Karel Schat (Cornell University) discussed diagnosis, method of vaccination and other recommendations regarding this disease, during IPPE 2020 in Atlanta, USA.
Thanks you for revision and update on such a sturdy/hardy virus. Up to what extent is it true that the CIAV will not be vertically transmitted to the off-springs if their parents contain optimum level of antibodies against the same virus?
DR.R.N.Sreenivas Gowda Hello Dr. Srinivas, If CAV antibody found in parent and is mixed with vaccine virus and field virus, can these antibody protect its progeny?
Regarding recombinant vector CIAV vaccine construction rHVT to be used as a hatchery vaccination , no success yet, inserts expression cassettes VPs , no in vivo expression.Investigation using the CRISPR/Cas9 tool may be a possible solution to generate in the future rHVT/CIAV.
I made a clinical diagnosis of CIAV January 2021-for first time in Kenya. Awaiting for laboratory confirmation. Major hatcheries vaccinate ,and the combination with CIAV+ rHVT would be a good achievement in disease prevention.
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