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Introduction. Organic selenium (OSe) has an advantage in reducing oxidative stress in comparison to inorganic forms and incorporates into skeletal muscles, kidney, liver, and gastrointestinal mucosa proteins as selenomethionine and selenocysteine. It is an essential micronutrient for fish (Martinez-Alvarez et al., 2005). Yeast cell wall has been proven as an immunostimulant and health improver for fish and other animals (Selim & Reda, 2015). Materials...