Forum: The gut microflora and probiotics can impact stress and behavior

Published on: 12/13/2008
Source : Lallemand Inc.

International scientists gathered for Institut Rosell-Lallemand Scientific Exchange break new ground on probiotics research and pave the way for new applications More than 40 scientists and experts from different universities and research centers across North America and Europe gathered last month in Quebec City to participate in Institut Rosell-Lallemand's Scientific Exchange. With varying thoug...

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December 13, 2008

Relation between stress and stress ameliorating effects of probiotics has been dealt interestingly in this article. We should encourage poultry farmers to consider probiotic as on of the useful supplement and it should be made affordable for regular usage.

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December 14, 2008

Heat stress in tropics, one of the major problems that affect animals, their nutririon, immunity, reproduction, growth and other production potentials. Of course controlling the enviroment is not the optimum solution, but looking for probiotics as alternative I believe it is another option. Perhaps more research is needed to show the significance about the use of probiotics. If the author has any relevant research in such matter, please send me some.
Thanks in advance and hope to hear from you soon.

Dr. Nuha Hamed Talib Ismail

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Saadat Changezi Saadat Changezi
Doctor of Veterinary Medicine
December 14, 2008

In broiler farming, the very first few days of chicks are very critical. Stress factors like transportation, improper brooding, early use of antibiotics, etc, badly affects chicks performance leading to a weak and unhealthy flock. Therefore, use of probiotics in the early days of chicks is a must to get a best performance from a flock.

Dr.Saadat Ali Changezi

Reply
December 15, 2008

Dear Dr Talib,

Thank you for your comments. Indeed, we have few data abour heat stress in ruminants and the use of probiotic yeast. I can suggest that you see the article already published on engormix on the subject:https://www.engormix.com/e_articles_view.asp?art=618&AREA=GDL
Concerning poultry, we have various positive results with probioitc Bacteria in broiler and layers,in intensive farming in India, Egypt, Italy... I can send you some data directly.
if you wish to have further information or scientific data, please contact me.

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Dinabandhu Joardar Dinabandhu Joardar
Doctor of Veterinary Medicine
Novus International Novus International
Missouri, United States
December 15, 2008

Probiotics are an excellent concept, but still lack consistent results even in controlled conditions. We still have to endeavor to learn how to choose a probiotic that will consistently perform in conditions prevailing, nevertheless probiotics have to be chicken specific strains and be given continuously dosed for from day one of chicken (broiler) life. All strains don't work across the board.

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Youssef Attia Youssef Attia
Animal Nutritionist
January 3, 2009

Probiotics and/or prebiotics may be a useful tools for improve gut health, although constant results are lacking. Many factors can affect the response to probiotics and prebiotics most important in the hygienic condition in the farm, time of application, dosage, type of birds and goal. I think we should look to the synergism between the prebiotics and the probiotics at this time. Perhaps a synergistic effects of both could replace the antibiotics. The role of probiotics/prebiotics as stress relief needs more and further details and intensive research.

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lior ben lior ben
Veterinary Doctor
January 3, 2009

Dear Sir,

We raise Cobb and Ross broiler chicks, without the usage of antibiotics and anticoccidials. These green (not organic, since the feed is not organic) chicks are raised till 40 days of age with no much health problems. We use probiotic as prevention through all cycle and acidifiers with proven antibacterial activity in case we need to treat some intestinal disorder. Of course we have strict biosecurity. I will be more than happy to share info with all of you.
With best regards,

Ben Shimon

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Dr Suraj S Dr Suraj S
Veterinary Doctor
January 4, 2009

The concepts of probiotics known for several centuries before they have now gained significance, with people turning from conventional antibiotics to probiotics. There has been several generations of improved probiotics like the first beeing the lactic acid bacteria, and the bifido bacterium, etc, then came in the fungi and the yeast, now we have the spore forming bacteria, and we have still more to come. But what was best in the current discussion was the re-understanding the cross talk between GUT and the Brain. I too work in this area and am very excited to know the renewed interset in this area. Kindly offer your suggestions in this regard.
With Regards,

Dr. Suraj

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May 19, 2009

We have hnown that the probiotic application at day-old of age is being considered as one of the tools in Salmonella control.
Besides, some of the poultry profrssionals advocate Probiotic treatment to replenish the gutmicroflora, followed by antibiotic treatment. Is any one obtained satisfactory results? Please share your views and experience.

Reply
Philippe Gossart Philippe Gossart
Consultant
May 20, 2009

For my part Probiotic trials are positive at 50% (very good) but also negative at 50%... you see what I mean... It is an old concept with various handicaps (to jump)... inconstance quality product, pH instability, & endogenious germs acceptation... Probiotics are heads or tails... good luck !

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May 31, 2009

We all are looking for the alternates to common antibiotics.Probiotics seems to be quite promising.But we are not able to depend on them as we depend on antibiotics,because we have opposite results in variuos trials.Still probiotics have not gained the universal acceptance.Some work need to be done in field, because alternate to antibiotic is a need.

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June 4, 2009

I tend to agree with Mr. Philippe Gossart on this matter.

Even though probiotics are theoretically beneficial for the animal, there are a lot of factors at play in the field. Most of these factors cannot be controlled by human intervention. One example is the continuous battle between pathogenic and beneficial bacteria within the intestinal microbiota. This delicate and inverse relationship is also known as competitive exclusion (CE), where a increase in the beneficial/saprophytic bacterial population would lead to a decrease in the pathogenic bacterial numbers, and vice versa. In stressful conditions or when there is disease challenge, CE tends to favour the intestinal pathogens, such as E. coli and Salmonella. This is even more pronounced in immuno-compromised animals. That is why such bacteria are called opportunistic pathogens - they are ubiquitous and exist in the intestines in small and harmless numbers, but multiply rapidly in such critical situations to populous numbers that can cause intestinal disease, of which diarrhoea is usually the first clinical sign.

Therefore, it is my personal opinion that for the case of probiotics, sometimes they work, and sometimes they dont...and results are always variable. From my experience, they usually fail especially at times of dire and utmost need, which of course are during times of stress or disease challenge. During such critical periods, I would recommend an additive with more potent antibacterial properties, such as oregano essential oil, where killing efficacy is guaranteed and development of bacterial resistance is not possible. Oregano oil has been shown to improve the numbers of beneficial bacteria within the microbiota, such as Lactobacillus spp, while easily killing pathogens such as Salmonella, E. coli, Campylobacter and Clostridium perfringens. The result is a balanced intestinal microbiota and healthier intestines, where absorption of nutrients from the feed can be maximised.

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July 8, 2009

thank you for these added informations about probiotics
it will be valuable in poultry industry
Best Regards

Reply
July 8, 2009

Yes I also agree that probiotics are much useful for stress management. We have tried our product Spectra-DFM (which provides 5x107 cfu per gram of feed) against AGPs during the month of APR and MAY (Peak summer in India). It has performed better than AGPs and proved even to replace AGPs. It i sdue to the high concentration in the feed and 13 different essential organisms.

Reply
Pat Banjo Pat Banjo
Animal Nutritionist
July 14, 2009

If their is a correlation between stress and gut physiology, altering the the gut microbiota and the immunity level of the bird. Also if their are specific probiotic preparations playing specific role in animal response to stress. Then, in the tropics, the greatest stress to efficient poultry production is heat stress. What is the relationship between heat stress, gut physiology and gut microbiota?Is their any research result(s) on probiotics that will reduce the effect(s) of heat stress on animaal production?

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Dr. Mahadi Hasan Dr. Mahadi Hasan
Consultant
August 2, 2011
Dear Ms. Midi-Pyrenees,
My name is Dr. Mahadi Hasan from Bangladesh. I know about your products from your company website as well as most of the research article and know that you have some good products (probiotics) which have a great demands in our country. This concept is new for us. So I think there is a big opportunity of your products in our market for making business. We would like to make business with your company. Please suggest us how can we take the sole distributorship of your company and start business in the coming future.
Hope our better cooperation make fruitful for us. Waiting for your quick and positive reply.
Thanking you.
Best Regards,
Dr. Mahadi Hasan,
DVM, MPH
(Director)
ALTEXCHEMI Corp. Ltd.
Dhaka , Bangladesh

Reply
Sergio Velez Sergio Velez
Animal Nutritionist
December 20, 2012

Perhaps ruminants due to their highy evolved symbiosis with rumen mciroorganisms may give light on other species. In ruminants the condition called ACIDOSIS clearly offers a particular valuable scenario for gut and microbial interaction examination. What we have learned is that ruminal flora is highly changing and very related to diet and in particular to certain physical -chemical parameters of the rumen such as pH, volatuile fatty acid production (salmonella and E. Coli are naturally very low levels in rumens) mode of feed intake, intake level and others.
Contrary to popular belief the rumen is an open system capable of population succesions and in may cases it is the "invasory" flora the cause of disease.

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Dr. K. M. Ehasanul Islam Dr. K. M. Ehasanul Islam
DVM, MS(Theriogenology)
May 8, 2014
This article is better for vet. practitioner at field level. I also see at field level is fruitful . In Bangladesh i suggest for some farm those products like Levucell SB,Clostat, Protexin etc all are show positive response during heat stress against diarrhoea.In Srilankan market also same result for Clostat & Protexin.
Reply
Arnab Banerjee Arnab Banerjee
Specialist in Animal Nutrition
September 27, 2016
Hello Freinds,

Rationally & scientifically developed Probiotic Cocktails which are administered as Direct Fed Microbial(DFM) has the ability to exhibit direct tangible benefits through Gut Health Managements both in monogastric and ruminant animals. SANZYME (earlier known as Uni-Sankyo) has developed multiple spore forming, aerobic, facultative anaerobic and obligatory anaerobic probiotic strains whose appropriate blends can maintain optimum gut microflora balance and provide complete gut management right from CROP to CAECA (C2C) in poultry. The animal health & nutrition fraternity need to start looking beyond BACILLUS SUBTILIS which is just an aerobe and has its activities limited within the small intestine as it requires oxygen for its proliferation. Interesting spore forming probiotic strains of BACILLUS COAGULANS & BACILLUS LICHENIFORMIS (both facultative anaerobes) and CLOSTRIDIUM BUTYRICUM (obligatory anaerobe which grows in the large intestine) along with SACCHAROMYCES BOULARDII (well known for its toxin binding, immunomodulatory, anti-pathogenic and anti-inflammatory actions in monogastrics) are strong candidates for blending with BACILLUS SUBTILIS for alleviating stress impact and improving performance in poultry birds without any inclusion of AGPs. SANZYME's proprietary MICRO-ENCAPSULATION TECHNOLOGY enhances the heat & pressure stability, acid & bile tolerance of all these spore-forming strains when used in PELLET FEEDS.

Best Regards,

ARNAB BANERJEE
General Manager & BU Head
Sanzyme Ltd., Hyderabad, India
Reply
February 17, 2020
Prebiotics should be taken along with the probiotics, as food or in a capsule form. It is important to note however, that adverse interactions between medications and some supplements are common. For example vitamins and minerals that exceed recommended dietary allowances may be harmful. Some common foods, including nuts, dairy products, fish, and eggs, may trigger allergic reactions, which may require emergency medical care. If you are considering taking dietary supplements or dramatically changing your diet, it is important to first consult with your healthcare provider or nutritionist. For more information on nutrition, including a helpful a rating guide to nutrition sites on the Internet, contact the Tufts University Nutrition Navigator at https://pharmacyrxs.com.
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