studying the consequences of the nutritional environments, diets or feed in...
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There are several components of grain and plants that can cause detrimental effects on animal production. These components are commonly known as antinutritional factors. According to their mode of action, anti-nutritional factors can be grouped as follows: Substances that limit or decrease the digestion or metabolism of proteins, ex. lectins and saponins. Substances that interfere or decrease the correct utilization of minerals, ex. phytic acid and oxalic...
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We have a small farm in Pa. USA and have had several instances in young pigs were the intestines have protruded from the rectum. What are the most likely causes and is there any thing that can be done to fix the problem once it happens short of slaughter? ...
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New component in the Gut Health Solutions portfolio from Evonik Animal Nutrition Phytogenics are important components of alternative solutions to antibiotic growth promoters Product from this partnership to be available in Europe in the first quarter of 2023 Essen, Germany. Evonik and Dr. Eckel Animal Nutrition have entered into a partnership effective January 1, 2023. This agreement will enable Evonik's Animal Nutrition business line to expand its...
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Peter Surai
Scottish Agricultural College - SAC
Scottish Agricultural College - SAC
For many years reactive oxygen species (ROS) production in biological systems has been considered to be detrimental. However, a pleasant face of ROS has received recently tremendous attention. Indeed, it has been proven that ROS participate in cell signalling, transcription factors regulation and vitagene activation to maintain optimal cellular redox balance and to provide an effective stress adaptation [1]. In fact, redox biology is a very rapidly developing area of modern biological...
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Dr. Henri Salmon
French National Institute for Agricultural Research (INRA)
French National Institute for Agricultural Research (INRA)
Introduction The infection by enterotoxigenic Escherichia coli (ETEC) is one on the most important causes of neonatal and postweaning diarrhea (PWD) in piglets. ETEC causes significant morbidity and mortality, resulting in a large economic loses in the porcine industry. One of the most common ETEC in swine is serotype 0149 which carries the K88 (F4) adhesin that enables the attachment of the bacteria to the intestinal epithelium. ETEC colonizes ileum [1,2], penetrate the...
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Andrea Piva
Andrea Piva and 3 more
Vetagro S.p.A.
Botanicals represent a wide class of complex compounds that naturally contain active principles with numerous biological functions. Among them, the anti-inflammatory and antioxidant actions are of key interest to support intestinal health during stressful phases. The aim of this study was to investigate the ability of a thymol-based blend of botanicals (BOT) to protect intestinal Caco-2 cells from the damages induced by an inflammatory challenge in vitro. Caco-2 cells were differentiated on...
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Bill Shannon (BioRankings) talks about microbiome, untargeted metabolomics, and other data that have high potential for changing how biomarker discovery research is done, during the Symposium on Gut Health in St. Louis, USA....
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Federico Ghiselli
Bologna University
Bologna University
Federico Ghiselli (University of Bologna) speaks on the test results of a feed additive and its impact on inflammation and epithelial integrity, during the Symposium on Gut Health in St. Louis, USA....
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Andrea Bonetti
Bologna University
Bologna University
Andrea Bonetti (University of Bologna) talks about this nutritional supplement and its effect on intestinal integrity, during the Symposium on Gut Health in St. Louis, USA....
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