Discussion created on 04/05/2020

Characteristic of AI-antibody titre in infected chickens

I would be grateful if somebody tell me the pattern of Ab- titre following AI infection in chickens 1-Does Ab-titre raise immediately after infection of chicken? 2-For how long does the raised titre persist and does it undergo regression to base line antibody titre before it escalate again?

Anonymous query
Saudi Arabia
Biologist
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April 6, 2020

LPAIV infection can be detected through AGID serological surveillance using egg yolk as early as 7 days post-inoculation, but use of HI or ELISA tests may delay detection by an additional 4 days [Mariana Sa´ e Silva & D.E. Swayne, 2012. Avian Diseases, Vol. 56, No. 3, 2012, Pages 601–604]

Furthermore, immunogenicity of serotypes varies. In H9N2 virus-infected chickens, the antibody response was severely suppressed - in contrast to the robust antibody response in chickens infected with H6N2 virus [Xing et.al., 2008. J Gen Virol 89(Pt 5):1288-1299].

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Anonymous query
Saudi Arabia
Biologist
April 7, 2020
Thank you so much for that valuable information
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April 7, 2020
How about in young chick? if we saw high HI titer of H9 in 10days broiler ( more than 4). where the antibody come from? the field infection or MDA.
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April 8, 2020
pham huu nhon Most likely maternal antibodies.
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Anonymous query
Saudi Arabia
Biologist
April 8, 2020

To what thing do we attribute the delay in detection of AI infection? Does that occur with ND and IB how many days needed for them to detect their infection?

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April 9, 2020
Salah Mohammed For immediate detection, PCR with clinical signs may be helpful. Seroconversion may take different time for different viral agents based on type of antigen, degree of challenge and duration of exposure.
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Zahed Abbasi Zahed Abbasi
VETRINARIAN
April 15, 2020
We are faced whit H9N2 in IRAN .all breeder flock will be vaccinated hence progeny have maternal antibody but in extreme condition like heat stress it doesn,t work also in complicated condition whit other agent like ND-IB-Mg....induces high mortality .one time vaccination in first week induces about LOG 5-6 after 3 weeks . it can be raised by second vaccination before lay
also in situation where there will be challenge whit field virus and anti body will be +8 LOG in HI
procedure and decreases like ND pattern .
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Anonymous query
Saudi Arabia
Biologist
April 17, 2020

What is the quantity of Elisa AI-antibody rises following infection of vaccinated chicken with AI vaccine?

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Fred Hoerr
Fred Hoerr
DVM, PhD, Diplomate ACVP, ACPV
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