Yes, I agree with the statement. It is already proven that mycotoxins such as aflatoxin, ochratoxin, etc., can interfere with vitamin D/calcium/phosphorus metabolism.
Yes, mycotoxins interfere with normal matabolism of Vitamin D. However, mycotoxins interaction with vitamin D is important. It is the level of mycotoxin in feed which is important that interacts with the vitamin D. What level of mycotoxin in feed disrupts the vitamin D metabolism, which has not been researched extensively so far. Therefore, the mycotoxin- vitamin D interaction is inconclusive.
Dr. Ram Singh Bibyan
Principal Scientist
CIRB, Hisar
This is very interesting. But , we understand and know that one important quality of mycotoxin binders is that they do not bind or hamper the availability of vitamins including vitamin D, otherwise, egg shell formation and skeletal formation would be impaired. In this situation, therefore, the nutritionist should watch the type of ingredients and the level of mycotoxin contamination in them, in order not to inform or warrant using higher levels of mycotoxin binders in the feed. This would not only reduce feed cost but enhance feed quality and efficiency.
Emmanuel Nwaotule Such "undesired adsorption" is something few people seem to think much about. And yet, it is why we do not use activated carbon, for example, which is great at adsorbing mycotoxins of all kinds but also binds nutrients of all kinds.
It is this selectivity that differentiates the different sources of bentonite around the world, with Ca-bentonites being more selective than Na-bentonites.
Interesting. Would anybody know what the maximum level of Aflatoxin should be (say roughly over a week) to avoid the interference? I would prefer to have data from experiments without binders.
Yes, mycotoxins hinder the mechanism of action of vit D regulation in the body including the absorption, of Ca from intestine, distribution of both bit D and Ca in the body including precipitation in the bone or immobilisation to the egg shell under the control of Calcitionin and parathyroid hormones. On autopsy of broiler chickens feed intoxicated, the long bones are fragile and green stick fractured.