Vaccine protection of chickens against antigenically diverse H5 highly pathogenic avian influenza isolates with a live HVT vector vaccine expressing the influenza hemagglutinin gene derived from a clade 2.2 avian influenza virus
Published on: 02/20/2017
Author/s : Darrell R. Kapczynski 1; Motoyuki Esaki 2; Kristi M. Dorsey 2; Haijun Jiang 1; Mark Jackwood 3; Mauro Moraes 2; Yannick Gardin 4.
/ 1 Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, Athens, GA, USA; 2 Ceva Animal Health, Lenexa, KS, USA; 3 Department of Population Health, College of Veterinary Medicine, The University of Georgia, Athens, GA, USA; 4 Ceva Animal Health, Libourne, France.
Since 1990's, there has been a significant increase in the number of highly pathogenic (HP) avian influenza (AI) outbreaks and also in the number of birds involved in those outbreaks [1,2]. The most notable of these recent HPAI outbreaks is a series of H5N1 outbreaks started in China and Hong Kong since 1996, which then spread to other parts of the world including South-East Asia,...