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Choline in animal nutrition: Its role, sources and new approaches

Published on: 04/25/2021
Author/s : Carlos López, Export Area Manager at Liptosa

Although the first mentions to  “choline” date from XIX century  (In 1850, Theodore Gobley already described a substance “lecithin”, and then, in 1862, Adolph Strecker heated lecithin from bile, which generated a new nitrogenous chemical termed “choline”), choline’s role nutrition was not well known until 1930s. Since then, several researche...

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Dave Albin, Ph.D. Dave Albin, Ph.D.
VP, Nutrition & Extrusion Technologies
April 25, 2021
As mentioned here, the relative value of choline in mechanically-extracted oilseed meals should be determined. In particular, this is important when extrusion is used before pressing in order to more-fully liberate the lecithin (choline containing) from the seed.
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Ewa Sujka Ewa Sujka
Commercial Manager
LIPTOSA LIPTOSA
Madrid, Madrid, Spain
April 26, 2021

Dear Dave Albin, Ph.D.,
I would agree that the correct and detailed determination of nutrients value in our raw materials, for sure allows more precise formulations and better cost optimization.

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Dave Albin, Ph.D. Dave Albin, Ph.D.
VP, Nutrition & Extrusion Technologies
April 26, 2021
Ewa SujkaThank you very much. I would appreciate reprints or other information on this subject. In particular, the data in Table 1 and the data related to the histology are of interest.
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Ewa Sujka Ewa Sujka
Commercial Manager
LIPTOSA LIPTOSA
Madrid, Madrid, Spain
April 27, 2021
Dear Dave,
As mentioned in the article, both are our own studies carried out by Liptosa, one with collaboration of Complutense University of Madrid, and the table 1 is an analysis of several dose-reponse trials.
The use of vegetal coline has many advanatges for the animal and for the feed manufacturer, therefore I suppose for extrusion industry could be of much interest to evaluate this parameter.
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Siyanbola O.O Siyanbola O.O
April 30, 2021
Yes I am interested
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Ewa Sujka Ewa Sujka
Commercial Manager
LIPTOSA LIPTOSA
Madrid, Madrid, Spain
May 3, 2021
Dear Siyanbola O.O
We are glad to know about your interest, we will contact you soon.
Best regards
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Ram Singh Ram Singh
Ph.D. (Animal Nutrition)
May 3, 2021
With regard to choline in Animal Nutrition, I would like to state that choline is used to remove fat from the liver and protects the liver against those toxicants which result in fat accumulation in liver.
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Carlos López Tomé Carlos López Tomé
Veterinary Doctor
LIPTOSA LIPTOSA
Madrid, Madrid, Spain
May 4, 2021

Dear Ram Singh, you are right, Choline, among other functions, plays an essential role in the fat metabolism in the liver, preventing abnormal accumulation of fat within hepatocytes (fatty liver) by promoting its transport as lipoprotein and lecithin or by increasing the utilization of fatty acids in the liver.
NaturColin components provide also strong hepatoprotective functions, allowing CC replacement overcoming the technical disadvantages mentioned in the article.
Regards.

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Dave Albin, Ph.D. Dave Albin, Ph.D.
VP, Nutrition & Extrusion Technologies
May 4, 2021
Carlos López Tomé Along these lines, would this better utilization of fatty acids in the liver result in a meaningful increase in energy usage of dietary fats and oils? I also understand that the myriad biochemical reactions of the liver would likely proceed better without fatty liver.
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Carlos Martínez Amezcua Carlos Martínez Amezcua
May 23, 2021

I totally agree, each nutrient has several functions, that is why I do not like the concept of replacing some of them with others that could be related, or be converted, some times this conversion is not 100% efficient, specially under stress conditions, if under those stress conditions, one function is increased, the extra dosage of the replace nutrient Will not help at all, example, conditional essential nutrients as cysteine or selenium in glutation peroxidase activity, a deficiency of those nutrients can not be replaced by increasing betain or Vitamin E.

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Carlos Martínez Amezcua Carlos Martínez Amezcua
May 23, 2021

Carlos Martínez Amezcua, sorry for the mistakes, my Spanish translator betrayed me.

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Ewa Sujka Ewa Sujka
Commercial Manager
LIPTOSA LIPTOSA
Madrid, Madrid, Spain
May 24, 2021
Dear Carlos Martínez Amezcua,

I would like to add that in case of Naturcolin, we are talking about possibility of choice between synthetic source of choline: choline cloride and vegetal source of choline. We may find approach similarities with betaine: anhydrous or HCl, or methionine DL or MHA. All this options are suitable for animal nutrition, and proved to have good results.
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