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Meta-analysis of individual and combined effects of mycotoxins on growing pigs

Published: June 13, 2018
Introduction Cereals are particularly susceptible to fungal contamination during both the pre- and postharvest stages. Many of these fungi are producers of mycotoxins, which are a chemically diverse group of secondary metabolites with a wide range of toxic effects (Bryden, 2012). The contamination of grain by mycotoxins represents a major concern worldwide in the pig production chain, since th...
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Ines Andretta
Universidad Federal Do Rio Grande do Sul UFRGS
Marcos Kipper Da Silva
Luciano Hauschild
UNESP - Universidad Estatal Paulista
Raquel Melchior
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Trevor Smith
Poultry Health Research Network
18 de junio de 2018

I think this is a very helpful contribution to our understanding of mycotoxicoses in pigs. Despite the limitations of this type of meta-analysis, it is very interesting to see the quantitative differences in feed intake and weight gain of pigs comparing individual and multiple co-contaminant challenges. This certainly helps us understand the increased severity of response when pigs are fed naturally-contaminated diets compared to the feeding of an equivalent amount of an individual mycotoxin. This also stresses the challenge in arriving at "safe" levels of feeding individual mycotoxins. Government regulatory guidelines should be changed to take this into account.

Néstor Serra
Adiveter SL.
20 de junio de 2018
Congratulations to the authors of the article. Regarding your comment, Mr. Trevor Smith, I totally agree with you: guidelines should take into account the multi-contamination. Another point is that government guidelines are based on performance but at lower levels we can already see negative effects on animal health.
Guilherme Bromfman
29 de junio de 2018
This is a great way to approach the problems with mycotoxins in swine. There is a clear disparity between levels used in scientific papers and levels commonly found in the field. This paper can help producers to make a more precise decision on managing the risk of mycotoxins. The combination of mycotoxins is a clear factor and it was greatly discussed in this paper. Well done to all the authors and looking forward to seeing further materials on this line.
Augusto Villarreal
INTA Argentina
29 de junio de 2018
This is an outstanding work...Congratulations to the team. This shows how important it is to conduct an analysis of the raw material before entering the farm.
Danko Vujošević
Patent Co.
28 de agosto de 2018
Its fantastic study indeed. Once again we have a clear sent massage across concerning utmost importance of synergistic effect of combined mycotoxins present in the feeds.
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