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Simultaneous replacement of ZnO and antibiotics with a Natural NGP to prevent PWD and maintain performance in pigs in field conditions in Spain

Published: September 4, 2019
By: M. Sevastiyanova*, C. Gougoulias*, A. Khadem*, † * Innovad , BELGIUM † Laboratory of Animal Nutrition, Faculty of Veterinary Medicine, Ghent University
Simultaneous replacement of ZnO and antibiotics with a Natural NGP to prevent PWD and maintain performance in pigs in field conditions in Spain - Image 1
Introduction
Antibiotics and pharmacological levels of ZnO are common recommendations for prevention of PWD and improvement of growth performance in farms (1). The EC has scheduled a ban on ZnO as of 2022 and increasing incidence of AMR requires restrictive and prudent use (2).
This study investigated the effectiveness of an in-feed complex alternative formula of esterified butyrins, medium chain fatty acids, plant extracts and essential oils (Lumance®, Innovad®, Belgium) on PWD incidence, ADWG and FCR in growing pigs, weaned without ZnO and antibiotics on real farm conditions in Spain. 
Materials and Methods
Set-up: on-farm swine integrator in Lleida, Spain. Eighty (80) pigs (40 males/40 females), weaned at D21 allocated in two groups on a random principal.
Control group: regular pre-starter and starter feed supplemented with ZnO (D21-D42: 2500 ppm and from D43 until the end of the growing period: 1500 ppm) and neomycin (D21 - D 42: 150 ppm) whereas, the trial groupreceived no ZnO and neomycin and was supplemented with 4 kg/T Lumance®.
The average BW of the pigs at weaning was 5.836 kg and 5.897 kg for the control and trial groups, respectively. The trial period was from D21 until transfer to the fattening stage.
Parameters followed:growth performance, ADWG, incidence of diarrhea cases, mortality, feed consumption, FCR and economic evaluation.
  • All animals suffered from diarrhoea were treated with injectable enrofloxacin and responded to the treatment with the exception of one animal from the control group that died at D23
  • The increase of cost at 0.403 € / animal in the Lumance® (4 kg/T) group was completely offset by the improvement in the overall performance parameters
  • Since this trial, Lumance® has been implemented as the regular program to completely replace ZnO and Neomycin for the whole production of pigs in this and other integrators, totalling ~10 million pigs in Spain (supplemented at a lower dose 3 kg/T)
 
Simultaneous replacement of ZnO and antibiotics with a Natural NGP to prevent PWD and maintain performance in pigs in field conditions in Spain - Image 2

Conclusions and Discussion 
  • Lumance® has proven until now in real large-scale farming conditions in Spain
  • A highly effective program
  • For simultaneous replacement of both ZnO and Neomycin (used traditionally to prevent post-weaning diarrhoea)
  • Whilst improving the performance parameters of the treated animals
IntroductionAntibiotics and pharmacological levels of ZnO are common recommendations for prevention of PWD and improvement of growth performancein farms (1). The EC has scheduled a ban on ZnO as of 2022 and increasingincidence of AMR requires restrictive and prudent use (2).This study investigated the effectiveness of an in-feed complex alternativeformula of esterified butyrins, medium chain fatty acids, plant extracts andessential oils (Lumance®, Innovad®, Belgium) on PWD incidence, ADWGand FCR in growing pigs, weaned without ZnO and antibiotics on real farmconditions in Spain. 

(1) Gesellschaft für Ernährungsphysiologie der Haustiere. Ausschuss für Bedarfsnormen. 2006. Energie- und Nährstoffbedarf landwirtschaftlicher Nutztiere, vol 4. Empfehlungen zur Energieund Nährstoffversorgung der Schweine, 10th ed. DLG-Verlag, Frankfurt am Main, Germany.

(2) Vahjen et al, High dietary zinc supplementation increases the occurrence of tetracycline and sulfonamide resistance genes in the intestine of weaned pigs. Gut Pat

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Authors:
Dr. Alireza Khadem
Innovad
Dr. Milena Sevastiyanova
Innovad
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Steffen Hansen
PIG.dk
2 de octubre de 2019
How many replicates were there per treatment group? The body weight at the trial end is mentioned, however, you do not mention trial duration in days? I do not understand the inclusion rate of ZnO in the control group as you continue with 1500 ppm even after a three week period with 2500 ppm? If you continue to supplement pharmacological levels of ZnO beyond 2-3 weeks it can reduce animal performance. When you mention that your client supplement only 3kg/t instead of 4kg/t shown in the trial it must be justified in some way - could you elaborate on that?
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