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Bacillus subtilis 29784 improved the growth performance of broilers

Published: December 11, 2019
"A probiotic strain is capable of inducing beneficial effects on growth performance and could be a reliable alternative to AGP", said Damien Prévéraud, Global Scientific Support at Adisseo, during his presentation in the 8th Symposium on Gut Health in Production of Food Animals in St. Louis, USA.
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Authors:
Damien P. Prévéraud
Adisseo
Influencers who recommended :
Dr. Fiodor S. Marchenkov
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Michael McGrew
Roslin Institute
Roslin Institute
5 de marzo de 2020
I would like to know what cells were used for the TEER assay? Were these chicken cells or Caco-2 cells?
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Juarez Donzele
Universidade Federal de Viçosa - UFV
Universidade Federal de Viçosa - UFV
3 de marzo de 2020

Based on your knowledge on the subject, Dr. Damien, I would like to know if the bacillus strain used produces the BSH enzyme, which is common in some strains of lactobacilli and bifidobacteria also used as probiotics. This is because this enzyme by hydrolyzing bile salts can harm birds in which the oil is used in the food. And I would also like to know if there is a possibility that this strain transfers antibiotic resistance to pathogenic microorganisms.

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Haroon Mushtaq
21 de febrero de 2020

Damien Preveraud, thank you for your response. Can you please elaborate a bit on thermostability of this probiotic? Will it withstand ~90C that’s usually observed in our country during Summer time? If yes, then what’s the technology behind?

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Alemu Regassa
University of Manitoba
University of Manitoba
21 de febrero de 2020
How could you reach on this conclusion? What was the birds fed? A probiotic containing Bacillus subtilis only? Or was Bacillus subtilis the only strain identified in fecal or digesta material?
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Damien P. Prévéraud
Adisseo
6 de enero de 2020

Thanks all for your comments. In these data presented in St Louis, we clearly demonstrated that bacillus Subtilis 29784 improved performance (standard and challenged conditions) thanks to their metabolites able to control overall inflammation (activation of NfkB pathway) and to improve gut integrity (expression of tight junction). This could also occur indirectly through the shift of microbiota of beneficial bacteria.

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reynaldo azupardo
3 de marzo de 2020
Would Bacillus subtilis 29784 develop spores outside of d bird's bodies? or how are the spores develop?
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Ankur Gupta
Arevin
28 de febrero de 2020
Dear Haroon, Hi I am working with a company with similar strains of Probiotics and Let us try to answer your question in this way: A). The vegetative form of Bacillus bacteria grows with a temperature optimum between 30 and 40 °C but spores are mostly resistant to 95-100 C. B). Spores that form in Bacillus type bacteria provide dormancy at high temperature because enzyme proteins change shape as the spore dehydrates. These tough capsules form in response to adverse conditions such as drought or high temperatures.
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Amin Nahal
29 de diciembre de 2019

bacillus subtilis 29784 improved the growth only not anti clostridia

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Muhammad Farooq
20 de diciembre de 2019

The single stomach animals have very much less bacterial activity for contribution towards FCR. but Probiotics may enhance the digestibility of nutrients and contribution towards gut health by increasing the acidic medium provided prebiotic also there.

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