Good attempt for providing latest information on DNA vaccines by Dr. Anas Kannnnn
I really appreciate the effort of Dr.Anas for providing us initial development on DNA Vaccines production for livestocks & poultry.
Dear Dr. Anas,
Thanks for providing the Info on DNA vaccines & its feasibility.
I wish to know more about its "Cons" too. If you have a maximum comparative data on DNV Vaccines Vs. Killed Vaccines Vs. Live Attenuated Vaccines with their Pros & Cons then please be update us.
Regards,
Dr. Jaydip
thanks for providing such a wonderfull information. hope this DNA vaccines will not have adverse effect on the birds and human being thant consumes the birds meat and egg
Good review Dr.Khan.It is a commendable job.
The problem with non-conventional vaccines like plasmid DNA vaccines, synthetic peptide, VLP (virus like particles ) , viral vector vaccines and others of the same genre is that they address only the surface antigens and produce antibodies against a limited antigenic spectrum of the infectious agent.
On the other hand the conventional vaccines, mainly the attenuated live vaccines simulate the infectious process, albeit a low grade non-symptomatic infection, and invoke antibodies to the entire three dimensional conformational protein structure of the surface antigens but also against the various intermediates and precursor proteins for the establishment of IMMUNITY ( not only antibodies ) and prevent the infection from virulent agent.
However continued research on nouveau concepts and adjuvants shall definitely lead to a more robust immunization regime in the future.
Thank you once again for bringing up the issue.
Dear Sir (Dr. Belwal),
Thanks for updating us on the comparative points between DNA vaccines & present conventional vaccines.
Regards,
Dr Jaydip