Explore

Communities in English

Advertise on Engormix

Effect of copper nanoparticles administered in ovo on the activity of proliferating cells and on the resistance of femoral bones in broiler chickens

Published: June 1, 2023
By: Natalia Mroczek-Sosnowska 1, Monika Lukasiewicz 2, Dobrochna Adamek 1, Maciej Kamaszewski 1, Jan Niemiec 2, Agnieszka Wnuk-Gnich 2, Abdullah Scott 3, André Chwalibog 3,4 & Ewa Sawosz 4.
Summary

Author details:

1 Department of Ichthyobiology, Fisheries and Aquaculture Biotechnology, Faculty of Animal Science, Warsaw University of Life Sciences, Warsaw, Poland; 2 Department of Poultry Breeding, Faculty of Animal Science, Warsaw University of Life Sciences, Warsaw, Poland; 3 Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark; 4 Department of Animal Nutrition and Biotechnology, Faculty of Animal Science, Warsaw University of Life Sciences, Warsaw, Poland.


Abstract

The objective of this study was to evaluate bone resistance after in ovo administration of copper nanoparticles (NanoCu) and to determine the number of cells positive for proliferating cell nuclear antigen (PCNA) in the femoral bones of broiler chickens (n = 12 per group). The study demonstrated that femoral bones from the NanoCu group were characterised by a higher weight and volume and by significantly greater resistance to fractures compared to the Control group. NanoCu promoted the proliferation of PCNA-positive cells in the long bones of chickens. A significantly higher number of PCNA-positive cells in the bones of birds in the NanoCu group compared with the Control group (137 and 122, respectively) indicate a stimulatory effect during embryogenesis. Considering the improvement in bone resistance to fractures and the effect of NanoCu on the number of PCNA-positive cells in femoral bones, NanoCu may be an alternative agent to minimise the ever-present problem of weak bones in broiler chickens.

    

Keywords: Bone density, bone formation, chickens, copper, in ovo administration, nanoparticles.

   

Abstract published in Archives of Animal Nutrition, 71:4, 327-332, DOI: 10.1080/1745039X.2017.1331619.

Related topics:
Authors:
Monika Łukasiewicz
University of Warsaw, Poland
University of Warsaw, Poland
Abdullah Scott
Recommend
Comment
Share
Profile picture
Would you like to discuss another topic? Create a new post to engage with experts in the community.
Featured users in Poultry Industry
Manuel Da Costa
Manuel Da Costa
Cargill
United States
Shivaram Rao
Shivaram Rao
Pilgrim´s
PhD Director Principal de Nutrición y Servicios Técnicos de Pilgrim’s Pride Corporation
United States
Karen Christensen
Karen Christensen
Tyson
Tyson
PhD, senior director of animal welfare at Tyson Foods
United States
Join Engormix and be part of the largest agribusiness social network in the world.