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Swine gut health

Pigs are exposed to various challenges such as weaning, environmental stressors, unhealthy diet, diseases and infections during their lifetime which adversely affects the gut microbiome. The inability of the pig microbiome to return to the pre-challenge baseline may lead to dysbiosis resulting in the outbreak of diseases. Therefore, the maintenance of gut microbiome diversity, robustness and stability has been influential for optimum intestinal health after perturbations. Nowadays human and animal researches have focused on more holistic approaches to obtain a robust gut microbiota that provides protection against pathogens and improves the digestive physiology and the immune system. The swine gut microbiome is a complex and dynamic ecosystem harboring immensely diverse microbiota including bacteria, viruses, archaea, and fungi that ideally reside symbiotically in the gut of host animals. Among the microorganisms, the number of bacteria outnumbers other microorganisms. The microbiome robustness, the maintenance of diverse and functional microbiota in GIT is crucial for effective swine production. The microbiome robustness depends on the diversity of the microbiome, so it is not enough just to have the presence of a few different beneficial microbes. Accordingly, new strategies are required to manipulate the gut microbiome to prevent or revert unhealthy states caused by perturbations.
Vasileios Papatsiros
University of Thessaly
University of Thessaly
1. Introduction In recent decades, acidifiers have emerged as viable alternatives to antibiotics in swine diets, in order to stimulate optimal growth performance and prevent various enteric diseases. Antimicrobials have been used for more than 50 years to enhance growth performance and prevent various pig diseases (Gustafson & Bowen, 1997). There is growing public awareness of the relationship between the feed medication with antimicrobials as...
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Hans H. Stein
University of Illinois
University of Illinois
INTRODUCTION Producing pigs without using antibiotic growth promoters represents a challenge. Disease problems often are elevated and general performance is compromised on farms practicing non-medicated swine production. That is true in particular during the immediate post-weaning period whereas antibiotics can often be removed from diets fed to growing-finishing swine without introducing major disease problems (Wierup, 2001)....
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Alex Ramirez
University of Arizona
University of Arizona
ABSTRACT Enteric diseases are some of the most significant contributors to baby pig morbidity and mortality in the farrowing house. Piglet immunity must be maximized in order to provide them with the opportunity to thrive in the farrowing house. The production of consistent, high quality pigs is a goal all sow operations are working to achieve. By maximizing piglet immunity and using proper husbandry practices, scouring problems can be minimized....
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Dr. Andrew Van Kessel
University Saskatchewan
University Saskatchewan
It is now well recognized that the gastrointestinal tract of the pig is colonized by an abundant and taxonomically diverse microbial community. Because each of the species of organisms in the intestine possess a different "tool box" of metabolic capabilities, the relative proportion of different species of organisms changes in response to a variety of factors including age, diet composition, rearing environment and possibly genotype. Indeed, chemical composition...
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Probiotics, including live yeast and lactic acid bacteria cultures, have been reported to improve performance of weaned piglets. Milk replacer supplemented with Saccharomyces cerevisiae Sc 47 (Actisaf) and fed to weaned piglets showed improved postweaning growth and reduced number of enterotoxigenic E. coli (ETEC) in piglets after weaning, suggesting an immunomodulatory role of Sc 47. The objective of the present study was to evaluate the effect of Sc 47 dietary...
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Dr. Eric Cox
Ghent University
Ghent University
Escherichia coli (E. coli) are an important cause of disease in new-born and recently weaned piglets. In new-born piglets, severe watery diarrhoea can be caused by enterotoxigenic E. coli (ETEC) producing F4 (K88), F5 (K99), F41 and or F6 (P987) fimbriae. Colibacillosis in weaned piglets is the result of infection with F4+ or F18+ ETEC or F18+ verotoxigenic E. coli (VTEC). Besides fimbriae, ETEC produce thermolabile (LT), thermostable a (STa) and/or b (STb)...
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Elijah Kiarie
Poultry Health Research Network
Poultry Health Research Network
Introduction It is now accepted that weaning simultaneously subjects piglets to nutritional (e.g. loss of sow´s milk), psychological (e.g. mixing and moving) and environmental (e.g. change in ambient temperature) stressors and that these and other stressors contribute to growth depression typically observed immediately after weaning.  Reducing this post-weaning growth lag is critical as it not only affects...
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Salmonella control has a high priority in European pork production. It is a significant cause of human salmonellosis and causes major economic losses in the pork production chain, through reduced productivity, increased veterinary and hygiene control costs. Preventing the spread of salmonella to the consumer requires special control measures during slaughter and processing. The extra cost of these controls is increasingly being...
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Kenneth Mellits
University of Nottingham
University of Nottingham
Antibiotic Associated Diarrhoea (AAD) is diarrhoea caused by antibiotic (ATB) supplementation and usually occurring during or following ATB treatment. This phenomenon is highly spread in hospitals or health care houses where patients usually contract diarrhoea when receiving ATB treatment. The major identified bacteria causing AAD is Clostridium difficile . Many C.diff infections can be observed in UK hospitals causing up to death of some patients, mainly...
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Jeffery Escobar
Kemin Industries, Inc
INTRODUCTION Animals live surrounded by microorganisms (e.g., bacteria, viruses, parasites, etc.) and other antigens (e.g., allergens) that can activate the immune system, which is constantly challenged and must contend with subclinical infections on a daily basis. However, animals show clinical signs of disease quite infrequently because they are equipped with a highly-specialized immune system that affords protection against...
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Christian Lückstädt
ADDCON
Salmonella control has a high priority in European pork production. It is a significant cause of human Salmonellosis and causes major economic losses in the pork production chain, through reduced productivity, increased veterinary and hygiene control costs. Preventing the spread of salmonella to the consumer requires special control measures during slaughter and processing. The extra cost of these controls is increasingly being...
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FUELED BY THE INCREASED FOCUS ON THE PREVENTION OF ANIMAL DISEASES, THE BOOSTING OF THE IMMUNE SYSTEM VIA NUTRITION ALSO GAINS MORE ATTENTION. ANNELIES DIERICX AND JAN VANEYS EXPLAIN HOW A MIX OF COATED BUTYRIC ACID, BETA-GLUCANS, MOS AND A SELECTION OF BOTANICAL EXTRACTS CAN GIVE THE IMMUNE SYSTEM THE BOOST IT NEEDS.   ...
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Studies prove the effect of FORMI in piglets fed diets with different levels of protein As a consequence of todays common practice in pig breeding the gastro–intestinal system of piglets is not yet fully developed at the time of weaning. This may cause digestive problems and increase susceptibility to pathogenic bacteria such as E. coli and salmonellae. Formerly antibiotic growth promoters (AGP) were added to the feed in order to reduce the risk of infections and improve...
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Eurofeed Technologies s.r.l. has introduced two new non antibiotic growth promoters to the market called SUINACID and SHORTACID.They are a special blend of acidifiers and salts, studied to control some problem typical of the weaning phase but also in all swine life.In SUINACID composition there are 8 different kind of acids and salts, based on their different characteristics, they can act in different ways to control the most important and common weaning phase gut...
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Dr. Justin Tan Yu-Wen
Meriden Animal Health Limited
Piglet coccidiosis is caused by a protozoan parasite called Isospora suis. Although Eimeria debliecki has been known to cause clinical disease in piglets, it seems that the only important pathogenic species known to cause clinical disease in piglets is Isospora suis. This disease is very hard to eradicate and is commonly found on pig farms. ...
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Dr. Justin Tan Yu-Wen
Meriden Animal Health Limited
Porcine Intestinal Adenomatosus (PIA), or more commonly known as pig ileitis, comprises a disease complex with a group of conditions involving pathological changes in the small intestine associated with the intracellular bacterium Lawsonia intracellularis. The organism affects the mucosal epithelium of the small intestine, mostly the ileum and sometimes even the colon, causing hypertrophy with or without haemorrhage. The disease affects grower and finisher...
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Early postnatal morbidity and mortality are significant challenges to the swine industry. While piglets are exposed to many stressors soon after birth, gastrointestinal maladies are among the most severe. The neonatal intestine is instantly forced from being essentially inactive prior to birth to being the major "supply organ" responsible for providing nutrients to the piglet, which is born with very limited reserves. In addition to the required dramatic increase in function, the intestine...
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Diet can have a major influence on animal health. This impact can be beneficial or harmful if it leads to a proliferation of pathogenic bacteria. Dietary fibre (DF) is a component  of the diet that can have a major impact on gut health. DF is not readily digested by young pigs and forms the main substrate for bacterial fermentation in the intestinal tract. Various components in DF can either improve gut health or alternatively irritate the gut and cause diarrhea as a result. Thus, it is...
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NEXT Enhance® 150 is a standardised combination of thymol and cinnamaldehyde, an active ingredient of cinnamon extract. This combination acts to optimise gut flora equilibrium in the piglet and sow, leading to better feed efficiency and growth for the animal. Continuing to understand the mechanisms behind the consistent benefits in animal trials, Carotenoid Technologies SA (CaroTech®) has worked exclusively with the Zootechnical Department at the University of Ljubljana in Slovenia.,...
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Tobias Steiner
Agromed Austria GmbH
The diverse microbial flora of the gastro intestinal tract contributes to the nutrition, immunology, protection and therefore also health of the host animal. The vast limitations opposed to...
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