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Participation in Forum on November 4, 2019
Lalit Belwal I totally agree with you. When it's a matter of maternal antibody our prime motive should be to negate these antibodies. But it should be in our mind that what we are going to negate can protect birds up to first fourteen days or not. If maternal antibodies can protect birds for at least fourteen days we should not negate. If maternal antibodies are not protective but at the same time ...
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Pranjal Pranbindu Kalita likes the comment:
Dr. Charles Ibe, Dear Dr. Ibe, I am in agreement with you. The purpose of 0-3 day ND vaccination (I/O;I/N) is not to induce antibody-mediated humoral immunity. Instead, this method invokes the phenomena of viral interference and interferon-mediated innate resistance, a well know fact with regards to all myxo- and paramyxoviruses. This imparts local immunity preventing entry of field virus via the ...
Pranjal Pranbindu Kalita likes the comment:
Good work. day old live vaccine can be a reason for the failure of vaccine as it is neutralized by mab. Many people are now a days attributing the failure to emergence of new strains of nd which may require revision in the thinking. n.d is known to be a single strain for a long time.
Pranjal Pranbindu Kalita likes the comment:
i think the brand of vaccine used in this trial also matters.
Pranjal Pranbindu Kalita likes the comment:
Dear In high epidemic area, such as the middle east -especially gulf region-, we should vaccinate at day old in spite of high maternal abs level in chicks due to vaccination at day old will provide local immunity which important for protection against Nd challenge and prevent filed strain to attach with receptors So you can review about using ND vector vaccine which did not interfere with maternal ...
Participation in Forum on October 21, 2019
Pieter Kuhne Challenge infection for determining maternal antibody interference is a moon-lander.... Challenge infection is done for vaccine trials for potency test..Hope this kind of high research happens in your lab but not in general.. regards
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Pranjal Pranbindu Kalita likes the comment:
Serological evaluation is a way of estimating the protection levels in the flock. This is the guideline to judge the effectiveness of vaccines practiced everywhere.Challenge is another tool. It requires a controlled facility to expose birds to live virus and count the mortality. Somebody with facility can take it up. it is a proven fact that birds with higher levels of antibodies live better when ...
Pranjal Pranbindu Kalita likes this technical article:
Introduction Maternal immunity for Newcastle Disease (ND) can be quantified with Haemagglutination Inhibition(HI) test. Titres are expressed as log 2 values. Titres in a group are analysed statistically and mean titre in a group depicts status of flock immunity. Quantification of HI titre at day old age and subsequent quantification at weekly interval can determine the maternal antibody interfere ...
Participation in Forum on September 26, 2019
In my opinion robenidine is the safest option in layer for prevention.. However once the disease is evident amprolium is the therapeutic option..
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Pranjal Pranbindu Kalita likes the comment:
From our experience, You don't need to play too much with feed because the most known broiler breeds have nutrition Guieds for better results, so I prefere to concentrate on ventilation and house tempretures, if you can keep them near the optimum case you'll properly reduce the Ascites problem. this will increase your cost in winter but at the same time will save your birds.
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Location:New Delhi, Delhi, India
Profile: Academic / scientific
Professional Title: MVSc