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Comparison of DL-selenomethionine with other sources of selenium on performance, glutathione peroxidase activity and tissue selenium concentration in young broilers

Published: July 29, 2013
By: F. Yan, B. Wuelling, and M. Vazquez-Anon Novus International Inc. St. Charles, MO
A battery study was conducted to evaluate effect of different sources of selenium (Se) on growth performance, glutathione peroxidase (GPx) activity and tissue Se deposition of young broilers. A semi-purified diet containing corn starch, dextrose, and torula yeast was formulated to meet requirement of broilers for all nutrients except Se. The Se level was formulated to be 0.11 ppm but analyzed to be 0.23 ppm. The study consisted of 9 treatments - negative control with no added Se; 0.30 ppm added Se provided by sodium selenite (SS), DL-selenomethionine (DL-SeMet) (MINTREX® Se, Novus International, Inc.), two commercial selenized yeast products, methylselenocysteine (MeSeCys), or combination of SS and SeMet with each providing 0.15 ppm added Se; and 0.15 ppm added Se from SS or DL-SeMet. Each of the 9 test diets was fed to 8 replicate pens of 8 male broilers. Body weight, FCR, feed intake, and mortality were measured on d 6, 13, 20 and 27. Plasma and liver GPx activity was determined on d 7, 14, 21, and 28. Liver and breast Se concentration was analyzed on d 28. On d 35, breast muscle, liver, kidney, and skin/fat samples were taken for Se determination. Data were subject to one-way ANOVA with statements of significance based on P<0.05. Despite of semi-purified diet, birds from all treatments performed well with optimal growth rate and FCR. Growth performance and GPx activity were not significantly affected by dietary treatments throughout the trial. On d 28, DL-SeMet increased concentration of Se in both liver and breast whereas selenized yeast, MeSeCys, and SS significantly increased liver Se concentration only. On d 35, breast muscle, liver, kidney, and skin/fat Se concentration was increased significantly only by DL-SeMet. In summary, DL-SeMet was more available for deposition in liver, breast muscle, kidney, and skin/fat than selenized yeast, SS, or MeSeCys when added to provide 0.15 or 0.30 ppm Se in young broiler diets.

Key words: broiler, selenomethionine, selenized yeast, sodium selenite, methylselenocysteine
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