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Extrapolating data from in vitro to in vivo, and the transition of animal trial data to field observations

Published: September 15, 2022
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Authors:
Doug Korver
University of Alberta
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Danial Farhadi
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David Wicker Ph. D.
Fieldale Farms
20 de septiembre de 2022

The use of Challenge conditions and coccidiosis challenges in an experiment makes the interpretation of research as it applies to commercial conditions more difficult. I have found that reducing density and feeding a consistently good quality diet will enable a production manager to determine which products work in his operations and the products that give a positive return.

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Doug Korver
University of Alberta
20 de septiembre de 2022
David Wicker Ph. D. Those are very good points and highlight the difficulty of taking results obtained in small scale research (where we can expect a proportion of birds - i.e. the negative control - to show the ill effects of the challenge) and attempting to learn what works in the field (where the loss of productivity would be unacceptable).
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