Molecular mechanisms and new strategies to fight stresses in egg-producing birds

It is a wonderful article and opens up new aspect of handling oxidative stress in poultry. The authors mentioned that during stress, the feed intakes of birds dropped and that's why antistress mix supplied in water becomes more helpful in combating the stress. My point is, why not we include some organic mineral which are part of antioxidant defense mechanism of the bird body and lets not develop stress to a level where feed intake is dropped. I personally believe, providing some organic minerals/vitamins especially Selenium in feed could be more effective than water soluble supplements.

It is a wonderful article and opens up new aspect of using anti stress factors in laying stocks

It is a very interesting research work which has a great importance in the field. How many farms are implementing the recommendations of the project and what are their results?

Thank you for comments, I would like to stress the following: 1. Organic minerals will not solve the problem of the stress, their supplementation is effective only in the case of dietary mineral (Zn, Mn, Cu, Se) deficiency. If the diet is adequate in these minerals, there would not be much response in terms of antioxidant enzyme synthesis. The technology of supplying special vitagene-regulating mixture is dealing with improvement of adaptive ability of animals in stress conditions. This technology is considered to be " a fast-reacting tool" in the hand of nutritionist/technologists to deal with stressful situations in commercial poultry/animal production. Indeed, such situations are very often unpredictable and the usage of feed supplements in such situations has a low flexibility (one have to finish the feed in the feed bin, before anything can be added via feed). In contrast to this, usage the supplement with water gives an opportunity of fast reacting. 2. As for usage of such technology in industry, it is widely used worldwide, including Russia, Ukraine, Kazakhstan, Moldova, Egypt, Turkey, Thailand, Taiwan, etc. Such a tool helps in various stressful situations, from heat stress to mycotoxicosis, from immunosuppression to post-vaccinal stress, etc.

Dr Peter, excellent insightful story about the favorable action of possible nutritional agents to mitigate the negative effects of heat stress on monogastric performance. Taking advantage of the knowledge of the research team involved in the work, I would like to ask a question. Specifically in birds exposed to high temperatures, it would also not be important to evaluate the expression of mitochondrial uncoupling protein (UCP), whose activity decreases, and corticosterone hormone, which increases, precisely due to its recognized actions in the production of free radicals.

Its very interesting topic will help in layer farmer for keeping their farm healthy in critical situation and to produce better quality of eggs.

Water supplements are more effective than in feed supplies due to many well known factors affecting feed intake praticulary during heat stress. The response to organic ligands depends on mineral status of the feeds as said.