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Participation in Forum on May 18, 2020
A couple of quick remarks on this topic. When phytic acid is hydrolysed by phytase and the mucosal phosphatases in the intestine the only two direct products of this are myo-inositol and phosphate. We have measured the appearance of both of these in multiple experiments and this is clear evidence of phytase efficacy and its compatibility with endogenous phosphatases in the intestine. All additiona ...
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Aaron Cowieson likes the comment:
Aaron Cowieson Ha ha! :-) He did at least put in a reference to you.
Participation in Forum on May 11, 2020
Ali Afsar I recognize quite a bit of that text...
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This member gave a presentation on January 27, 2020
At the following event:
IPPE - International Production & Processing Expo 2020
Participation in Forum on November 4, 2019
For sure enzyme responses are non-linear but in the range, we test them in animal nutrition they occasionally appear linear. I think it is crucial to also examine available/reactive substrate concentration when interpreting enzyme response. Systems may be saturated with the substrate in which case enzyme responses may be exaggerated across a wide range of inclusion concentrations, or they may be s ...
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Participation in Forum on October 17, 2019
Park W. Waldroup I think FTU, in a generic sense, is largely meaningless from a biological effect perspective but provides a moderately useful index against which phytases can be traded and registered with the appropriate authorities. From the perspective of the animal though, FTU (which is typically measured with substrate, cation, pH etc conditions of limited practical relevance), is poorly corr ...
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Participation in Forum on October 31, 2018
Hi Meg, all useful comments and I agree with most of your points regarding the characteristics of phytases that promote bioefficacy. However, I don't think the title of this video is reflected in the comments that you have made. I've noticed this with several other Engormix videos also. The title should reflect the content of the video. The title here was - 'The key to using phytase in effecti ...
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Participation in Forum on September 20, 2018
Henk Ghesquiere It is theoretically possible to overdose xylanase but in practice, I think this is unlikely to be a significant issue with most xylanases that are available commercially. Firstly, most commercial xylanases are endo-acting and so do not produce appreciable quantities of free xylose or arabinose (which are known to have a net negative energy value for animals as they are readily abso ...
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Participation in Forum on September 5, 2018
Mike Bedford Interesting stuff. Look forward to seeing the caecal sieve info! One thing I can say with some certainty is that the effect of xylanase (and perhaps NSPases in general) appears to be really highly generic i.e. the mechanisms of benefit, whatever they may be, do not seem to favour some nutrients more than others. If you think back to the analysis we published on ileal amino acid digest ...
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Participation in Forum on August 29, 2018
Interesting. It seems perfectly logical to me that if you change the substrate flow into the caudal gut (by increasing the rate of digestion of e.g. starch and protein or altering the solubility or tertiary structure of NSP) the microbiome will rapidly adapt to this new ecology and reorient itself accordingly. However, I find it a little difficult to accept that the major mechanism of a xylanase o ...
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Location:Orkney, Orkney, United Kingdom
Profile: Academic / scientific
Occupation: Research
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