Ensapuh Veterinary Services limited the vaccine is not used in broilers as
1) it is too expensive
2) the idea is that you vaccinate breeders and produce mycoplasma free broilers - horizontal transmission in broilers between flocks is not that important and most flocks will get through without needing treatment.
3) you should do MG and MS live vaccines
4) Maternal antibody is thought to have no effect in progeny in MG and MS epidemiology. - it has been suggested that maternal antibody may even increase efficiency of vertical transmission.
5) MG and MS free broilers at hatch will not need prophylactic antibiotics for "vaccine reaction" to newcastle vaccination.
Some of these vaccines are used in turkey broilers where the life span is longer as you would vaccinate at 3 weeks and expect protection to be starting at 6 weeks of age. Also this could be useful in long lived broilers (label rouge, yellow chicken, etc).
Hello Dr. Chris Morrow
I did the MG Ts11 vaccination at the Farm Broiler Breeder at 28 days of age.
Before vaccination, I gave prevention MG with Tylmicosin for 5 days.
The distance between treatment and MG Ts11 vaccination It was 5 days and 10 days.
The Amean description of ELISA MG titer, 6 weeks after vaccination is as follows:
A. Distance between administration of Tylmicosin and MG TS11 vaccine for 5 days.
Shed1, Amean 198, Cv% 205, Serum no: 18, Neg: 17, Post: 1,% Post: 6
Shed2, Amean 320, Cv% 98, serum no: 19, Neg: 16, Pos: 3,% Pos: 16
Shed3, Amean 33, Cv% 209, Serum no: 18, Neg: 18, Post: 0,% Post: -
shed4, Amean 82, Cv% 161, Serum no: 18, Neg: 18, Post: 0,% Post: -
shed5, Amean 40, Cv% 200, Serum no: 18, Neg: 18, Post: 0,% Post: -
shed6, Amean 70, Cv% 221, Serum no: 18, Neg: 18, Post: 0,% Post: -
B. The distance between Tylmicosin administration and MG TS11 Vaccination for 9-10 days.
shed7, Amean 691, Cv% 79, Serum no: 19, Neg: 10, Post: 9,% Pos: 47
shed8, Amean 942, Cv% 80, Serum no: 18, Neg: 7, Post: 11,% Pos: 61
shed9, Amean 790, Cv% 59, Serum no: 18, Neg: 10, Post: 8,% Pos : 44
shed10, Amean 767, Cv% 61, Serum no: 18, Neg: 8, Post: 10,% Pos: 44
shed12, Amean 943, Cv% 63, Serum no: 18, Neg: 6, Post: 12, % Pos: 67
there are several questions namely
1. Is the distance between the administration of Tylmicosin and the MG Ts11 vaccination for 5 days too close so that the % positive result is zero.
2. Is the withdrawal time of tylmicosin in the bloodstream for 5 days is not enough, thus killing the MG Ts11 vaccine.
3. Will it be at risk for MG field challenges because the MG TS11 titer is very low
4. Is it necessary to repeat vaccination in cages 1-6 for MG Ts11 or just take serum for the second ELISA test to know development Titer .
Ask for advice and opinions from all experts and experienced for these problems.
Thank you very much.
Strict biosecurity and all-in-all- out is best for Mycoplasma prevention. Antibiotic such as erythromycin, tiamulin. tetracyclines are used to alleviate clinical signs and reduce production losses. Mycoplasma gallisepticum may develop resistance against used antibiotics. Killed vaccines are used to breeder farms against Mycoplasma.