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Protecting animals from ingested mycotoxins

Published: October 26, 2020
What should we do if we have implemented all 3 of the 4 steps of the Mycotoxin Management Program – Forecast Crop Contamination, Secure Storage and Screen finished feed – and still find a multiple mycotoxin contamination in the feed? What if we do not have any choice in the matter, as animals need to be fed?  We can try to avoid feeding such a feed to more sensitive species and a...
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 Julia dvorska
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Joe Magadi
8 de diciembre de 2020
Would combining a mycotoxin binder with selenium and vit E help with the oxidative stress?
 Julia dvorska
15 de diciembre de 2020
Joe Magadi thank you for your comment! Indeed, additional antioxidants as Se and vit E would definitely help to combat oxidative stress caused by mycotoxins since one of the mechanism of their actions considered to be prooxidant effect.
Akos Mesterhazy
Cereal Research Non-Profit Ltd.,Hungary
5 de enero de 2021

I think that the best way is the prevention of the preharvest contamination. When you see the latest (4th) edition of Compendium of corn diseases, Aspergillus flavus was reclassified as mainly of field origin. From the Fusarium spp. this is not new. Most of the wheat and maize genotypes produce toxin contamination proportional with the visual severity, but a changing rate 10-20 % show overproduction or lower toxin rate, governed possibly by other mechanisms. As there are 10-fold or larger differences between genotypes, this can be used for restriction of the susceptible genotypes. This can significantly decrease the toxin pressure. A smaller toxin concentration can be neutralized with a much higher efficacy with a reducing method. When a consequent breeding program is made, you might have a very significant progress at low additional costs.
Greetings, and I wish you a successful application.
A. Mesterhazy

 Julia dvorska
12 de enero de 2021
Akos Mesterhazy you are absolutely right - to use resistant to fungal growth genotypes of maize and wheat would be the first and important step in prevention of preharvest contamination!
dr murad ali
12 de enero de 2021

We would have to prevent our animal from fungus growth feed. It cause huge problem to milking animal .toxicity having harm effect on animal. We must use toxin binder on daily basis to prevent Rumen and intestinal toxicity

 Julia dvorska
2 de febrero de 2021
dr murad ali indeed mycotoxins influence rumen fermentation and microflora causing different negative effect including decreased milk yield and milk fat
Peetambar Dahal
UC Davis - University of California
1 de febrero de 2021

Agreed with Akos above.
After proposing preharvest interventions (https://doi: 10.3389/fmicb.2019.02528), the authors have taken the approach to improve feed quality (https://doi.org/10.3390/toxins11100565). Both of these approaches were published in this forum. Regarding field fungus like Fusarium, similar preventive approaches need to be pursued. Downstream maintenance of value chain would further require maintenance of moisture to avoid insect infestation and nutrient losses. Even fortified foods/feeds lose nutrients at high moisture content. Until above approaches are used, mycotoxin absorbents should be continued.

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