Choline in animal nutrition: Its role, sources and new approaches
Published:March 3, 2021
Summary
Although the first mentions to “choline” date from XIX century (In 1850, Theodore Gobley already described a substance “lecithin”, and then, in 1862, Adolph Strecker heated lecithin from bile, which generated a new nitrogenous chemical termed “choline”), choline’s role nutrition was not well known until 1930s. Since then, several resear...
As mentioned here, the relative value of choline in mechanically-extracted oilseed meals should be determined. In particular, this is important when extrusion is used before pressing in order to more-fully liberate the lecithin (choline containing) from the seed.
Dear Dave Albin, Ph.D., I would agree that the correct and detailed determination of nutrients value in our raw materials, for sure allows more precise formulations and better cost optimization.
Ewa SujkaThank you very much. I would appreciate reprints or other information on this subject. In particular, the data in Table 1 and the data related to the histology are of interest.
Dear Dave,
As mentioned in the article, both are our own studies carried out by Liptosa, one with collaboration of Complutense University of Madrid, and the table 1 is an analysis of several dose-reponse trials.
The use of vegetal coline has many advanatges for the animal and for the feed manufacturer, therefore I suppose for extrusion industry could be of much interest to evaluate this parameter.
With regard to choline in Animal Nutrition, I would like to state that choline is used to remove fat from the liver and protects the liver against those toxicants which result in fat accumulation in liver.
Dear Ram Singh, you are right, Choline, among other functions, plays an essential role in the fat metabolism in the liver, preventing abnormal accumulation of fat within hepatocytes (fatty liver) by promoting its transport as lipoprotein and lecithin or by increasing the utilization of fatty acids in the liver. NaturColin components provide also strong hepatoprotective functions, allowing CC replacement overcoming the technical disadvantages mentioned in the article. Regards.
Carlos López Tomé Along these lines, would this better utilization of fatty acids in the liver result in a meaningful increase in energy usage of dietary fats and oils? I also understand that the myriad biochemical reactions of the liver would likely proceed better without fatty liver.
I totally agree, each nutrient has several functions, that is why I do not like the concept of replacing some of them with others that could be related, or be converted, some times this conversion is not 100% efficient, specially under stress conditions, if under those stress conditions, one function is increased, the extra dosage of the replace nutrient Will not help at all, example, conditional essential nutrients as cysteine or selenium in glutation peroxidase activity, a deficiency of those nutrients can not be replaced by increasing betain or Vitamin E.
I would like to add that in case of Naturcolin, we are talking about possibility of choice between synthetic source of choline: choline cloride and vegetal source of choline. We may find approach similarities with betaine: anhydrous or HCl, or methionine DL or MHA. All these options are suitable for animal nutrition, and proved to have good results.
Good day,
It is quite intresting to note that the use of Natural choline source has been reviewed and shown to improve zootechnical animal performance and overcome the technical disdavantages associated with the practical use of Chemical Choline source (CC) in feed manufacture.
The following questions would then arise:
1. Would there be enough sustainable production capacity of the Natural source to support potential requirement. ?
2. To what extent has this technolgy been adopted in other regions and how are results ?
Dear William Ndindana As you say, the use of Natur Colin allows to overcome the technical disadvantages of synthetic choline sources. In relation to your questions, there should be no issues about production capacity. Note also that Natur Colin is already available in several markets across EU, Asia, Africa and America, with very possitive feedback in all of them, demonstrating its effectiveness regardless market conditions (diets, environment...)
I think this statement is incorrect.
How about the production of acetylcholine by neurons as a neurotransmitter?
Also how about the synthesis of phospholipids by not only the liver but also extrahepatic tissues in cell signaling and metabolism?
Please see “Principles of Animal Nutrition” by Guoyao Wu, CRC Press, 2018.
I have been using Cholin extensively in dairy formulation and nutraceutical products for cows in transition . I am interested knowing details of your product Natural cholin. Could you please share technical sheet. Thanks
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