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High fidelity CRISPR/Cas9 increases precise monoallelic and biallelic editing events in primordial germ cells

Published: July 30, 2019
Summary
The chicken is a useful animal model for biological research and can be used to produce biopharmaceutical products that cannot be produced in mammalian bioreactor systems. Chicken meat and eggs derived from 70 billion chickens yearly are an important source of high quality protein, vitamins and minerals in the global economy. The ability to precisely edit the chicken genome to introduce or test g...
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Authors:
Helen Sang
Roslin Institute
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Michael McGrew
Roslin Institute
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