Participation in Forum on September 17, 2019
Yes, by using carnitine as a part of antioxidant strategy it is possible to improve antioxidant defences piglets in early postnatal development
Participation in Forum on September 17, 2019
Yes, carnitine can have some protective effects in vitro
Participation in Forum on September 17, 2019
Dear Juarez, carnitine can improve mitochondria integrity in stress conditions, including heat stress. Since mitochondria are the main source of free radicals in the cell, carnitine can decrease oxidative stress. Furthermore, carnitine can also affect Nrf2 activity and by doing so further increase antioxidant defences
Article published the August 3, 2017
Introduction L-carnitine (LC) is a naturally occurring and widely distributed in nature compound. It was discovered in 1905 in Liebig’s meat extracts, a popular ‘dietary supplement’ at that time, by Gulewitsch and Krimberg [1] who named the substance from the Latin word for flesh (“carnus”). Carnitine chemical structure was established in 1927 and its function was re ...
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Participation in Forum on July 17, 2017
Thank you for comments, I would like to stress the following: 1. Organic minerals will not solve the problem of the stress, their supplementation is effective only in the case of dietary mineral (Zn, Mn, Cu, Se) deficiency. If the diet is adequate in these minerals, there would not be much response in terms of antioxidant enzyme synthesis. The technology of supplying special vitagene-regulating m ...
Article published the June 22, 2017
1. Introduction Breeding programmes are designed to produce a broiler with high potential for growth, yield, and feed efficiency. These traits may compromise health status under husbandry designed to maximise this genetic potential, since there is a trade-off between growth- and health-related traits with responses to husbandry programmes, age, sex, and genetic line (Siegel et al., 2001). In thi ...
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Article published the May 11, 2017
INTRODUCTION Boar spermatozoa are characterized by high susceptibility to lipid peroxidation (Cerolini et al., 2000). Indeed, mammalian spermatozoa are unique in structure and chemical composition and contain high proportions of polyunsaturated fatty acids (PUFAs) in the phospholipid fraction of their membranes (Cerolini et al., 2000; Surai, 2002; 2006). This feature of these highly specialized c ...
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Participation in Forum on March 23, 2017
Yes, indeed, carnitine could be a part of the antioxidant mixture to deal with various stresses.
Article published the March 22, 2017
Abbreviations ALC: Acetyl-L-Carnitine; AREs: Antioxidant Response Elements; BSA: Bovine Serum Albumin; b.w.: Body Weight; CoQ: Coenzyme Q; eNOS: Endothelial Nitric Oxide Synthase; FFA: Free Fatty Acids; γGCS: γ-Glutamate Cysteine Ligase; GRα: Glucocorticoid Receptor-α; GR: Glutathione Reductase; GSH: Glutathione; GSHPx: Glutathione Peroxidase; GST: Glutathione Transferase; ...
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Article published the March 13, 2017
Introduction L-carnitine (LC), a naturally occurring and widely distributed in nature compound was discovered in 1905 by Gulewitsch and Krimberg [1]. For the last 50 years this nutrient has received a substantial attention from medical sciences and poultry and pig nutritionists. Main dietary sources of carnitine in poultry/animal nutrition are animal-derived feed ingredients while grains and thei ...
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