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Additional Methionine for the Transition Phase

Published on: 04/06/2020
Author/s : Dr. Claudia Parys

Methionine is a nutritional and functional essential amino acid. Supplementation during the transition phase and at the beginning of lactation improves the health status and performance of high-producing dairy cows. The transition phase is the most critical period in the production cycle of dairy cows and is characterized by a challenged immune system. Factors which have an influence on this are ...

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Joe Magadi Joe Magadi
Manager
April 6, 2020
Thank you Claudia. Very interesting observations. In our organisation we have developed a product that combines rumen inert methionine, choline, glycerine, C18:1 and glycerine together with vitamin E and organic selenium and the results are equally exciting.

Have you considered combining methionine with histidine?
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Claudia Parys Claudia Parys
Ruminant Nutritionist - Global Technical Support
Evonik Animal Nutrition Evonik Animal Nutrition
Hessen, Germany
April 9, 2020
Joe Magadi
The combination with histidine would make it less economically efficient. The high load of the first limiting amino acid methionine (85%) together with its unique coating makes Mepron the most efficient methionine source for ruminants. Histidine is pretty expensive even in a unprotected form.
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Joe Magadi Joe Magadi
Manager
April 9, 2020
Claudia Parys

Thanks for your response. It makes sense.
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Rudra Desai Rudra Desai
Ph. D. fine chemicals and pharmaceuticals
April 11, 2020
This amino acid didn't require atall
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Syeedmojtaba Syeedmojtaba
Animal Nutritionist
April 28, 2020
It is a very important and interesting discussion about dairy cows. We are pleased with you.
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Hazem Hassanien Hazem Hassanien
Ruminants Nutrition Specialist
May 16, 2020

Claudia Parys

No one can deny that the vital role of rumen protected methionine, but the main challenge of using protected amino acids are very costly. I think that if the ration are balanced for amino acids and covered for limited amino acids, it will be decreased the feed costs.

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Claudia Parys Claudia Parys
Ruminant Nutritionist - Global Technical Support
Evonik Animal Nutrition Evonik Animal Nutrition
Hessen, Germany
May 19, 2020
Hazem Hassanien
The pure product is costly per kg. As Mepron supplies methionine in a highly concentrated form (85% DL-methionine), it helps covering the first limiting amino acid without using high amounts of protein feeds that are more expensive per unit of methionine. In addition, it helps to reduce the nitrogen load and to improve the nitrogen efficiency. As total feed costs are reduced with less CP and better amino acid balancing, Mepron helps to increase the overall profitability.
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Hazem Hassanien Hazem Hassanien
Ruminants Nutrition Specialist
May 19, 2020
Claudia Parys
Mepron is considered as NPN and produced normally by rumen microbes. It could be dispense with it in the dairy ration. On the other hand it doesn't consider as a true protein.





Regards
H
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Majid Farrokhi Majid Farrokhi
Sales Manager at Evonik
Evonik Animal Nutrition Evonik Animal Nutrition
Hessen, Germany
June 1, 2020
Hazem Hassanien
Capacity of Microbial protein ( Methionine ) is not sufficient for high yield milk dairy cows and addition of Protected sources is needed in order to support the best performance of the cows.
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Joe Magadi Joe Magadi
Manager
May 17, 2020

Hazem,

You are right, protected amino acids are costly and there must be justifiable return on investment. I probably would not use it for cows yielding less than 8000lt. In any case, if you can determine the amount of yield of rumen microbial protein and compare that will milk output you tell whether or not the cow needs rumen protected amino acids. You also need to look at the whole diet and the RUP supply.

Reply
May 19, 2020

Hazem,

Cows do have a requirement for nitrogen in the rumen and for metabolizable amino acids in the intestine, the art of formulating a diet is precisely to cover these requirements in the most profitable possible way.

Mepron or any other protected amino acid is an amino acid, it is not a protein and it is not NPN, and it does not need to be, and it is intended to deliver its payload in the intestine, not to have an effect in the rumen (therefore, the word "protected").

A high producing cow rumen is just not capable of producing enough Methionine to cover its needs. Here it is the point where it comes RUP as Joe Magadi very rightly says, and the use of protected amino acids can be profitable at this stage.
Apart from the pure milk production (kgs, and fat and protein content) Methionine has other metabolic roles than can be very important in the transition stage.

Reply
Joe Magadi Joe Magadi
Manager
May 26, 2020
Hi Luis,

You are right, we now know methionine plays a role in hepatic lipid metabolism, and in reproduction by influencing the accumulation of fatty acids that supply energy and are essential to fertility in the endometrium. Reduction of methionine is also established as a novel cellular mechanism for regulating oxidation which is important under conditions of oxidative stress in transition cows.
Reply
May 27, 2020
Hi Joe,

Yes, every time more metabolic roles for methionine are discovered. Considering methionine just as a tool to improve milk protein yield is quite outdated...
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June 5, 2020
Sir, I do enjoy every bit of you discussion but I am a novist on level. However its highly interesting as it keeps me busy brain stormy. Thanks
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