Bacterial chondronecrosis with osteomyelitis in broiler chickens

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Cotter PF. Cytogenetics of Reactive Bone Marrow Associated with a Fungal Infection (Hemomycetes avium) of Ducklings. World J Vet Sci. 2022; 4(1): 1018

Cotter, P. F. 2023. Bone marrow and blood pictures of broilers with BCO
J Anim Res Vet Sci 2023, 7: 048 DOI: 10.24966/ARVS-3751/100048 [Published as a galley proof]

Cotter, P. F. 2015. Hemomycetes avium, a blood-borne fungus of three poultry species. Abs 293.Poultry Science Vol. 94 (E-suppl. 1) 101. Poultry Science Association Annual Meeting Abstracts, July 27-30, 2015 New Orleans, LA

Which bacteria did you isolate in your studies?

Only in 2025, more than 40 studies relating to the broiler gut-bone axis have been published in Google Scholar.
The gut-bone axis is an emerging concept that describes how the gut, particularly its microbiome, influences bone health through complex interactions involving immunological, metabolic, and endocrine pathways.
The gut microbiota produces metabolites such as short-chain fatty acids (SCFAs), which regulate the activity of bone cells, promote calcium absorption, and modulate inflammation, collectively favoring bone formation and reducing bone loss.
Dysbiosis of the gut microbiota can trigger inflammatory responses that lead to increased bone resorption and the onset of conditions such as osteoporosis.
Therapeutic approaches targeting the gut-bone axis include multi-strain probiotics, which have shown potential in improving bone mineral density, preventing bone diseases, and reducing fractures.
This axis is considered a promising target for multidisciplinary treatments aimed at promoting bone health and managing osteoporotic conditions.