Discussion created on 01/19/2017

How matrix value of enzymes calculated?

Who has any idea about how matrix value of enzymes is calculated? What is this matrix value? How is it important in relation to animal feeds?

Anonymous query
Kenya
BSc. Animal Science
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January 20, 2017
Dear Sir,

We are feed mill producer so we do not have information about receipts
Regards
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Dr Piotr Stanislawski Dr Piotr Stanislawski
Nutritionist
DSM DSM
January 20, 2017
Hello Anonymous,
I'll try to explain it. Matrix is prepared based on several trials.For enzymes used for more years there are really many trials (sometimes the matrix is corrected/updated).Comparison of the results of feed with (few levels) and without (control) the enzymes give the researcher the answer "how the enzyme influence/uplift exact nutrients values:eg. ME, avP,Ca,AA...).Then the matrix is created (I mean just the serious company/producer).
For eg.phytase we use uplift of macrominerals as Ca, avP, digP, Na, aminoacids, CP ,ME (in case of NSP enzymes addition the value in matrix must be lowered).The values are different for age,species,dose.
Matrix describes the values for 1 kg product.Then acc.to used dose (eg.100g product/t feed) proper part of the value is used in formulation program (LCF).
In such way the feed "receive" additional values for some cost creating nutrients (on paper). Later enzymes included in feed, start the activity working in physiological conditions (proper pH,temperature) and some more value from the substrate is obtain. The savings are in the feed mill and on a farm; eg. the dose of phytase replace 6-7 kg MCP and overdose results on a farm with better performance.
But...To get positive response of any enzyme and savings it should be done and decided by nutritionist based on the feed composition and RM prices.
Hope it gives you an idea how the matrix is created and used.
rgds Piotr
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Steffen Hansen Steffen Hansen
Animal Nutritionist
January 20, 2017
Matrix values describes the amount of additional nutrients that are released when you add the enzyme. If you study the matrix values for a phytase product you will notice that the manufacturer claims that his product releases xx g of dig. P per kg. feed or is equivalent to adding xx g of DCP/MCP to the feed. If you are studying the matrix values for carbohydrases you will typically notice that the manufacturer believes that the enzyme releases a given amount of energy and very often also has an effect on available amino acids.
Ideally the enzyme manufacturers derive the matrix values from several digestibility trials. However, ask the provider of the enzyme to provide documentation on how they have obtained the matrix values. It is easy to present great matrix values, but if these values are based on a very limited number of trials you can end up formulating your feed with a skewed energy:nutrient relationship.
If the company claims that his or her product is identical to the product from one of the renowned producers in terms of matrix values, you risk to waste your money. Do also pay attention to the fact that the enzyme you add to the feed only works if the corresponding substrate is present.
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mozhdeh mozhdeh
Student
September 19, 2017
How matrix value of enzymes calculated??
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March 11, 2019

Thank you so much, Professor, for giving valuable information.

Professor, till now I feel confused in this regard because I couldn't find calculate method.

Could you help me how can calculate it exactly? As for example the effect of phytase on broilers.

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August 27, 2021
Matrix value actually represents the nutrients available in feed additive.
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Steffen Hansen Steffen Hansen
Animal Nutritionist
September 2, 2021
That is not true. Matrix values express the amount of nutrients the manufacturer of an enzyme product believes the product can release. All enzymes are substrate specific, so the matrix value will be wrong if you add an enzyme in a diet with no substrate for that enzyme.
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Talaat Mostafa  El-Sheikh Talaat Mostafa El-Sheikh
T. M. El-Sheikh Prof. Dr. of Poultry Production, Head of Animal & Poultry Prod. Dept.
September 4, 2021

This expression is new for me. We need more explain.
Is there a formula to calculate it? or is it within feed formulation program?

Reply
Steffen Hansen Steffen Hansen
Animal Nutritionist
September 5, 2021
Talaat Mostafa El-Sheikh, the manufacturers of the enzyme products, conduct trials to estimate the amount of nutrients the specific enzyme releases, such as energy, phosphorus, amino acids, etc. The matrix values express the difference between Control and the Control + enzyme. It is important to ask the distributor/manufacturer of the given enzyme product how many trials they used to derive the matrix values. If only one or two trials comprising few animals are the foundation for the matrix values, these are not very reliable. Suppose the matrix values are merely a copy of renowned products. In that case, it is recommended to avoid that product because every enzyme has a different effect due to different pH optima, kinetics, temperature profiles etc.
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Talaat Mostafa  El-Sheikh Talaat Mostafa El-Sheikh
T. M. El-Sheikh Prof. Dr. of Poultry Production, Head of Animal & Poultry Prod. Dept.
September 5, 2021

It is very complicated, so you should calculate the requirement of all nutrients when you want to add an enzyme.

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Martin Smith Martin Smith
Animal Nutritionist
Evonik Animal Nutrition Evonik Animal Nutrition
Rellinghauser, Hessen, Germany
September 6, 2021
Interesting discussion. As Dr. Hansen has explained, enzymes increase the ability of an animal to utilise certain nutrients (energy, phosphorous, amino acid). They do this by helping break down compounds that prevent utilisation; in the case of phytase, this is the phytate complex, in the case of NSP enzmyes, the various non-starch polysaccharides that can prevent adequate digestion of feed components. When formulating I advise to allocate a value for the TOTAL amount of a nutrient; and then a digestibilty factor; in the matrix values. These are then multiplied together to give a digestible nutrient, and THIS is what is used in the feed specification. This then allows for the fact that (Eg) phytase actually contains NO phosphorus; it simply assist the animal extracting phosphorous from feed ingredients. So we set the total P at a very low level, with a very high (eg 1000%!) digestibilty factor.
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