Antibiotic Resistance in APEC- Dr. Badrul Hassan

Thanks Dear,
It seems to be complex situation. I need answer to some questions.
1:- Did you confirm IB through PCR or in later stage (14 days after disease) through serology? It may be H9, ND or any other. Now for ND test of differentiation for vaccine & field strain is available in Pakistan.
2:- is your water free of E. Coli? E. Coli can be controlled through water sanitiser like chlorination, organic acids effective combination but take care while giving live vaccines, Best management practices & ventilation management.
Even for E. Coli some economical antibiotic can be used for recommended duration.
3:- Main issue seems to be in poor disinfection after flock sale/ before placement of new chicks.

Regards,
Jaffery

I do agree with the comments of Dr Jaffery. As your birds suffered a lot because of E. Coli, So, take hygienic/biosecurity measures to prevent E. Coli infection. Treatment is not the permanent solution. For the time being, you can choose an antibiotic after sensitivity test. Then apply.

But, after harvesting, biosecurity- proper cleaning. disinfection and house rest are very essential.

Bleaching powder is the best and cheapest source of chlorination. Chlorine content in drinking water in closed System(Nipple) should be 1.5 ppm and for open drinking 3 ppm. I am sure if followed, you would get rid of it.

Dear Aftab Anwar
Thanks for sharing - I hope you will endure!
In our work with poultry in Denmark and Russia, we have found that problems relating to the respiratory system are best regarded as secondary infections. We have found that when we reduce the ammonia level in the air, whereby we reduce the chemical inflammation of the mucosa in the respiratory system, many sicknesses "disappear" from the herd.
So, we think your primary focus should be on the quality of the manure. If it is pretty dry you know that the chickens have an OK digestion. When its wet you know three things: their digestion is not OK, the bacteria will have a feast in the wet droppings, and in that process, they will release high levels of ammonia from degraded amino acids.
Therefore, your main focus should be on getting the digestion of the poultry right. There are basically three ways to achieve this, one is to reduce the protein level, the second way is to introduce feed which favour bifidobacteria (fiber and prebiotic feed) and the third way is to introduce a tannin-containing feed additive as these are good at controlling Clostridia and other amino acid degrading bacteria.
We use successfully an extract from Sweet Chestnut to control unwanted microbial amino acid degradation - either as a stand-alone or as a combined solution.
Best wishes, Klaus