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(Arabic) Natural alternatives with quick results: Liptocol for control of Escherichia coli & Coccilip for control of coccidia

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Ahmed Adel Ahmed Adel
Veterinary Doctor
April 2, 2018

Would you please give more data about the product?

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April 3, 2018
Ahmed Adel

- Coccilip: combination of acid oils as oil of oregano, plant extracts and medium chain fatty acids

- Liptocol: based on medium chain faty acids, glycerides of MCFA, botanicals and essential oils
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Atef Abou Zead Atef Abou Zead
professor of viral poultry diseases
April 2, 2018
The composition
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April 3, 2018
Atef Abou Zead

- Coccilip: combination of acid oils as oil of oregano, plant extracts and medium chain fatty acids

- Liptocol: based on medium chain faty acids, glycerides of MCFA, botanicals and essential oils
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PHILIP QUINN PHILIP QUINN
Research and Development Director
May 8, 2019
Simo Ibn Majdoub

which plant extracts, which botanicals and whicj essential oils????????
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Atef Abou Zead Atef Abou Zead
professor of viral poultry diseases
April 2, 2018

What are the oils found in Coccilip product for the control of coccidiosis?

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April 3, 2018
Atef Abou Zead Basically oil of oregano
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Atef Abou Zead Atef Abou Zead
professor of viral poultry diseases
April 4, 2018
Mechanism of action of essential oils and MCFA for controlling of coccidia
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April 5, 2018
Atef Abou Zead
Essential oils target different stages of the life cycle of Eimeria species, f.e carvacrol destroys spozoites. Phenols alter the cell membrane, increasing its permeability, generating a water imbalance and therefore cell death, due to this mechanism of action NO bacterial resistance to the activity of phenols does occur.
The main mechanisms of MCFA are the destabilization of the membrane by its incorporation in the bacterial cell wall, In addition to the direct lithic effects of MCFA, the activation of coccidial autolytic enzymes could also play an important role in the activity against pathogens . MCFA dissociate into protons and anions inside coccidia, lowering the pH. As a result enzymes are inactivated, which leads to the death of coccidia.
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Robert Gauthier Robert Gauthier
Doctor of Veterinary Medicine
April 12, 2018

Simo Ibn Majdoub Please do not create confusion, bacteria and protozoa do not respond the same way to EOs. At what dose do coccidia respond to EOs? Usually, the necessary inclusion rate is beyond the workable level in the feeds. At least it is the case with the antibacterial effect of EOs. Always ask for "in vivo" well-conducted trials.

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April 12, 2018
Robert Gauthier In my comment, quoted above, I talked about Coccilip, this product is used to help in the control of coccidiosis, it is not used in the feed but in the drinking water at 700 ml / 1000 L meanwhile Liptocol is another different product that helps in control of colibacilosis, it is used in drinking water also.
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April 13, 2018

Dear Dr Robert Gauthier,

The exact mode of action of EO on bacteria and protozoa remains unknown. It is a complex process, and is under investigation by various research centres all over the world.
What concerns the effect of EO on coccidia, we may talk about direct and indirect activity. It is proven that EO act over coccidian oocysts damaging or deforming its wall what leads to the leakage of oocyst content and its death.
An indirect activity of EO is provided by compounds that help the host to improve the general gut health, modulate the immunological response and in case of some EO prevent of pathogen adhesion to the intestine epithelium.
Another point that should be taken into consideration while working with EO, is the presence of synergies between different compounds, what allows you to provide formulas with a doses workable from technical and economical point of view.

Fell free to contact LIPTOSA team so we may provide you further information about this issue.

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Koot van der Walt Koot van der Walt
Marketing Director
April 12, 2018
Would aniseed oil be one of the essential oils?
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David Pickard David Pickard
Consultant
April 12, 2018
Don't forget that for use in the EU coccidiostatic/coccidiocidal additives require a zootechnical feed additive authorisation (whatever the active substance) and similar registration requirements may apply in other countries (in some cases such products would be considered veterinary medicines)
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April 16, 2018
Dear David, Dear All.

It is correct that In the EU any feed additive (not only with anti-coccidian properties) requires authorisation. In most of the cases, the additive is a single substance, for example Origanum vulgare extract. However, when you combine different feed additives and all of them had been previously authorised, there is no need to authorise this blend once again. The combination of feed additives and/or raw materials is considered premixture or complementary feed.

In case you precise any detailed information about our product, its classification under the scope of EU legislation frame work, do not hesitate to contact LIPTOSA team.
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July 20, 2018
Dear Dr Simo
are there any comparative study? , we want to try them in Tunisia .
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